The results suggest that there may be a mediating mechanism, as evidenced by the close-to-significant findings combined with the significant effects of time and PSQI.
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“close-to-significant”
In the literature
In the first step, all variables with significant or close-to-significant associations in bivariate analyses were included in the model.
Trends toward improved survival were observed in 4 additional cancer types, with a close-to-significant p value of 0.072 in esophagogastric cancer ( Figure 5 B).
For adult populations, our meta-analyses showed a close-to-significant favourable effect for mental symptoms, M (SMD) = 0.33, 95% CI [–0.03, 0.69], which was significant when analyses were limited to high-quality studies and larger for clinical compared to non-clinical populations.
A close-to-significant QTL was detected on LG16 for this variable considered whatever the year and the shoot type.
The carcinogenic ratio, which combines E3, 4-OHE (1 and 2), 16α-OHE1 and 2-OHE (1 and 2) provided more interesting results, given the significant or close-to-significant results for the treatment groups and lack thereof in the placebo groups.
None of these factors were significantly associated with the rate of minor surgical complications at multivariate analysis; however, nodal status was close-to-significant ( Table 6 ).
There was also a close-to-significant tendency for a higher frequency of anti-anxiety medication in patients with obesity versus overweight.
This close-to-significant difference was probably due to the higher proportion of alpha blocker treatment, a major risk factor for IFIS, in the study group, as mentioned [ 26 ].
In addition, our TCGA analysis revealed a close-to-significant association between high DSG3 mRNA expression and improved overall survival.
The close-to-significant interaction in the main model, the post-hoc analyses on QSS slope trend estimates, and the visual inspection of Figure 8 show that realistic landmark visualization is most helpful in landmark sequence memory for participants with low spatial abilities, and this difference between the conditions diminishes with increased spatial abilities. 3.3.3.
Anthropometric variables with significant or close-to-significant associations with shoulder glenohumeral osteoarthritis in bivariate analyses (age, scapular length, glenoid width, glenopolar angle, and α angle) were not maintained in the predictive multivariate model for glenohumeral osteoarthritis.
Significant or close-to-significant contrasts were observed between the blocks with largest (peak) lateralization and the blocks with lowest lateralization (middle blocks, highest visibility), for both human and monkey face stimuli ( Table 2 ).
These close-to-significant results may be due to insufficient statistical power; therefore, future studies with larger samples may find common activity patterns in these areas.
After correcting for multiple comparisons using the FDR method, there were two significant and two close-to-significant correlations in the musician group and none in the non-musician group.
Gender Differences in Responses to the Trainer Survey Of the 14 issues tested, 5 had significant or close-to-significant gender differences: In track design and surface, after combining levels 2, 3 and 4, male respondents (M) were more likely than female respondents (F) to say that their horses raced on other types of tracks (gradual turning turf: M = 17, F = 9; gradual or tight turf or synthetic: M = 10, F = 5; other: M = 16, F = 1) (Χ 2 = 6.1, p = 0.048).
This decrease in plasma levels was counterbalanced by a close-to-significant increase of adiponectin and adiponectin receptor protein levels in the hippocampus of Swiss Webster mice fed a HFD.
It was not until recently that statistically significant increases in insulin resistance index and close-to-significant increases in glycated albumin were confirmed in both male and female astronauts aboard the ISS ( Hughson et al., 2016 ).
In addition, TBARS concentrations showed a close-to-significant relationship with increased endometriosis risk [OR 1.6; 95%CI 1.0–2.8], and classification by TBARS concentration tertile revealed that the association between endometriosis risk and concentrations of BPA [OR 2.0; 95%CI 1.0–4.1] and Σbisphenols [OR 2.2; 95%CI 1.0–4.6] was only statistically significant for women in the highest TBARS tertile (>4.23 μM).
Generally, we found significant or close-to-significant associations of Gf with mathematics achievement and reading comprehension after controlling for gender.
Significant or close-to-significant interaction effects were followed up by Bonferroni-corrected post-hoc contrasts to evaluate any differences between the AQ groups.
In principle, however, this group could have adapted their slope through reinforcement learning in partial and no-feedback trials, which might explain the close-to-significant p-value in the vertical dimension.
Additionally, patients with altered p53, Nrf2, SWI/SNF, and TGF-β pathways showed a significant or close-to-significant association with higher TMB ( Supplementary Figures S4C, D ).
These studies indicated that 24 h following incubation with the glycolysis inhibitor, p65 activation by TNFα + IL-1β was reduced in both TNBC cells ( Figure 9 B); here again, downregulation of p65 by the glycolysis inhibitor (2-DG) in MDA-MB-231 cells was consistent in three different independent experiments ( p = 0.0505; Table S7B ); however, they came out only close-to-significant when considered all together ( Figure 9 B2) because of variability that was noted between the different experiments in the levels of phosphorylation in cells without inhibitors, and in the extent of decrease in p65 induced by 2-DG ( Table S7B ).
The mean MMSE scores and the percentage of physical restraints in the three groups showed close-to-significant differences (table 3 ).