Abstract

The survival probability without T1DM at study end was markedly lower in Black patients (73.95%) than in whites (85.93%), with a highly significant difference (log‐rank χ 2 = 40.099, p < 0.001).

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In patients with EoE, we observed a moderate inverse correlation between FLIP diameter and PEESS Child Dysphagia (r=‐0.34, p=0.015) and borderline significant weak‐moderate inverse trend between FLIP diameter and PEESS Parent Dysphagia (r=‐0.27, p=0.05).

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Sleep disturbance had a strong trend for increase from 23.1% to 34.7% to 42.5% (p=0.055).

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Patients with low BMD had lower mean weight Z scores (Mean ± SD of ‐1.08 ±1.61) compared to those with normal BMD (‐0.04 ± 1.02), with a trend toward significance (p=0.092).

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Children on blended diets showed a trend of weaning quicker (46.15 +/‐ 30.0) than children on formula (62.8 +/‐ 57.1; p=.122).

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In age‐adjusted logistic regression, a similar trend was noted, however did not reach statistical significance.

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Conclusions: There is an increasing trend in the use of GLP‐1 analogues among pediatric patients.

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While anxiety and depressive symptoms scores were not statistically significant, their confidence intervals reflect a possible trend that requires further exploration with larger and more diverse samples of children and young adults with IBD.

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While interventions targeting education and process standardization did not immediately improve BBPS scores, there has been a positive trend for the last 30 colonoscopies.

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While the primary endpoint was not met, a supplementary analysis including all SBMs reported by primary and secondary caregivers demonstrated a nominally significant treatment effect of LIN 72 μg vs PBO for the SBM frequency rate.

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