“nominally significant”

This included a nominally significant reduction in the necessity to start RRT [HR 0.45 (95% CI 0.21–0.97)].

78 genes within those CNVs were identified to show nominally significant association (48 genes), or a statistical trend in their association (30 genes) with the time animals spent on the open arms of the elevated plus-maze (EPM).

In the genetic variation score test, we tested whether allele-specific associations between ASD and autoimmune disorders can be found using nominally significant single-nucleotide polymorphisms.

In this case, we feel adjustment for multiple comparisons is not useful when presenting secondary outcomes or sensitivity analyses surrounding a single "main analysis." The secondary outcomes and sensitivity analyses are playing a supportive role to the main analysis, and generally provide the opportunity for greater caution in interpreting if the results are inconsistent between analyses, rather than an opportunity for declaring a result "significant" if any of the sensitivity analyses has a nominally significant p-value.

After residualizing the traits for age, sex and recruitment area a nominally significant couple association was also observed for cigarettes per day ( b = 0.10, (S.E. = 0.05)) (Supplementary Table 3 ) and the couple association for alcohol consumption became stronger ( b = 0.41, (S.E. = 0.02)).

Next, we assessed whether the nominally significant categories within each genomic region were statistically enriched.

However, according to the results from the IVW method, UTIs did not significantly increase the risk of any psychiatric disorders under the adjusted P-value threshold, although the effect of UTIs on MDD was nominally significant (OR = 1.06, 95% CI: 1.01–1.12, p = 1.91 × 10 −2 < 0.05).

Although these associations were nominally significant, they did not reach statistical significance after applying the Bonferroni multiple corrections, potentially due to the limited sample size.

Nominally significant associations are also not evenly distributed within functional classes of the immune system.

In addition, it is important to note that the difference observed between the placebo and solanezumab treatment groups for the ADCS-iADL might be viewed as being only nominally significant since it was not corrected for multiple comparisons.

Based on GLM the differentiation of the alleles across precipitation gradient (considering annual precipitation as a proxy) was nominally significant, but weak, for all three SNPs ( Figure 5 B, D, and F ).

The MAF of rs868005, rs13239907 and rs2856728 showed nominally significant differences between Type 2 PCV and control, but the MAF of only rs868005 remained significant after the Bonferroni correction was applied.

We ran the analyses together for all the AP and DE probesets with a total CFG score⩾4, then for those of them that showed stepwise change in the suicide completers validation cohort, then for those of them that were nominally significant, and finally for those of them that survived Bonferroni correction.

In contrast cg27411982 was still nominally significant even after the addition of 12 ASD-associated SNPs, four of which were independently associated and largely explained the association between the ASD PRS and DNA methylation (Additional file 1 : Figure S20; Additional file 2 : Table S10).

The traditional MR technique, inverse variance‐weighted (IVW) method, was employed to estimate effects, presented as beta (β) values with standard errors for continuous outcomes and odds ratios (OR) with 95% confidence intervals (CI) for binary outcomes; p values less than 0.05 were deemed nominally significant.

In contrast, nominally significant higher frequencies of WNH versus WH patients endorsed reasons driven by scientific discovery; “ To find new/better treatments for PD ” (87.5% vs 61.4%, respectively; p = 0.02), and “ To improve science and knowledge about PD ” (75% vs 46%, respectively; p = 0.01).

We observed three nominally significant differences in the frequency of three V-genes: TRAV23/DV6 , TRAV4 , and TRAV6 ( Figure 4A ).

Component correlations within age groups revealed a higher number of correlated and anticorrelated components in the young compared to the old group; 92 out of 378 edges showed significant correlations at the nominal level in the young group; for the old group, 64 out of 378 edges were found nominally significant.

In addition, a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g., miR-34, miR-4449, miR-146b-3p, and miR-23a-5p).

This study considered P -values less than 0.0004 (0.05/115, Bonferroni method) statistically significant, and meanwhile P < 0.05 was regarded as nominally significant 30 , 31 .

These genes, which were all at least nominally significant in the original GWASs being meta-analyzed, are listed in Supplementary Tables S2 and S3 .

Furthermore, inclusion of additional AD risk loci that were identified to be nominally significant in relation to AD in GWASs may identify a stronger association [ 8 ].

This included nominally significant associations at BRCA2 , CHEK2 , ETAA1 , HROB , HELB , SAMHD1 and ZNF518A .

1 Adding HFH outcomes (number of HFHs and time to first HFH) provided additional discrimination between patients, resulting in more wins with digitoxin at these levels and nominally significant win ratios.

Manganese concentrations were associated with differentially methylated CpGs among infants overall and stratified by sex, most of which were nominally significant in childhood; all metals were associated with at least one differentially methylated region.