“did not reach statistical significance”

Age 3–17 years, tumor volume >8 cm3, and KPS 70–90 showed a trend toward association, but the differences did not reach statistical significance (HR = 2.01, p = 0.095; HR = 2.46, p = 0.087; HR = 0.50, p = 0.111) ( Figure 4 , Table 6 ).

IMP4 was significantly upregulated in GSE66407 , whereas it showed a decreasing trend in GSE179285 and GSE11223 , although the differences did not reach statistical significance ( Figure 4C ).

The study showed a trend toward reduced cognitive decline, although results did not reach statistical significance.

GB102 showed a trend toward reduction in HFD-induced leptin levels, although this effect did not reach statistical significance.

A positive trend in daytime functioning was observed upon chamomile consumption, though it did not reach statistical significance. 142 By contrast, 2 methodologically identical studies in 77 elderly hospitalized individuals with a mean age of 74.3 ± 10.6 years, 143 and 110 postmenopausal women aged 50-60 years, 144 found that 400 mg of chamomile extract twice a day for 4 weeks significantly improved PSQI sleep scores following treatment (from 8.8 ± 4.3 to 5.0 ± 3.7, P < .001, and from 13.68 ± 1.68 to 9.07 ± 1.53, P = .001, respectively) compared to placebo.

Specifically, the odds of macrosomia were markedly elevated among women with early menarche, declined to the lowest level at the reference age, and then showed a positive trend of increasing risk with AAM values greater than 15 years, although this association did not reach statistical significance at the individual later age points.

After propensity score matching, the association was attenuated and did not reach statistical significance (β = 0.26 [95% CI, −0.01–0.52]; p = 0.061), although a numerical trend toward longer procedural duration in the GA group persisted.

In weighted UniFrac analyses, developmental stage and sex did not reach statistical significance (F = 17.33, R2 = 0.257, p = 0.073), but showed a trend toward differentiation.

As an exploratory analysis, we examined the relationship between tumorous CA9 mRNA expression and circulating CA9 levels in 32 HCC specimens and observed a positive trend that did not reach statistical significance when assessed by Spearman’s rank correlation ( online supplemental figure 8 , online supplemental table 15 ).

Similarly, the percentage of peripheral blood blasts showed a trend toward reduction, with a median of 19.5% (7.0–24.0) in TP53 -mutated AML versus 21.0% (16.0–26.0) in non-mutated AML, although the difference did not reach statistical significance ( p = 0.055) (see Supplementary Fig. 1 ).

Pars fractures showed a trend toward association but did not reach statistical significance.

Notably, the proportion of participants with PD showed a decreasing trend across increasing quartiles of total MUFAs intake, although this difference did not reach statistical significance in the matched sample.

The vigor scores also showed an increasing trend, although the change did not reach statistical significance.

In the HCF model, serum total cholesterol and triglyceride levels showed a decreasing trend in the FV-HCF group compared to the MASH-HCF group, however, the differences did not reach statistical significance ( Fig. 2A and 2B ) ( p = 0.0818 for serum total cholesterol level and p = 0.2593 for serum triglyceride level).

Regarding age, using the 50–59 age group as the reference, the 30–39 age group had a significantly higher GHQ-12 score (IRR = 2.18, 95% CI: 1.05–4.56, P = 0.037); the < 30 age group also showed a trend toward higher scores, though it did not reach statistical significance (IRR = 2.15, 95% CI: 0.95–4.85, P = 0.067).

Although IGFBP7 did not reach statistical significance (p > 0.05), its high expression still showed a trend towards poorer prognosis (Fig. 2 A, B).

In early-stage NSCLC population, although a negative trend was observed, it did not reach statistical significance at any percentile.

Analysis according to overall clinical stage showed a trend toward higher EpAb3-5-assessed EpCAM expression in advanced-stage disease (Stage III-IV) compared with early-stage disease (Stage I-II), but this difference did not reach statistical significance (Figure 2 C).

CRP did not reach statistical significance (95% CI, 0.496-0.732; AUC=0.614; P=0.071), although it showed a trend toward predictive relevance.

Starvation led to progressive body weight loss in both groups, and Trim24 −/− mice showed a trend toward more rapid weight reduction over time, although this difference did not reach statistical significance under the conditions tested ( Figure S4B ).

These findings indicate a positive trend favoring the treatment group on expository language outcomes; however, this difference did not reach statistical significance after adjusting for baseline oral narrative language ability. 9.6.

CLDN6 expression showed a trend toward shorter PFS but did not reach statistical significance ( p = 0.096).

In contrast, patients with PE exhibited significantly higher methylation levels in T compared with D tissues ( p = 0.035), while A tissues showed a trend toward higher methylation compared with D tissues, although this difference did not reach statistical significance ( p = 0.052).

Although moderate and severe myopia showed a trend toward greater residual myopia compared with mild myopia, these associations did not reach statistical significance.

The cCMV group also showed a trend toward more specific clonotypes than the aCMV group, but this did not reach statistical significance (P = 0.086).