Interestingly, although APG treatment led to an increase in ATP levels and a decrease in ATPase levels in comparison to the control group, these changes did not reach statistical significance ( Figures 6D, E , P < 0.05). 3.6 APG improves inflammation and oxidative stress in ischemic stroke The levels of MDA, IL1β, and IL6 were markedly increased, while the activities of SOD and GSH were notably decreased in the ischemic penumbra tissue of the MCAO group in contrast to the control group ( P < 0.05).
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In the literature
examined CD25 expression in 88 pediatric ALK+ ALCL patients in a univariate analysis and found that patients with high CD25 ALK+ ALCL tended to have lower 5-year overall survival (OS) compared with those with low CD25 ALK+ ALCL; however, this difference did not reach statistical significance ( p = 0.05) [ 25 ].
VLDL was more rapidly cleared from the plasma after injection to double KO than to ApoE KO mice; this difference, however, did not reach statistical significance ( P < 0.05 n = 6 per group) (Fig. 3 e).
Both PSI ICP and PSI B4C were the highest in patients after craniectomy, with PSI ICP being higher than PSI B4C , although this difference did not reach statistical significance ( p = 0.05) (see Fig. 4 ).
For the development of CKD ≥ stage 2 alone, the difference between cats that were borderline proteinuric vs nonproteinuric at baseline approached but did not reach statistical significance (log‐rank P = .05).
The between-group difference in Nesfatin-1 levels at week 12 approached but did not reach statistical significance ( P = 0.050).
Feeling that avoiding pregnancy was not at all important and correct knowledge of the approximate fertile time were associated with an elevated odds ratio in bivariate analysis but did not reach statistical significance at P ≤.05 in multivariable analysis.
Consistent with our previous results, iPSC-derived SNs with WT FUS showed a trend toward decreased tracing over time, which did not reach statistical significance ( Supplementary Figures S2C,D ). iPSC-derived SNs with P525L FUS-eGFP showed a 5-fold decrease in tracing ( p < 0.05, 2way ANOVA, Sidak post-test for multiple comparisons; Supplementary Figures S2C,D ), consistent with the age-dependent neurodegeneration observed in ALS.
Only converters had annualized decrease in MV thickness before conversion to SPMS of −0.04 ± 0.01 mm 3 /y ( p = 0.001), but the difference between groups for MV change did not reach statistical significance ( p = 0.05).
However, in the postgroup, the higher lung cancer detection rate on the follow-up screens did not reach statistical significance [post: baseline vs. follow-up 0.9% (17/1966) vs. 0% (0/420), P =0.05].
In a 12-month, double-blind, randomised, placebo-controlled trial (VIDOMA trial), we previously found evidence for a greater improvement with omega-3 LCPUFA with or without vitamin D in social interaction in children with ASD compared with placebo but the difference did not reach statistical significance ( P < 0.05) for most comparisons.
The diameter decrease was less than 0.2 mm, comparable to the diameter change from cluster to gap and did not reach statistical significance ( p < 0.05) until the rate was 0.45 ml/min.
showed a trendp > 0.05
Although inflammatory markers such as tumor necrosis factor-alpha (TNF- α ), interleukin-6 (IL-6), and C-reactive protein (CRP) showed a trend toward elevation in SAE patients, these differences did not reach statistical significance ( p > 0.05, Supplementary Table S2 ).
In addition, epidermal consumption (p = 0.07) and increased mitotic activity (p = 0.05) were more frequent in cases with homozygous 9p21 deletion, but these differences did not reach statistical significance. When the clinical features were considered, there was a statistically significant correlation between 9p21 FISH positivity and the diameter (p < 0.05).
did not reach statistical significancep -value < 0.05
Overall, the G3 group had high microbial richness and low evenness; however, this finding did not reach statistical significance ( q < 0.05) in the pair-wise comparison, except for the observed features, although they showed an unadjusted p -value < 0.05.
For example, the absolute median scores regarding anxious and depressed mood were worse in the kinesiophobic patients at T2 but the worse gradings did not reach statistical significance ( P = .05, P = .71) at a 5% significance level.
Negative sensory descriptors such as musty or earthy odor and taste were minimally perceived and did not reach statistical significance (p < 0.05).
365 U/L in males, P=0.07) in female patients, although these differences did not reach statistical significance at the P<0.05 threshold.
Inhalation of salbutamol at equimolar concentrations as salmeterol also reduced TNFα in lung homogenates and BALF 6 h after infection with NTHi although in lung homogenates the difference with vehicle did not reach statistical significance (figure 2B and 2C : p < 0.05 versus vehicle in BALF).
In the verification cohort (cohort II), the difference in mean serum HSP60 concentration between stage I patients and healthy controls did not reach statistical significance, and the difference was barely significant between stage II patients and controls ( P < 0.05).
Following heparin administration, serum HP levels increased significantly ( p < 0.05), while MK and PTN levels showed a decreasing trend that did not reach statistical significance ( p > 0.05).
Findings reported in Table 3 indicate that living in a yellowlined area in 2017 was positively associated with NDI relative to green – and bluelined areas ( β = 0.80, p = 0.00); living in redlined areas trended in the expected direction but did not reach statistical significance at the p < 0.05 level ( β = −0.65, p = 0.08).
However, this trend did not reach statistical significance ( p < 0.05).
For autistic subjects, activation in left inferior frontal gyrus did not reach statistical significance, even at the lowest threshold of P < 0.05 ( Fig. 2 A and Supplementary Table 1 ).
While a numerical trend suggested less deterioration in the intervention group compared to the control group, the differences did not reach statistical significance ( P > 0.05).