In addition to ART-associated factors, our study revealed additional established factors associated with changes in the CD4/CD8 ratio, including a lower recovery in association with older age, and higher recovery with higher CD4/CD8 baseline ratio and, close to significance, with longer regimen duration. 8 , 9 Those findings support the consistency of our results.
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In the literature
We determined that the data met assumptions for sphericity using Mauchly’s test, though this value was close to significance in some cases.
Furthermore, although there was no statistically significant difference in the association between Ht-TKV and %Ht-TKV annual changes in this study, the P value was 0.054, which is close to significance considering the rather small sample size.
Thus, because the upper band is statistically more abundant in the cancer patients than in the healthy ones and the difference in the lower band ODs is close to significance, we conclude that the increased ERG1 protein abundance in the muscle of cancer patients is important.
These increases in temperature were therefore close to significance in summer and early autumn. 3.1.
Despite this, a numeric difference was observed, and the p -values were close to significance, suggesting that a larger sample population and fewer variables would potentially allow the difference to reach significance.
Accordingly, inspection of Table 1 shows that four correlation coefficients were close to significance.
While only half of the participants reached significance in individual analyses for the posterior strain gauge, as shown in Table 1 , many are close to significance.
Amongst the variables included in our model, the presence of extrapulmonary metastases significantly worsened progression risk (HR 2.67, 95% CI 1.54–4.64, p = 0.001), while its influence on mortality (HR 1.98, 95% CI 0.99–3.98, p = 0.054) was close to significance.
When Cox regression analyses were performed according to anti-apoA-1 IgG seropositivity , the aforementioned associations remained unchanged, at the exception of all-cause mortality which remained significant after adjusting for renal function, and for which the association became close to significance after adjusting for previous MI on top of age and gender ( Supplementary Table S2 ).
Ancylostoma infection was close to significance for being moderately underweight, but not for being severely underweight.
However, some tendencies were demonstrated, especially in the case of post-stroke seizures, which were present in 67% of girls and in 18% of boys in the group of infants and toddlers, but the difference was close to significance.
Two other features (A10 and A11) were close to significance with P values near 0.05.
AST levels are highest in the VaAc group, with a p-value close to significance (0.061), while ALP and γ-GT activities show no significant changes across treatments ( p = 0.201 and 0.148, respectively), (Table 9 ).
The incidence of streptococcal infections showed a clear trend (close to significance by joinpoint regression) to an increase.
Calculating only female samples, the correlation coefficient is -0.493 for the basal and − 0.451 for the stimulated release values (both close to significance).
Testing was carried out in additional participants when associations were significant or close to significance.
To determine the variables affecting depression, anxiety, and stress levels of participants, variables that were statistically significant and close to significance in the previous analyzes were tested with Binary Logistic Regression analysis in multivariate analysis.
In the case of intake of meat ( p = 0.061) and intake of meat per 1000 kcal ( p = 0.083), the differences were close to significance.
By applying the formula given above to all of the halved p -values of the regressions shown and then comparing the test statistic to a chi-squared distribution with 12 degrees of freedom (−2 Σ k i = 1 ln(p i ) = 20.994), the resulting pooled p -value is 0.050458, which is close to significance.
A meta-analysis conducted on both datasets revealed that childhood unpredictability and childhood adversity were significantly related to participants' susceptibility to follow other people's opinion, while the average effect of childhood harshness was close to significance.
GPx activity represented a positive correlation with weight, BMI, and WC in patient group and close to significance correlation with HDL-C and TC levels in all participants.
For the functional well-being assessment, all time points were significantly different between treatments ( P < 0.038), except for one time point (at cycle 2, day 28, P = 0.061) which was close to significance.
While other risk factors were investigated in relation to development of DIC, such as age, previous splenectomy, and association with Lyme disease, none were close to significance [ 20 ].
While for most subgroup analyses, the P -value for GA vs GG genotypes was significant or remained close to significance level and I 2 showed moderate heterogeneity among studies, P for heterogeneity was not significant for AA vs GG genotypes ( Table 2 ).