There was a highly significant difference between LAP level in compliant and non-compliant patients (1.045 ± 1.270 vs. 0.0785 ± 0.1057 ng/ml, respectively, p value < 0.0001).
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Screens of 11 known antibiotics and other drugs revealed that Fexinidazole, Corallopyronin A and Rapamycin reduced the number of Wolbachia clusters infecting sheath cells but only Fexinidazole and Corallopyronin A showed a highly significant difference (p < 0.0001) compared to the control group.
Both measurement systems showed that germ cell number and percentage immunostained area decreased by approximately 2, 3 and 20 fold in the groups treated with the highest SN38 concentration compared with control, demonstrating a highly significant correlation between the two methods ( r = 0.954, p < 0.0001; Fig. 2 C).
There was a highly significant increase in the incidence of secretor status in O blood group individuals when compared with A, B, and AB blood group individuals separately ( P < 0.0001, P < 0.0001, P = 0.0003, respectively) and collectively ( P < 0.0001).
This difference was highly significant ( P < .0001).
5 , N = 102 patients) revealed highly significant differences in SOZ and non‐SOZ channels ( P < 0.0001; Wilcoxon rank sum) in aggregate and in individual epilepsy patients ( N = 90, P < 0.0001, Sign test).
Although this might be indicative of a small population of cells which are unspecifically stained by the melan-A antibody, a highly significant ( P < .0001) correlation between the number of melan-A positive cells and microscopic pigmentation in the melanin staining was observed ( Figure 1(a) ).
146.22 ± 41.84 mL/min/100 g, p < 0.008), showing a highly significant correlation with GFR in all subjects (r = 0.75, p < 0.0001).
Among LAC patients with additional tissue section available for next-generation sequencing (NGS)-based analysis, 26/193 (13.5%) patients found positive for even low-rate EGFR-T790M mutated alleles at baseline were associated with a highly significant lower survival in comparison to those without (8.7 vs. 47.4 months, p < 0.0001).
This difference is highly significant ( t = −4.41, p < 0.0001) and depends on the fact that differences between motor patterns resulted very salient, whereas it was more difficult to distinguish hand postures.
A direct comparison of pre- and post-vaccination titers of neutralizing antibodies clearly confirms a highly significant increase in both groups (p < 0.0001).
Results Relationship between Maternal LOC and IQ at 8 The unadjusted difference between the mean IQ of 8-year-old children whose mothers were external compared to those who were internally oriented showed deficits of 7.33, 5.29, and 7.23 IQ points for the verbal, performance and full IQ scales, respectively ( Table 2 ); each was highly significant ( P < 0.0001).
Whereas the density of pancreatic stellate cells (PSCs) was not different in tissues isolated from control and FAEE-AP (72 h) mice ( n = 14 and n = 31, P > 0.54), the density of PMs increased significantly in FAAE-AP mice after 48 h ( P < 0.033) and was highly significant after 72 h ( P < 0.0001; Figure 2E, F ).
One-way ANOVA followed by Tukey ’ s test demonstrated that the enrichment of TcIT in PM with respect to HG (160%) and TM (130%) was highly significant ( P < 0.0001 and P = 0.0001, respectively).
The quadratic terms (A 2 , B 2 , C 2 , D 2 ) and interaction terms (AB, AC, BD, CD) were highly significant ( p < 0.0001), while BC was significant at the p < 0.01 level ( Table 5 ).
Under supplementation with 5 mM L-Trp, the IAA yield increased to 6.01 ± 0.15 μg/mL, representing a 274% enhancement, which was statistically highly significant ( p < 0.0001) ( Figure 8 C).
The prevalence of LBP was highly significant (p < .0001) among girls (confidence interval [CI]: 1.5 to 3.2; OR: 2.2), those who felt their school satchel was heavy (CI: 1.7 to 3.5; OR: 2.4) and those who watched television (TV; CI: 0.03 to 0.28; OR: 0.09).
Twelve minutes after adding the drug significant (P<0.01) differences were detected between motility of sensitive and resistant lines, and from 6 hours onwards the difference was highly significant (P<0.0001).
Spearman’s correlation analysis revealed a highly significant association between the WOMAC total score and the CSI score (rho = 0.791, p < 0.0001), the PDQ score (rho = 0.766, p < 0.0001), and the PCS score (rho = 0.536, p < 0.0001) ( Table 2 ) ( Figure 3 ). 3.3.
In lung adenocarcinoma, the most predictive signature generated from the Kim and colleagues ( 38 ) dataset revealed no association with survival when derived from ldvae [ P = 0.25 or −log 10 ( P ) = 0.6], whereas the BBKNN signature showed a highly significant predictive capacity [ P = 1e−4 or −log 10 ( P ) = 4; Fig. 5B ].
Postoperative VAS scores were statistically highly significant for the first 4 h in control group compared with the adjuvant groups ( P < 0.0001) [ Table 3 ].
Statistical analysis revealed that the differences in prevalence between the two time periods were highly significant for all three allergens: thiuram mix ( χ 2 = 1382.26, p < 0.0001), mercapto mix ( χ 2 = 179.58, p < 0.0001), and mercaptobenzothiazole ( χ 2 = 317.21, p < 0.0001). 3.2.4.
The chi-square test revealed a highly significant association (χ 2 = 121.85, p < 0.0001) between the period (flowering scarcity vs. flowering onset) and the eversion of the copulatory apparatus.
Inclisiran produced a mean LDL-C reduction of −46.5% at day 150 versus +1.4% with placebo and −11.2% with ezetimibe; the between-group differences were large and highly significant (inclisiran vs. placebo −47.9%, and vs. ezetimibe −35.4%; P < 0.0001 for both comparisons) [ 30 ].
Using a more sophisticated haplotype-based method (focusing on ∼21% of the genome), we found 24 highly significant ( P < 0.0001) haplotype blocks suggestive of selective sweeps.