We found mild repression of luciferase activity by individual miRNAs, which did not reach statistical significance, whereas the transfection with all three miRNAs resulted in approximately a 60% decrease in activity, suggesting that they act cooperatively ( P <0.05, n =3) ( Figure 2a ).
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Intracoronary injection showed a trend towards improved LVDP but did not reach statistical significance (LVDP: after EPC-TX 128.9 ± 14.7 mmHg versus LV-SDF-1-EPC 121.1 ± 24.5 mmHg versus control 111.8 ± 19.4 mmHg, P < 0.05, Fig. 5 B).
Although there was a decreasing trend in the IRS-1 mRNA expression level in cells transfected with miR-126 mimic, it did not reach statistical significance between the two groups tested ( P >0.05) ( Figure 3B ).
Patients with a preoperative sensory deficit tended to more frequently develop a new postoperative sensory deficit, but this did not reach statistical significance ( p = 0.05; Table 2 ).
In addition, interactions with treatment-by-time and treatment-by-time squared did not reach statistical significance at P < 0.05.
Main effects of “load” [ F (2, 78) = 1.28, p = 0.283], “gender” [ F (1, 39) = 1.83, p = 0.184] and “education” [ F (1, 39) = 1.29, p = 0.263] as well as the interaction effects “load” × “age” [ F (2, 78) = 1.51, p = 0.227], “load” × “gender” [ F (2, 78) = 2.18, p = 0.120] and “load” × “education” [ F (2, 78) = 0.78, p = 0.461] did not reach statistical significance at p < 0.05.
Although, repeated measure ANOVAs did not reach statistical significance, area under the curve (AUC) of insulin secretion per islet was increased in HF islets ( p <0.05).
However, unlike in the β-arrestin-2 interaction assay where the effect of these mutants did not reach statistical significance, in the Ca 2+ assay both N215A 5.46 ( p < 0.05) and T119A 3.33 ( p < 0.001) produced significant reductions in potency for GW9508 compared with wild type FFA4.
Similar to the trap collections, human landing collections in the village were higher than in the plantation, though this difference did not reach statistical significance (F-value = 2.16, p = 0.05).
GS and dose were the most predictive factors in multivariate analysis but did not reach statistical significance at the p < 0.05 level.
Knock-down of PSMD9 significantly sensitized both cell lines to all doses of radiation (p < 0.05; except MCF7 cells at 4 Gy and MDA-MB-231 at 8 Gy, which did not reach statistical significance).
In contrast, naïve CD8 T cells from old adults showed an increase of CCL4 mRNA after activation but did not reach statistical significance, as well as a reduction of miR-125b after activation which was only significant at 48 h ( P < 0.05).
It was concluded that the observed trends between VEGF-2578C/A and K ss or VEGF-634G/C and K ss did not reach statistical significance as the required drop in OFV after the inclusion of VEGF-2578C/A or VEGF-634G/C was 6.8 points or 6.7 points, respectively ( p < 0.05, forward inclusion of one parameter).
Eleven variables were retained for the multiple regression analysis and further variables then removed if their association with the FHSQ footwear domain score did not reach statistical significance (p < 0.05).
However, this trend did not reach statistical significance ( p < 0.05).
All the patients with a number of involved levels ≤2 [ Table 1 ] reported a stable or improved clinical outcome at follow-up but this data did not reach statistical significance on the analysis ( P = 0.05).
The decrease seen in medication infusion discrepancies did not reach statistical significance ( p = 0.05).
Among the eleven remaining patients not on lipid-lowering therapy, there was a trend to an increase in mean LDL and cholesterol/HDL ratio in the first 3 months after TCZ was initiated, although this did not reach statistical significance of P <0.05.
Furthermore, miR‐194‐positive patients have longer overall survival, although this did not reach statistical significance(HR = 0.44, 95% CI = 0.19–1.00, P = 0.05).
While a comparison of ATP and PCr concentrations did not reach statistical significance, PCr/ATP ratios were significantly reduced in the uremic group compared to those in control animals ( P <0.05, two-tailed Mann–Whitney test, Figure 2C ).
A similar trend was observed for the plantaris muscle compared to the B6 strain albeit it did not reach statistical significance ( p = 0.05).
showed a trendP = 0.050
Limited Nesting Stress from Post-natal Days 2–10 Increased Plasma Corticosterone Levels in Pups at Weaning In PND21 males, plasma corticosterone values showed a trend to be higher in LNS group compared to CTL which did not reach statistical significance (4.0 ± 0.4 μg/dL vs 2.4 ± 0.7 μg/dL, P = 0.050, n = 8–9) ( Fig. 1A ).
Nodal metastases were diagnosed more frequently in patients submitted to eLND as compared to lLND; however, the difference did not reach statistical significance (30.8% vs. 26.8%, RR 1.15, p <0.05).
Site of onset did not reach statistical significance ( p < 0.05), but met the criteria required for inclusion in the logistic regression model (Fisher's p = 0.082; Table 4 ).
The increase of MMP9 did not reach statistical significance for T cells (p = 0.05, paired t-test for median fluoresecence intensity – MFI) nor did the increase of MMP2 for AdMSC (p = 0.07, paired t-test for the percentage of positive AdMSC).