“marginal significance”

For microsatellite data, all permutations of Bottleneck analyses, except for NWFS, showed evidence of heterozygosity deficiencies (CB showed only marginal significance in this regard) ( Table 2 ).

2b ) and negatively correlated with the mean size of HRC with marginal significance (Fig. 2d ) across all participants.

For example, our data replicate associations between BRCA1/2 LOF with olaparib 14 and cisplatin 15 , as well as between DPYD LOF and 5-fluorouracil 17 , and between WFS1 variants and cisplatin toxicity 16 at marginal significance levels (FDR < 10%, Supplementary Data 3 ).

Partial least squares regression of lipidomic data related to FCS showed that the changes in the top-ranking lipids associate with the increase of adipocyte cell size in obesity ( Figure S3 ). In line with this, triacylglycerols were also elevated in the adipose tissue of obese twins at the marginal significance level false discovery rate (FDR) q <0.1 ( Figure S4 ).

Based on our a priori hypotheses, planned comparisons were conducted to follow up on the interaction effect despite its marginal significance.

The decline in assemblage change at the spatial scale of K = 15 deserves further attention given the marginal significance, despite a small sample size ( n = 15).

Even though when the OAB-dry and OAB-wet subgroups were analyzed separately, some of the results did not achieve statistical significance because of the small sample size, the p -value of many parameters achieved marginal significance ( Table 3 ).

Their volumes in brain tissue were associated but only with marginal significance.

cN positive; p = 0.087) showed marginal significance in OS.

This evidence is conceptually similar to the 5-item per category (i.e., 10 items altogether) group in Table 2 that had a similar effect size but only marginal significance.

The model as such reached only marginal significance.

When examining the different categories of the number of events exposure, neither being exposed to 1–3 events (compared to common exposure) was a significant predictor of probable DSM-5 ASD (OR = 1.56 [95% CI: 0.62; 3.91]) nor was being exposed to 4 + events (which had marginal significance; OR = 2.28 [95% CI: 0.88; 5.92]).

This study is among the first quantitative studies to examine the correlates of child apprehensions among marginalized and stigmatized populations such as sex workers.Our findings lend support to existing qualitative studies that suggest there is a cyclical nature to child apprehensions; sex workers who had been apprehended as a child had 48% increased odds of having their children taken away from them, though this only retained marginal significance when adjusted for other factors in multivariate analysis, suggesting other mechanisms may drive this risk.

In the fully adjusted model (Model 3), this significant negative association was maintained for total BCAAs and valine (both p for trend = 0.03), while marginal significance was observed for isoleucine ( p for trend = 0.05) and leucine ( p for trend = 0.047).

In contrast, the expression of mDNER increased the levels of endogenous DNER (1.37-fold, p = 0.084) and NICD (1.45-fold, p = 0.090) with a marginal significance.

Additionally, FAD and QLQ-C30 scales showed marginal significance, while demographic and lifestyle factors such as gender, age, and smoking history had no significant correlation.

These interpretations should be made with caution given the lack of a significant interaction effect in the overall model and the marginal significance of the Condition main effect.

The HE-RG animals showed higher DMI with marginal significance during the metabolism trial compared to the LE-RG.

A few other interactions between menopausal status and alcohol consumption also showed marginal significance (Additional file 1 : Table S1).

For example, at the current sample size, the variants in the pharmacogenes tested, which showed marginal significance in the targeted analysis, would not have been detected at a stringent genome-wide threshold.

Given the marginal significance of the sex*season interaction, we separately estimated monthly survival for the males and females in the non-breeding season ( φ non-breeding male : 0.8454, 0.8170–0.8701; φ non-breeding female : 0.8526, 0.8236–0.8776), as well as in the breeding season ( φ breeding male : 0.8091, 0.7646–0.8468; φ breeding female : 0.7801, 0.7381–0.8170; Fig. 6a ).

Compared to the breast-fed children, those who were not breast-fed were more likely to become overweight, with marginal significance.

The marginal significance of each selected environmental variable was assessed using permutation tests (function ‘anova.cca’ with 10 000 permutations; ‘vegan’).

Furthermore, electrical tuning is probably of only marginal significance in the upper hearing range of birds (reviewed in [3] , [51] ).

In conclusion, our retrospective analysis in patient with mCRPC, mostly treated in post-docetaxel setting, showed that high Gleason score, lower PSA and LDH levels before starting abiraterone were significantly associated with long-term abiraterone exposure (a marginal significance being found for lower ALP).