“highly significant”

The highly significant positive slope ( p < 0.0001) of relative amplitude squared on relative period further strengthens the prediction that coupling is present, as seen in the existing three families of clock models 34 , 35 .

The coefficient ρ, which measures the correlation between the error terms of the two regressions that we jointly estimated in the analysis, was negative (−0.292) and highly significant ( P < 0.0001).

ANOVA results indicated a highly significant model, as demonstrated by an exceptionally high F-value of 644.09 and a low probability value (p-value < 0.0001), underscoring the reliability of the developed model (Table 5 ).

RML-inoculated transgenic mice reached terminal disease after 400 ± 56 dpi (n = 10), whereas WTPrP C mice became terminally sick at 155 ± 1.6 dpi (n = 8), thus also showing a highly significant delay for PrP C GPIThy-1-expressing mice (Log Rank (Mantel-Cox)**** p <0.0001; S6A Fig ).

Group 2 showed highly significant difference in leakage values in comparison to group 1 ( P value<.0001).

The survival difference between ST-positive and ST-negative is highly significant ( P < 0.0001, log rank test).

There was a highly significant improvement ( P ≤ 0.0001) for all of the efficacy variables in oclacitinib-treated dogs compared with placebo-treated dogs.

Both single and average intra-class correlations of each country were highly significant ( p < 0.0001), but the averaged seasonal data demonstrated higher reliabilities than individual data, as seen from larger correlation coefficients (Table 3 ).

Results: Natalizumab patients had a net improvement in disability over time (-0.15 EDSS years) while placebo had a net worsening (+0.33 EDSS years), as measured by LS mean AUC; the difference (0.48 EDSS years) was highly significant ( P < 0.0001).

There was a highly significant association between the increased use of elastin staining and a perceived increase in VI detection ( p < 0.0001).

Highly significant differences between adjacent and tumor tissues were found by statistical analysis using the Mann–Whitney U test ( p < 0.0001 for all comparisons; Figure 2 A–C).

Likewise, the 10-mm diffusion tip with 15 W power yielded a highly significant correlation (r = 0.995, p < 0.0001).

Maxillary central incisors were the most commonly impacted teeth with a prevalence rate reported at 78.8%, while the results were found to be statistically highly significant when compared between maxillary and mandibular teeth ( P = 0.0001) [ Table 3 ].

This difference was highly significant (p < 10 −4 , Kolmogorov–Smirnov test).

There was a highly significant correlation of serum and saliva scores ( P < 0.0001) and the Spearman correlation coefficient of ρ = 0.602 indicated a moderate positive correlation [ 34 ].

The number of eggs in the cluster had a highly significant positive effect on water percentage ( F 1,16 = 31.43, p < 0.0001).

Results The Dutch breeding bird fauna, as well as all habitat communities underwent highly significant directional change ( p <0.0001) between 1984 and 2009 ( Figure 2 ).

Kaplan-Meier analysis was not possible in the 74 week group since no z_Q175 homozygous animals acquired the response within the available timeframe (also note the small n in this cohort) but analysis of the 53 week animals confirmed that there were highly significant differences amongst the groups, Logrank (Mantel-Cox) χ 2( 2 ) = 32.8, p < 0.0001 .

At MWU, a highly significant variation ( P < 0 0. 0001) in PDS was observed among the wheat lines and ‘Maddawalabu’ ( Table 2 ).

The difference in pCR rates between TIL-high and TIL-low patients was highly significant in univariate analysis ( P < 0.0001; OR, 6.325; 95% CI, 2.487 to 16.08; Table 2 ).

RESULTS: The statistical evaluation demonstrated that QOL presented highly significant statistical dependence on femoral and popliteal PTBA (p < 0.0001).

For MZ twins, the association between twins’ attachment security was highly significant (kappa = .26, χ 2 (1) = 19.86, p < .0001).

Those shifts ranged from a modest four-percentage-point increase in support of legalization to a substantial 12-point jump in the share who said it us “safe for pit bulls to live in residential neighborhoods.” The differences in percentages from 2014 to 2018 for the first three questions in Figure 1 are all highly significant ( p < 0.0001), while the four-point difference in support for legalization shown in the final column of the figure is marginally significant ( p = 0.06).

A full factorial ANOVA revealed that all four factors were highly significant in their impact on children's understanding of complex sentences ( p ≤ 0.0001).

Our model results showed a highly significant interaction (χ 2 = 94.3, P < .0001) [ 27 ], confirming a difference in patterns of deferral by CD4 count and patient type.