“did not reach statistical significance”

Notably, FH patients with Lp(a) > 50 mg/dL showed a trend toward higher 5-year CVD risk scores, although this did not reach statistical significance In addition, a positive association has been reported between CCS and Lp(a) in population studies among people who have not yet developed a coronary event [24] .

Although the difference between pre-therapy and follow-up did not reach statistical significance ( p = 0.086), the results showed a trend toward improvement, suggesting a potential effect of the maintenance protocol in the incontinence domain when evaluated 30 days after the end of treatment.

While several studies did not reach statistical significance, 26 – 28 most showed a trend toward positive change. 29 – 31 These non-significant findings are likely attributable to small sample sizes, limited statistical power, and variability in intervention protocols.

Length of hospital stay and cost considerations Although differences in length of hospital stay among the three treatments did not reach statistical significance, antibiotic therapy showed a trend toward shorter stays.

While the findings showed a trend toward reduced BP with low‐dose TZ, they did not reach statistical significance.

The APOE ε4 variant (rs429358) showed a trend toward higher minor allele frequency in females compared to males (23.7% vs 15.8% combined heterozygous and homozygous carriers) (1a), though this difference did not reach statistical significance (P=0.52).

First, patients who received 6 or more vaccine doses showed a trend toward improved survival (MST 18 months) compared to those receiving fewer doses (MST 17 months), although this difference did not reach statistical significance ( P = .39).

Although the result was close to the significance level, indicating a possible trend, it did not reach statistical significance.

OS in patients with H1047 kinase domain mutation showed a trend toward being shorter compared to others, though this difference did not reach statistical significance.

Sample size and statistical power insufficiency Subgroup analyses of patients with CVD and chronic kidney disease (CKD) showed a trend toward increased mortality in the transfusion threshold <7 g/dL group; however, some results did not reach statistical significance.

Although Hispanic patients also showed a trend toward lower rates of IP arthroplasty, this finding did not reach statistical significance (OR, 0.83; 95% CI, 0.61–1.13).

Although the differences did not reach statistical significance, the higher maximum temperature ( P = 0.059) and relative humidity ( P = 0.499) observed in 2023 suggest a possible trend toward climatic conditions conducive to dengue transmission.

Latent VZV load had an increasing trend according to age, but this trend did not reach statistical significance.

Other domains, such as SRS Function and Mental Health, and the total SRS-22r score showed a trend toward lower values in SK patients, but did not reach statistical significance.

Association between physical activity and cognitive function While the decline in composite cognitive performance from baseline to follow-up did not reach statistical significance ( P = 0.635), we observed a nonsignificant trend toward group-level cognitive decline.

(2021) approached significance, indicating a potential parallel in gene expression patterns, though these trends did not reach statistical significance.

Among men, a significant trend was observed in riboflavin intake below the EAR across frailty groups (p for trend = 0.0250), although the odds ratio for the frail group (ORs: 1.23, 95% CI: 0.99–1.54) did not reach statistical significance.

For severe disability, the multivariable model achieved an AUC of 0.854 versus 0.619 for the univariable model; the difference showed a trend but did not reach statistical significance ( P = 0.088).

In this subgroup, both model-calculated and human-generated LBL showed a trend of being longer in the constipation group when corrected for height or height squared, though the difference did not reach statistical significance ( p = 0.09–0.18) (Supplementary Table 3 ).

ALDH1A2 expression showed a trend toward reduced OS but did not reach statistical significance in the overall AML cohort (P = 0.08), nor in the chemotherapy‐treated (P = 0.09) or relapsed/refractory subgroups (P = 0.2) (Supporting Information S10: Figure 1 ; Supporting Information S2: Table 2 ).

While total EGFR and ERK protein levels showed a decreasing trend, these changes did not reach statistical significance ( Figure 7 G).

Notably, Tagln2 showed a trend toward increased expression, although this did not reach statistical significance.

Tumors from anti–PD-1/anti-MIF–treated mice showed a trend toward more CD3 + and CD8 + T cells, fewer CD163 + (M2) macrophages, and higher CD8/CD3 ratios that did not reach statistical significance.

Interestingly, C20:1n-9 showed a trend toward being more abundant in the hind limb muscle of males, although this did not reach statistical significance ( p = 0.074), as well as C10:0 and C12:0 ( p = 0.060 and 0.087, respectively).

At 60-day post-surgery (Table 1 ), while absolute bone volume (BV) showed a trend toward higher values in the HMTs–CHS group (13.92 ± 1.36 mm 3 ) compared to CHS (11.12 ± 2.71 mm 3 ) and blank groups (10.28 ± 1.41 mm 3 ), this difference did not reach statistical significance ( p = 0.060).