Results: We found a highly significant reduction of circulating pDCs ( p < 0.0001) and in bone marrow ( p < 0.0001) of MM patients compared to HD.
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The use of mifepristone showed a reduction in the use of oxytocin (RR = 0.84; 95% CI: 0.70–1.01), although this difference did not reach statistical significance ( p = 0.065), and a highly significant reduction in prostaglandin use (42.7% vs. 78.9%; RR = 0.54; 95% CI: 0.48–0.60; p < 0.0001), with no significant difference in cesarean section rate (18.9% vs. 23.6%; RR = 0.80; 95% CI: 0.63–1.01; p = 0.068).
In addition, there was a highly significant negative linear correlation between the N% and C/N ( P < 0.0001, R 2 = 0.8844).
The highly significant p values ( p < 0.0001) showed that there was a significant change in mean value from baseline for all three variables.
Results: Our primary outcome was changes in pre-treatment opioid craving scale (OCS) minus baseline, and we found using a mixed model that the active group had a highly significant treatment * time benefit over the sham group, p < 0.0001, effect size at the last follow-up of 1.5.
The gene expression analysis showed highly significant up-regulation in FLT3 of all AML samples [FLT3-wildtype (0.316 ± 0.05 folds) and FLT3-mutants (0.368 ± 0.03 folds)] in contrast of control group (P = 0.0001).
The results show a highly significant CONNECTIVE × EADV interaction (LRT = 56.92, p < 0.0001), see Table 6 and Figure 3 .
A highly significant difference ( P < 0.0001) was found.
As the prevalence of ESBL went from 3.78% to 50.80%, it increased 13.4-fold between 2003-2005 and 2018-2019, thus amounting to a highly significant increase (p < 10-4).
sylvestris was highly significant ( p < 0.0001: ****).
In comparison, the well-developed t-tubule network staining of ventricular myocytes occupied 6.945±0.395% of the cell cytoplasm ( Fig 4Aii ) ( n = 24) which was highly significant (P<0.0001).
When comparing the overall results, a highly significant antiproliferative effect of chloroquine was observed with both concentrations of chloroquine compared to untreated control cultures ( p -value < 0.0001, Mann–Whitney U-test; Figure 2 ).
Stunting was highly significant in both models ( p -value < 0.0001), with small, positive coefficients ( β HAZ 2 = 0.23 for MUACZ2 and β HAZ 2 = 0.14 for MUAC125).
allopatric) and recipient pond, was highly significant ( X2 = 57.9, df = 23, p < 0.0001; Table SI 4 ).
Note that MFI is displayed on a logarithmic scale, and the effect of all three anti-cytokine antibodies was highly significant (p < 0.0001) for IFN-γ.
As shown in Figure 5 C, the results of specificity testing using a double-antibody sandwich ELISA indicated that, compared with the blank control, the assay had a highly significant ability to detect the SARS-CoV-2 N protein ( p < 0.0001).
The P values remained highly significant for NRS ( P <0.0001), VAS ( P <0.0001), BPI-MSF ( P = 0.001), and PDQ ( P = 0.02), while the P values for ≥30% pain reduction ( P = 0.27) and ≥50% pain reduction ( P = 0.02) were also consistent with the primary analyses.
When the analysis was performed according to the lesion size, a statistically significant difference was noted in the detection rate of DWI and T 2 -TSE for both types of metastatic lesions (lesions with size <10 mm and lesions with size >10 mm), and the difference was highly significant ( p < 0.0001) for lesions <10 mm in which DWI detected 38 more lesions compared with T 2 -TSE.
The deviations between the torsional spaces covered are highly significant for almost all maps (p-value < 0.0001), with significantly higher mean distance-to-centroid for all MD maps (see also Additional file 1 : Table S4).
Temperature effects on mycelial growth of different Fusarium species According to ANOVA, the average effects of different temperatures on fungal radial growth of Fusarium species were highly significant at P < 0 . 0001 .
The increase remained to be highly significant after exclusion of patients with 0 MUT gene from the MUT low group ( P < .0001 for KMT2D mutations in all comparisons).
The difference was also highly significant between CD patients on GFD and those with active disease ( p < 0.0001).
The two-way interaction of the condition and the surface was also highly significant ( p -value < 0.0001), indicating that polishing increased the microhardness values at the top and the bottom surface.
The results show that there is indeed a highly significant negative correlation (correlation coefficient R 2 = 0.87; P = 1 × 10 −04 ) between the degree of nucleotide bias and the d N/ d S ratio (see fig. 2 a ).
When also two studies with calcifediol were considered, the effect on PTH was highly significant ( P < 0.0001), but heterogeneity was substantial ( I 2 = 60%) (not shown).