Barely Significant
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“marginal significance”

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p=0.07

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

marginal significancep = 0.0521.0× alphagold
36 showed that patients treated with intensive local therapy (defined as en bloc resection, curettage, or RT with BED > 85 Gy) demonstrated significantly better OS ( p = 0.006) for those with solitary bone metastasis, but only marginal significance ( p = 0.052) for those with multiple bone metastases, when compared to those treated with less intensive (RT with BED < 85 Gy) or no therapy.
marginal significanceP = 0.0521.0× alphagold
In another surgical study, the increase of age decreased the DFS, with a hazard ratio of 0.935 with marginal significance ( P = 0.052) [ 17 ], and, in a Japanese study using CCRT in huge FIGO IB–IIB cervical cancers, age less than 48 was an independent poor prognosis factor [ 18 ].
marginal significanceP = 0.0521.0× alphagold
However, this was not the case in the present study, in which the HR of CrCl values of <30 mL/min showed only marginal significance for thromboembolic events in the univariate analysis ( P = 0.052, Table 3 ), though the P -value exceeded 0.30 in the multivariate analysis ( Table 4 ).
marginal significancep = 0.0521.0× alphagold
Tukey HSD post hoc tests revealed that this difference was only significant for the comparison between LMI and HC with an estimated mean difference of 6.41 (SE = 2.29, t(66) = 2.801, p = 0.018), although the comparison between fSBA and HC did show marginal significance (Est = 4.16, SE = 1.75, t(66) = 2.379, p = 0.052).
marginal significancep=0.0521.0× alphagold
The BED 10 higher than 79.2 Gy 10 was the only statistically significant factor for PFS (p=0.043) on the univariate analysis ( Table 2 ), and showed marginal significance on multivariate Cox regression analysis (≥ 79.2 Gy 10 vs. < 79.2 Gy 10 ; HR, 0.597; 95% CI, 0.354 to 1.005; p=0.052). 4.
marginal significancep=0.0521.0× alphagold
Among patients with stage III to IV disease who underwent NAC (n=132), the BRCA mut group showed better PFS with marginal significance than did the BRCA wt group (p=0.052), whereas a similar OS was observed between the two groups (p=0.619) ( S7G - S7I Fig. ).