Differences in days to silking and days to tasseling were also marginally significant ( P = 0.0303 and 0.0002, respectively), revealing that the QPH1/QPH1 individuals flower slightly earlier.
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Marginally significant after Benjamini-Hochberg correction for multiple testing (corrected p-value = 0.0308) are marked with *.
In this analysis, the loading volume had the largest and statistically significant effect on yield, purity, and resolution ( p = .0186), and the loading concentration had a marginally significant effect ( p = .0309).
Functional in silico analysis of 375 genes affected by protein-altering de novo variants (missense predicted as probably damaging by Polyphen, nonsense, conserved splice site (±2) and frameshift Indels) [20] , [21] , [22] , [23] and this study ( Table S5 ) revealed a marginally significant enrichment for genes involved in cellular component morphogenesis (GOTERM_BP_FAT Gene Ontology, Benjamini p-value = 3.1×10 −2 ) and genes expressed in brain tissues (TISSUE Expression, Benjamini p-value = 5.4×10 −8 ).
The PPSV23 was associated with a marginally significant reduction risk of bacteremic pneumococcal pneumonia in the age subgroup >=60 years (HR: 0.74; 95% CI: 0.56–0.97; p = 0.031) and immunocompetent persons (HR: 0.72; 95% CI: 0.53–0.98; p = 0.035), but no benefits emerged against all pneumococcal pneumonia and/or all-cause pneumonia.
In addition, and according to our hypothesis, the relationship between colony size and body size between body size and the number of individuals in bumblebee colonies resulted negative and marginally significant ( β = −0.217, SE = 0.108, t = −2.001, P = 0.031).
2a ) with a marginally significant change in the level of cell aggregation as shown by the lower change in OD 600 between undisturbed and disturbed cultures (0.88 vs. 0.99, Wilcoxon rank sum P =0.031; for comparison, the non-motile C. difficile IS58 had 1.84-fold change in OD 600 , Fig. 2b ).
However, the sero prevalence between sexes in the Kurunegala district showed a higher prevalence in males, the differences of which were marginally significant for AMA1-Pf ( p = 0.031) and for any Pv ( p = 0.044)/any Pf ( p = 0.045) antibodies (Chi square Test).
168 , 169 The Cochrane meta-analysis (n = 1039) found marginally significant lower 12-month relapse rates with omega-3 fatty acids over placebo (39% vs 47%; RR, 0.77; 95% CI, 0.61–0.98; P = .031).
Notably, the putative MDD risk allele (A) of rs12415800 showed a marginally significant overrepresentation in cases compared with controls (one-tailed p = 0.031, OR = 1.085, Table 1 ).
Following Bonferroni-correction there was a marginally significant interaction between reactivity group and time (age 10 & 12) on left amygdala volume (β=-42.12, p < .031), and the change in the variance explained was significantly greater than the model without the interaction effect (χ 2 (1) = 5.27, p < .022; AIC/BIC without interaction = 1310.3/1336.8; AIC/BIC with interaction = 1307.0/1336.2).
Polygenic risk affects the progression from A+T− to A+T+ The survival analysis showed a marginally significant contribution by APOE-e4 burden (HR = 1.62; 95% CI: 1.05–2.51; P = 0.031), which was mainly driven by APOE-e4 homozygotes (HR = 2.58; 95% CI: 1.05–6.35; P = 0.039) rather than APOE-e4 heterozygotes (HR = 1.74; 95% CI: 0.87–3.49; P = 0.12) ( Fig. 2 ).
Global association was conditioned on rs4522865 and rs10516487, in turn, and the individual effects of the two SNPs remained marginally significant (rs4522865, P =0.031; rs10516487, P =0.047).
Additionally, marginally significant differences are noted in bladder cancer (p=0.031) and bronchus and lung cancer (p=0.044).
Although disease genes show a marginally significant ( p < 0.031) difference in their expression levels compared with non-disease associated genes ( panel A of Fig K in S1 Text ), disease genes have a significantly higher percentage of differentially stable genes, particularly for substance abuse, (mean DS = 0.702, p < 4.7 × 10 − 21 ), psychiatric (DS = 0.675, p < 3.17 × 10 − 17 ), and movement disorders (DS = 0.635, p < 1.21 × 10 − 17 ) ( panel B of Fig K in S1 Text ).
This finding is also supported by the marginally significant association of GA heterozygotes with disease risk in the cases (OR, 0.53; 95%CI, 0.29-0.95; P= 0.031) and in advanced CKD group (OR, 0. 41; 95%CI, 0.19 - 0.87; P=0.018).
A similar pattern was observed for bipolar disorder PGS, though the comparison between G1−/G2+ and G1+/G2+ yielded a marginally significant result (Z = −2.159, P = 0.031).
Even with our SCCA-CC classifier, the survival difference is marginally significant ( P = 0.031, Univariate Cox regression in Table 1 ; P = 0.0387, and log–rank test in Figure 2D ) in the TCGA cohort.
A more detailed examination of β diversity through additive partitioning revealed marginally significant differences in the turnover component in TKB (pseudo-F = 3.04, p = 0.031), where ditches and ponds showed greater heterogeneity due to species replacement compared to rivers ( Supplementary Figure S1a ).
Removing the adult bee mite infestation rate as an explanatory variable for pupal DWV titres shifted the significance to the main treatment effect, which became marginally significant as a result ( F 1, 10 = 6.26; P = 0.0314).
The lunar phase factor was only a marginally significant predictor for the frequency of MEs (negative binomial GLMM: χ 3 2 = 8.824, P = 0.03172).
Subgroup changes in dermal elastin staining area for Group A were not significantly correlated with age ( R 2 = 0.2278; P = .3384), whereas such changes were marginally significant in Group B ( R 2 = 0.723; P = .0319; Figure 4B ).
Within other categories, only alcohol consumers demonstrated a marginally significant relationship (OR = 1.028, 95% CI: 1.002–1.054, P = 0.032).
Comparing absolute antibody concentrations, we found a marginally significant higher concentration of antibodies in the NS cases than in the community controls (0.078 versus 0.059 AU/mL, respectively, p = 0.032, Mann–Whitney U test), yet no difference was found between the NS cases and the household controls (0.078 versus 0.070 AU/mL, respectively, p = 0.260, Mann–Whitney U test).
PD-scores of communities on the PA individuals were significantly higher than those on the HA individuals at a simulated depth of 500 and 1000 sequences and marginally significant at a sequencing depth of 1500 sequences ( p = 0.032, P = 0.043 and p = 0.057, respectively; t -test; Figure 3 ).