Marginal significance was defined as 0.05 < P < .07. 2.6.
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“marginal significance”
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These associations were attenuated to marginal significance after multivariable adjustment (Model 2) and became completely non-significant after further considering the amount of alcohol intake (Model 3).
Such future studies may show robust enrichment of damaging DNMs in genes with marginal significance in this study, such as the 18 candidates that we excluded from the 52 candidates when we selected the 34 plausible ones.
Analysis of clinicopathological parameters in TCGA ACC cohort showed ASXL1 expression was significantly higher in tumors with incomplete removal, with marginal significance in tumors of higher stage and progressed disease upon adjuvant treatment ( Supplementary Table 1 ).
Smoking was also associated with poor self-rated health, although the Cochran-Mantel-Haenszel test showed a marginal significance.
However, because of the marginal significance of interaction and the small number in the CT group with renal dysfunction, we could not definitely conclude that the negative prognostic impact of renal dysfunction could be reduced by appropriately choosing the initial imaging modality.
The Durbin Wu Hausman test indicates no evidence of endogeneity at the 5% significance level; however, marginal significance at the 10 percent level suggests potential endogeneity.
The deviations in the proportions of the AC and AG motifs were of only marginal significance and differed between the enriched libraries, varying with the number of probes: from over- to underrepresentation with increasing number of probes for AG and from non-significant to underrepresentation for AC.
Patients with HR-CTV ≥ 40 cm 3 had worse LC than those with HR-CTV < 40 cm 3 with marginal significance.
After adjusting for age, gender, ethnicity, ideal physical activity, hay fever, and asthma, compared with the reference group (vitamin B 12 with second quartile), the OR for eczema was 0.566 (95% CI: 0.321–1.028, marginal significance) for the first quartile of vitamin B 12.
The significance level was set to 0.05 with two-tailed testing, and marginal significance was defined as a p value between 0.05 and 0.1 [ 38 ].
Marginal significance was shown at earlier time point, i.e.
For male mice, marginal significance was observed for mice fed a vitamin D-deficient diet having earlier tumor onset (Figure 2 B); however, this result was not significant when age of first tumor detection was directly tested (Figure 2 C).
Therefore, findings from subgroup analyses, particularly those with marginal significance, should be interpreted with appropriate caution.
The LightGBM model had a higher AUROC value than the LR-scoring model with marginal significance.
Together with the marginal significance of the enrichment, this result suggests that the alteration of microRNA binding sites is not among the most relevant mechanisms in the genetic determination of 3′ UTR isoform ratios.
For the Affected side, results indicate statistical significance (p-value < 0.05) for MAV of GL, marginal significance for RMS value of both GL and TA muscles.
Taken together, we performed Cox regression with all elements passing significance included in the multivariate analysis and found race, tumor stage, DC being independent prognostic factors, whist ACSM3 remaining marginal significance ( Table 1 ).
In the JSPH cohort, DEL was noticeably associated with a higher ratio of older age ( P = 0.019), elevated serum lactate dehydrogenase (LDH) level ( P = 0.027), and ABC‐like cell of origin ( P = 0.026), while high‐risk IPI ( P = 0.057) showed marginal significance (Table 1 ).
Additionally, after adjusting for the APOE genotype, only marginal significance was found at the cross-sectional level between NfL and CCS (in the whole population and the NC group) while in the MCI group, significant cross-sectional association was found between NfL and DSST-WAISR (β = − 0.04, 95% CI [− 0.07, − 0.01]).
The coefficients associated with being a nurse decrease significantly and maintain only marginal significance.
Similarly, a significant association was observed between wPRS and the DLCN score in the overall cohort, with marginal significance noted in the PCHD and HC groups ( Supplementary Table S2 ).
Time to distant recurrence did not differ significantly by detection method stratified by stage and had marginal significance in distant disease modelling.
The marginal significance of the explanatory terms were then calculated from the reduced model.
Statistical significance of main effects was set at p < 0.05 with p < 0.10 indicating marginal significance.