Barely Significant
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“marginal significance”

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p=0.07

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

marginal significancep = .0521.0× alphagold
No significant effects were found at 12-months follow-up (T2 vs T0), though the marginal significance of the regression coefficients of social functioning (β = 0.41, p = .052) and psychosocial functioning (β = 0.42, p = .081; Fig. 5 ) indicated a long-term effect of the intervention at T2. 4 Discussion and conclusion 4.1 Discussion The results of this RCT indicate a positive effect of Op Koers Online for adolescents, an online psychosocial group intervention for adolescents with different types of CI: the intervention had a positive effect on disease-related coping skills (use of relaxation, social competence and information seeking) and on HRQoL (social, school, psychosocial and total).
marginal significanceP = 0.0521.0× alphagold
However, this was not the case in the present study, in which the HR of CrCl values of <30 mL/min showed only marginal significance for thromboembolic events in the univariate analysis ( P = 0.052, Table 3 ), though the P -value exceeded 0.30 in the multivariate analysis ( Table 4 ).
marginal significancep = 0.05251.0× alphagold
However, CADD scores of two candidate SNPs (rs10975820 [ KANK1 : R130C19.3 ] and rs4465021 [ KDM4C ]) not identified as lead SNPs, exceeded this threshold (Table 2 ). The Fisher’s exact tests of the lead SNPs comparing the proportions of heterozygous and homozygous alternate genotypes resulted in three of the four lead SNPs being significant ( p < 0.05) and one having a marginal significance ( p = 0.0525) (Table 3 and Online Resource 4 ).
marginal significancep=0.0531.1× alphagold
Post hoc analysis showed that HDL was different between the HP-non-eradicated and HP-eradicated groups with marginal significance (p=0.053 after Bonferroni correction), and BMI was different between the HP-uninfected and HP-eradicated groups (p=0.003) and between the HP-non-eradicated and HP-eradicated groups (p=0.041) ( Supplementary Table 1 ).