Within the population with T2DM (N = 180), contrary to our initial hypothesis, metformin treatment showed a numerical trend towards shorter PFS, though this did not reach statistical significance (HR = 1.41, 95% CI [0.97–2.05], p = 0.069).
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While our analysis of axon projections did not include the VMH, we observed a small trend in the predicted direction when we compared BLA innervation between SERT-Cre and ePET-Cre mice, but this did not reach statistical significance.
The H 2 O 2 content showed an increasing trend post-treatment, but the differences compared to the control did not reach statistical significance throughout the treatment period.
A favorable trend was found in AT + RT group but did not reach statistical significance (Fig S2a).
Although changes in methionine levels did not reach statistical significance, they show a definite trend of depletion.
High frailty showed a trend toward delayed adjuvant initiation but did not reach statistical significance after multivariable adjustment (adjusted OR 0.14, 95% CI 0.02–1.35; p = 0.089) (Table 7 ).
AMH expression ( Figure 7C ) showed a trend in diminution although it did not reach statistical significance ( Figure 7A ).
Our findings showed a trend for structural improvement to occur more frequently in the group without AF recurrence, but the difference between groups did not reach statistical significance.
Similarly, patients with liver metastasis showed a trend toward poorer survival, although this did not reach statistical significance (median OS 7.9 months vs 20.2, HR=2.61, 95% CI 0.72 to 9.17, p = 0.056, online supplemental figure S2B ).
A new left bundle branch block (LBBB), the most common conduction disturbance after TAVI, showed a trend toward a lower PPM stimulation rate in our data but did not reach statistical significance.
Only the L/O ratio showed a trend toward higher values in the V-shape group, but this did not reach statistical significance.
CMC2.23 at 20 μM showed a trend for reduced TYR and MITF but the levels did not reach statistical significance ( Figure 3 F).
Although Interleukin‐17 (IL‐17) level showed a decreasing trend, this change did not reach statistical significance (Figure 3C ).
Subgroup analysis of only pure intestinal-type gastric adenocarcinoma, excluding cases with mixed histology (n = 58), showed a trend towards association with OS but did not reach statistical significance (Kaplan Meier, log rank test, P = .069), though there was a significant association with RFS (Kaplan Meier, log rank test, P = .041).
In addition, mice vaccinated with either peptide 2 or peptide 4 VLPs showed a trend toward reduced dermonecrosis (ulcer area) on days 2 and 3 post-infection, although this did not reach statistical significance ( Figure 3C ).
Respondents who infrequently managed hypothyroid patients showed a trend towards affirmative responses, although this difference did not reach statistical significance ( Table 1 ).
Although younger age and lower BMI showed a trend toward better outcomes, they did not reach statistical significance.
However, patients showed higher systemic inflammatory activity, with elevated CRP levels, whereas ESR showed a trend toward an increase that did not reach statistical significance.
Furthermore, patients with elevated chromogranin A (CgA) or high Ki67 showed a trend to poorer OS; however, these differences did not reach statistical significance (log-rank test p = 0.07).
Regarding surgical access, we found a trend toward significance, but it did not reach statistical significance ( P = 0.095).
Although BNP levels showed a decreasing trend in the HIIT group, results did not reach statistical significance.
Muscle weight and physiological cross sectional area (PCSA) showed a trend of reduction in affected dogs although the difference did not reach statistical significance.
The absence of pCR following neoadjuvant chemotherapy showed a trend toward increased progression risk (HR = 2.15, 95% CI: 0.83–5.55), but this did not reach statistical significance ( p = 0.113).
Examination of Foxp3 + cells representative of T regulatory cells, showed an increasing trend in Rip2-deficient mice compared to wild-type mice although it did not reach statistical significance.
Paternal BMI in overweight/obese ASD children also showed an increasing trend, but did not reach statistical significance.