“highly significant”

Furthermore, among these 2137 samples previously assessed, we confirmed a highly significant association between ddPCR-estimated AMY1A copy number and lower BMI (β = –0.0043 ± 0.0011 kg/m 2 per AMY1A copy, P = 1.7 × 10 −4 ; Additional files 9 and 10 ).

Further, the purple module showed a highly significant positive correlation with POD ( r = 0.77, p = 0.00017), indicating that the accumulation of purple module transcripts was associated with an increase in POD activity.

This established a statistically highly significant association between hyponatremia and hypertriglyceridemia in our ALL cohort (p = 0.00017, Table 2 ).

Disease had a highly significant ( p = 0.00017) impact on cell composition and steroid use was marginally significant ( p = 0.04680).

When data of lepidosaurs, turtles and crocodylians are combined, a weak but statistically highly significant correlation emerges (area: adjusted R 2 = 0.104, p -value = 0.00017, df=120; length: adjusted R 2 = 0.3373, p -value <0.00001, df = 178; Fig. 4 ).

The Pearson correlation of log-transformed variables was weak but statistically highly significant (0.348, p < 0.000171).

This finding was highly significant (P=1.78×10 −4 ) in the combined meta-analysis with a 3.05-fold increase in risk of esophagitis (95% CI=1.70–5.57).

Combined analysis of all samples investigated (2,966 cases, 10,556 comparison subjects) produced highly significant evidence that duplications at 15q13.3 are associated with ADHD (p=0.000178; odds ratio=2.22, 95% confidence interval=1.46–3.38).

In a Δ mutS strain, the protection is stronger and highly significant ( p = 1.8 × 10 −4 , U = 124.0, corresponding to 72% of mutations that are avoided): this is qualitatively consistent with our theoretical prediction that the protection is higher when the mutation spectrum is biased towards frameshifts ( Fig 2 ).

In contrast, V-SO 2 % showed a stronger and highly significant positive correlation with ST V ( r = 0.70, p = 0.00018).

Fisher’s Exact test (two-tailed) on the frequency of LOF and nonsynonymous variants associated with 46,XX DSD observed in our cohort, compared with rare (Minor Allelic Frequency [MAF] < 0.01%) LOF and nonsynonymous variants in the WT1 gene from control individuals, shows a highly significant enrichment of these WT1 variants in the patient cohort ( P < 1.8 × 10 −4 ).

Those associations proved to be highly significant ( p = 0.00018).

This preference was highly significant (binomial test, p = 0.00018).

Using KD data for this gene, we find that there is a highly significant decrease in the cleavage ratio in KD samples compared to controls ( P = 0.00018, one-tailed t -test, mean control ratio = 0.125, mean KD ratio = 0.066, Fig. 3 ), suggesting that RPS19 may be modulating RNA processing at this site.

Control comparison, M6 showed highly significant elevation (FDR-adjusted p = 0.00018), followed by A2BG1S1 (FDR-adjusted p = 0.0062) and M5 (FDR-adjusted p = 0.0296).

The relationship between pH and NF-κB p65 expression was explored by linear regression and a highly significant effect observed [ F (1,5) = 98.3; p = 0.00018; Figure 4 B].

The difference between the decay profile of non-cuticular and cuticle characters is highly significant (Mann-Whitney-Wilcoxon p = 0.00018).

This difference was highly significant ( Figure S5 B, Wilcoxon signed-rank test, p = 0.00018, n = 18 sessions in 2 monkeys), suggesting that the eyes were very stable in the time interval of interest.

Using the mean coverage rate of CLIP-identified mRNA targets (including the flanking 15 nt) as the expected probability to perform a binomial test, we found that the coincidence of 193 predicted piRNA target sites relative to CLIP-identified targets within 169 genes was highly significant ( P = 0.00018).

A one-way ANOVA analysis showed a highly significant effect of origin on CI at the end of the winter conditioning (week 9) (F = 15.95, p = 0.00018).

Conversely, high mortality of STX-exposed eggs was observed in the different replicates, and the hatching percentage was 14 times lower (4.92 ± 0.80%) compared to that of the control group, with the difference being highly significant (Student’s t -test, p = 0.00018; Figure 1 ). 2.2.

The Breusch–Pagan test was highly significant (BP = 13.978, df = 1, p = .0001849), rejecting homoscedasticity (Figure 3b ).

This showed a highly significant positive relationship ( r = 0.83, p = 0.00019) between the two variables.

Log-rank analysis showed a highly significant difference between the two groups ( P = 0.00019), indicating that the CPVI + PLUS strategy was more effective in reducing AF recurrence ( Figure 2K ).

When we considered PI, however, categorized at the cutoff of 2.4, the statistical association was highly significant (p = 0.00019), and we observed discrete values of sensitivity (29.41%) without losing too much in specificity (88.19%).