“highly significant”

4 B) have sampling distributions that overlap for H3N2 and H1N1 (all years), while the same distributions for prepandemic H1N1 do not, hereby showing that the shift in H1N1 connectivity network is highly significant (with 10 5 replicates: P < 10 −5 ).

Interestingly, we found that the ASA difference between functionally critical and non-critical sites involved in catalytic or binding activity in our data set is not statistically significant ( P > 0.08), whereas the difference of dfi between these sites is highly significant with P < 0.00001 as also shown for residues located in loops ( Fig. 3 B).

There was a statistically highly significant ( P < .00001) association between low serum zinc levels and WHC grades of HE.

Heterogeneity analysis revealed highly significant heterogeneity (I 2 = 93%, p < 0.00001), thus a random-effect model was used for statistical analysis.

We searched for differentially methylated regions (DMR) where 100 adjacent CpG sites on the BeadChip are regulated accordingly—only two genomic regions revealed such a highly significant enrichment of SA-DNAm changes ( P < 10 −5 ): the HOXB locus on chromosome 17 (SA-hypermethylated) and the keratin associated protein (KRTAP) locus on chromosome 21 (SA-hypomethylated; Supplemental Fig. 3).

The pooled effect size of PPD between the CP plus T2DM vs healthy group was revealed to be highly significant with quite a large effect size [SMD = 5.29 (95 % CI: 4.58 to 6.00); p < 0.00001; I 2 = 52 %) ( Fig. 6 ).

Similarly, Table 3 shows the multiple comparison using Dunn’s multiple comparison test with the results being fairly significant ( p < 0.001) for the Watch–Access pair, very highly significant ( p < 0.00001) for the Watch anti-TB without duplicates pair, and highly significant ( p < 0.0001) for the Watch anti-TB (all) pair.

Table 2 shows the intergroup and intragroup comparisons between Group A and Group D using one-way analysis of variance wherein a significant difference was observed between all four groups when intergroup and intragroup comparisons were made, while the results were found to be statistically highly significant ( P < .00001).

For IL6 at the basal level the differences between S1L4 and N1L4 were highly significant (6.9-fold increase in N1L4; p < 0.00001).

Genetic structure was highly structured among these groups of populations (AMOVA; permutation tests highly significant, P <0.00001), meaning that most of the genetic variability was partitioned among groups (77.28%), and only a small proportion of the variability was partitioned among populations within groups (14.71%) or within populations (8.003%).

Testing for heterogeneity showed a highly significant result (p<0.00001) and high inconsistency (I 2 = 94%).

Therefore, there is a highly significant difference in the expression of functional GABA B receptors on VTA GABA neurons compared to VTA dopamine neurons ( P <0.00001, Fisher exact test), making this property the most reliable pharmacological difference between GABAergic and dopaminergic VTA populations.

When comparing each variable (GI35, GI42 and DTF) between years (Figure 2b–d ), highly significant correlations were observed ( P < 0.00001) supporting a strong genetic control of these traits.

Inter-rater reliability was highly significant (Cohen's κ = 0.62; Z = 19.1; P << 0.00001; number of errors = 90).

The overall model was highly significant (chi 2 = 108.2, df = 2, p<0.00001).

Mander’s overlap coefficient also showed a strong increase (>0.7), indicating that the majority of autofluorescent signal colocalized with mitochondrial structures under high-dose conditions. Statistical analysis on Pearson’s r coefficient using one-way ANOVA revealed highly significant group differences across all three conditions: AF-DAPI ( F (2,66) = 139.52, **** p < 0.00001), AF-MitoTracker ( F (2,68) = 28.68, **** p < 0.0001), and DAPI-MitoTracker ( F (2,66) = 36.53, **** p < 0.0001).

In contrast, cerebrospinal fluid (CSF) volume showed a significant increase in the full penetrance group (≥40 CAG repeats) compared to the normal repeat group (≤26 CAG repeats), with a highly significant p value (*** p < 0.00001).

The detected linkage disequilibrium was highly significant in both cases (P<10 −5 ).

The frequencies of white choices in S1 and S2 showed a highly significant difference between sessions (χ 2 = 272.23, P <0.00001).

If these studies are added to the pooled analysis, the increased bleeding risk for anticoagulated abdominoplasty patients becomes highly significant ( P < 0.00001). 59 Restifo 12 reported that chemoprophylaxis increased the risk of bleeding “dramatically,” to 4.4%.

21 We performed a meta-analysis of the two studies, which yielded highly significant evidence for association (odds ratio 0.77 95% confidence interval 0.69–0.87, P =1 × 10 −5 ) with no evidence for heterogeneity between the two cohorts ( P =0.81).

All hallmarks showed highly significant differences (adjusted p < 10e-6), indicating robust biological distinctions.

There was a highly significant difference between CT and T2 scores ( P < .00001) and between T1 and T2 scores ( P < .00001).

The χ 2 results show that likelihood ratio statistics are highly significant ( P < 00001) suggesting that the model has a strong explanatory power.

Pairwise F ST analysis showed highly significant differentiation between the IbA10G2 subtype and non-IbA10G2 subtypes at 4 loci around gp60, C6–1000′ (p<0.00001), gp60 (p<0.00001), CP47 (p<0.00001), and C6–2600 (p<0.001).