The close-to-significant effect of FMT at week 1 compared with week 8 indicates that most patients have an initial treatment response and that most CDI recurrences happen after week 1.
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“close-to-significant”
In the literature
Nonetheless, the close-to-significant effect of weather conditions on pseudoword processing hints at a broader influence of environmental factors on cognitive processing.
All other close-to-significant observations are reported in SI Table S6 .
The forest plot illustrated a close-to-significant decreased risk of SPs with increased levels of vitamin D intake (OR = 0.95, 95%CI:0.90–1.02), and statistically significant heterogeneity was found ( I 2 = 54.9%; P = 0.018) ( Figure 2 ).
An intronic variant of POLR1C – a gene that is associated with Treacher Collins Syndrome, sensorineural hearing loss 22 and systolic BP 44 – POLR1C *rs186798404 was the only SNP that had a significant effect in the AFR meta-analysis, though it may be a false positive (there are no significant or close-to-significant high LD SNPs).
Results Resting pre-test postflight variables We identified elevations to resting TPR immediately following spaceflight and prior to LBNP, accompanied by close-to-significant increases in SBP and DBP, and reductions to Q ̇ , with marked reduction in SV (Table 2 ).
Both dye coverage and peak index were significantly correlated with distance to the nearest tree, while in the case of preferential flow fraction and length index the correlations were close-to-significant.
There was a close-to-significant correlation with the Jaccard indexes and a significant correlation with the agreement scores.
Individuals with recurrent acute and chronic pouchitis were characterised as having significantly lower intake of vitamin A, cryptoxanthin and lycopene, and for β-carotene a close-to-significant difference was observed.
Several studies of environmental risk factors in sporadic behavioral variant FTD found a significant association with head trauma and a close-to-significant association with thyroid disease. 7 Furthermore, elevations in cerebrospinal fluid cytokines, notably TNF-α, have previously been demonstrated in FTD. 8 An association between MND and autoimmune diseases also have been suggested previously.
A Cochrane meta-analysis, on the other hand, showed significantly better bacteriologic cure and a close-to-significant advantage in clinical cure in patients treated with teicoplanin as compared to the ones receiving vancomycin treatment [ 74 ].
Adjusting for lifestyle factors, energy intake and macronutrients resulted in a close-to-significant p trend in the youngest group (OR = 1.482, 95% CI = 0.514–4.272; p trend = 0.060) (Model 2).
No clinical, surgical or epidemiological variables were significantly associated with residual TR persistence, although annulus diameter showed a close-to-significant association.
Two studies ( GSE43490 , GSE7621 ) showed a close-to-significant enrichment after the BH correction; in one study ( GSE49036 ), the OPC markers were significantly enriched in the expression signature of OPCs and neurons, while, in the other study ( GSE20292 ), no significant enrichment was found in any cell type for the OPC markers. 2.5.
Because of the significant difference in years of education and the close-to-significant effect on psychomotor speed, we removed the covariance of these measures from the subsequent functional connectivity analyses by means of least squares regression. 3.2.
However, pathway analysis performed on the top close-to-significant genes and lower false discovery rates revealed that the miRNA-219 family (involved in resolution of acute inflammation), the phosphorus oxygen lyase activity pathway, and the CD44 gene were associated with BPD and/or death.
At univariable analysis, age ( p = 0.136), site of origin ( p = 0.663), and positive margins ( p = 0.479) did not influence CFS, whereas female sex (HR = 2.10, 95% CI 0.90–4.80, p = 0.085) ( Figure 3A ), grade of dysplasia (HR = 2.11, 95% CI 0.92–4.84, p = 0.077), and history of previous OSCC (HR = 2.65, 95% CI 1.18–5.96, p = 0.019) ( Figure 3B ) showed a significant or close-to-significant association.
The close-to-significant association seen between HHV-8 and longer LTLs is notable as it stands as the only virus in our multivariable model with an almost-independent association with LTL.
Results for the MacDQoL showed a sizeable AMD-associated reduction in quality of life on average (i.e., mean score of –3.9 where 0 is no impact), with a close-to-significant correlation between worsening acuity and greater AMD-associated reduction.
Only the FNPA-PF scores showed a close-to-significant negative correlation with age , r = -. 308 , p = . 018 > α = . 017 , r 2 = . 09 , suggesting that older participants have lower scores on the FNPA task.
In boxplots corresponding to significant and close-to-significant differential gene expression, we found increased levels of TRIB2 and CENP2 corresponding with obesity (BMI > 30) and lymph node metastasis ( Figure 4 B).
Our analysis revealed a close-to-significant association with anhedonia severity, with an r -value of 0.199 and a p value of 0.086.
In contrast, a close-to-significant correlation was observed between the number of kilometers driven per year and the number of infractions in the more demanding scenario and overall (SDC1: r = −0.178, p = .153; SDC2: r = −0.226, p = .068; Overall: r = −0.221, p = .075).
Clinical TNM stage and RCB grade were identified as independent factors influencing EFS and OS, while treatment group was identified as an independent factor influencing EFS, with a close-to-significant impact on OS.
Other proteins showed close-to-significant associations with the trait of ‘fluid intelligence score’, such as plasma protease C1 inhibitor ( P CSF = 4.19 × 10 −4 , P plasma = 6.97 × 10 −4 ), and with the trait of ‘maximum digits remembered correctly’, such as tenascin ( P plasma = 3.42 × 10 −4 ).