The Effect of Metformin on Atezolizumab/Bevacizumab Treatment in Patients with Hepatocellular Carcinoma and Diabetes.

Oncol Res · 2026 · PMC13040334 · PMID 41930153

Europe PMC DOI

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did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

a numerical trendno p-value reported

Within the population with T2DM (N = 180), contrary to our initial hypothesis, metformin treatment showed a numerical trend towards shorter PFS, though this did not reach statistical significance (HR = 1.41, 95% CI [0.97–2.05], p = 0.069).

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