“nominally significant”

For daily gain, only the marker chr2_3566521_A_C was nominally significant (p-val = 0.025) (Additional file 7 ) but it did not reach significance after Bonferroni correction for multiple testing (p-val ≤ 0.05/36 = 0.0013).

The results of the SLDP genetic effect predictions were worse than what was expected with only one of six of the matching histone mark and cell types being nominally significant and none after false discovery rate (FDR) correction of 0.05 (Fig. 6a ).

Only variants with a nominally significant p -value were considered for phasing.

Results The allelic frequencies of the SNPs rs3211851, rs3173798, and rs3211908 showed nominally significant differences between the PDT responders and non-responders.

Finally, we required that either the mean squared effect size of the LoF burden tests or the duplications was nominally significant at the α = 0.05 level for each trait.

Accordingly, nominally significant associations, especially those based on small cell counts and wide confidence intervals, should be interpreted as preliminary reporting signals rather than definitive findings.

If several groups publish the same nominally significant association and these are combined, then the problem arises [ 11 ]. 5.2.

The correlation with age ( R = −0.1, p = 0.71, n = 16), waist circumference ( R = −0.05, p = 0.85, n = 16), height ( R = 0.63, p = 0.0092, n = 16) and weight ( R = 0.19, p = 0.47, n = 16) were statistically insignificant when multiple testing was considered, and again height is nominally significant.

Finally, the relatively wider confidence intervals in some sub-levels and nominally significant results suggest the possibility of chance findings.

In the RareIBD association analysis, two variants showed a nominally significant association with disease status: (i) variant p.N4041Y in the PKHD1L1 gene ( p nom = 0.0305); and (ii) variant p.R923Q in DCAF5 (family 0009, p nom = 0.0097).

Results A total of 408,343 CVs were analyzed; 13,017 were nominally significant ( p value for association test <0.05), and approximately 1% were located in genes.

Nominally significant p -values are shown in bold.

2 B), although multiple genes related to major histocompatibility complex (MHC) class II were nominally significant among this population (e.g., CIITA, CD74, HLA-DRA, HLA-DMA, HLA-DOA, HLA-DMB), suggesting pathways related to adaptive immune response may be downregulated.

10 , 11 A nominally significant SNP in AR has been identified in a British population, however this was only associated with early onset FPHL. 11 In addition to the AR locus, another locus which has been identified as strongly associated with MPHL is 20p11, first identified in a Suisse cohort and validated in British, Icelandic and Dutch populations. 12 A later study in a German cohort, with men exhibiting the Norwood‐Hamilton pattern of MPHL, corroborated these results. 9 Building on this were studies in a Chinese 13 and Korean 14 cohorts which also associated 20p11 locus with MPHL.

36 Significant associations between the CSMD1 gene and SCZ were observed in many reports, with nominally significant associations recorded for depression and bipolar disorder (BPD).

However, we found that sma-9(wk55) and unc-119(ed4) actually have a slightly smaller volume than wild-type during L1 arrest ( Figure 6 ), and these differences are nominally significant ( Table 3 ).

Genome-wide DNA methylation profiling identifies 2,143 significant DMRs Using bumphunter (cutoff = 0.15; 100 bootstraps), we identified 2,143 nominally significant DMRs in fibroblasts, comprising 1,314 (61.3%) hypermethylated and 829 (38.7%) hypomethylated regions.

Considering there were 136 MR estimates for region-level analyses and four MR estimates for global-level analyses, a Bonferroni-corrected value of p was set as 0.05/140 (3.57*10 −4 ), while a value of p less than 0.05 and greater than 3.57*10 −4 was considered nominally significant. 3.

Age at traumatization and sex With the exception of a few nominally significant findings in the CAPS sub-analyses, neither age at war nor sex were significantly correlated with the categorical PTSD or dimensional CAPS phenotype (Tables 2 , 3 ).

All P ‐values are nominal, with P < .05 considered nominally significant.

For instance, starting from RNA-seq data of whole blood samples from over 3000 individuals of different ages, a recent analysis found ANT1 to be upregulated with aging and nominally significant [ 173 ].

Owing to the exploratory nature and the number of subgroup analyses, results should be interpreted with caution, as nominally significant associations may arise by chance alone. 23 Analyses were done in SAS 9.2.

While the primary endpoint was not met, a supplementary analysis including all SBMs reported by primary and secondary caregivers demonstrated a nominally significant treatment effect of LIN 72 μg vs PBO for the SBM frequency rate.

Quality of reports provided by author-suggested and non-author-suggested reviewers There is nominally significant evidence that non-author-suggested reviewers obtained higher scores on Q6 (how well the reviewer substantiated their comments) and Q7 (comments on the author’s interpretation of results) in BMC Infectious Diseases (open peer review) than the scores obtained by reviewers in BMC Microbiology (single-blind peer review).

The black module exhibited only nominally significant evidence of association with monoamine levels.