Multivariate analysis revealed that heart disease (HR 1.94, 95% CI 1.070–6.793, P = 0.035), T-stage (HR 1.94, 95% CI 1.340–2.840, P < 0.001), and N-stage (HR 1.73, 95% CI 1.102–2.739, P = 0.017) were independent prognostic factors for DFS, with age approaching significance ( P = 0.061).
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cfDNA+ patients more frequently had a higher ECOG performance status (LL3: P =0.0029; LL6: P =0.0022), greater tumour burden (measured as the sum of the longest diameter of target lesions; approaching significance in LL3: P =0.061; LL6: P =0.0001), more metastatic sites (LL3: P =0.0003; LL6: P <0.0001), and metastases to the bone (LL3 and LL6: P <0.0001) and liver (LL3: P <0.0001; LL6: P =0.0003; Table 2 ).
There were no significant group differences in demographic variables, although the difference between the three groups in racial composition was approaching significance (Monte Carlo two-sided significance test, p = .061, 99% CI [.055, .067]).
HCWs were not different between the treatments, with the difference between the normal (NBW-HF) pigs and the low (LBW-HFHD) birth weight pigs approaching significance (p=0.0615).
The standard dose boosted group remained superior in enhancing IgG responses compared to the half dose group (median = 2622 and 1952 BAU/mL, respectively), but the difference was approaching significance ( p = 0.0616) ( Figure 4 A).
However, trends approaching significance were observed in comparisons involving Triple-Negative vs HER2-enriched ( P = 0.062) and Luminal B subtypes ( P = 0.057).
Daily liquid intake was the only measure approaching significance ( p = 0.062), with 48.7% of the probiotic group drinking only 1–4 cups per day compared to 27.6% in the control group.
A repeated measures ANOVA with a Greenhouse–Geisser correction ( ε = 0.617) revealed a main effect of View Content approaching significance, F (1.851, 62.922) = 2.970, p = 0.062, partial η 2 = 0.080.
The direct effect of T1 mathematical skills on T3 MA was approaching significance ( p = 0.062).
Plasma Testosterone A one-way ANOVA conducted on plasma testosterone levels across exposure groups revealed no significant difference in levels at α = .05; however, P values were approaching significance (F (2,26) = 3.102, P = 0.062).
Paired t -tests indicated significant effects for the Mindfulness ( t (1, 11) = −2.688, P = 0.028) and Iyengar ( t (1, 8) = −2.688, P = 0.028) groups and an effect approaching significance in the BWV group ( t (1, 11) = −2.082, P = 0.062).
This was also reflected in a main effect of Strain approaching significance ( p = 0.062); however, there was no effect of Treatment Time ( p = 0.097) and its interaction with Strain ( p = 0.298) on GFAP gene expression.
Fast food consumption was also associated with BMI, with less than once a month (B = 2.81, 95% CI: 0.21, 5.43, p = 0.034), once a week (B = 3.47, 95% CI: 0.82, 6.12, p = 0.034), twice a week (B = 3.2, 95% CI: 0.27, 6.14, p = 0.032), four times a week (B = 6.45, 95% CI: 2.16, 10.74, p = 0.003) all illustrating a significant relationship, with more than seven times a week approaching significance (B = 11.11, 95% CI: -0.56, 22.78, p = 0.062).
The difference in BLa between PACER and FBL was also approaching significance (MD = 1.1 mmol·L −1 ; CI = −0.04, 2.19; P = 0.062, d = 0.83; Table 2 ).
Among the blood parameters, while the difference in total cholesterol did not reach statistical significance (p=0.062, approaching significance), the lipid profile demonstrated notable differences between the OSA group and the non-OSA group.
Positive Affect (PANAS) Results from the positive affect scale of PANAS showed a main effect of age approaching significance, F (1,198) = 3.51, p = 0.062, η p 2 = 0.02 (BF = 0.76) with young adults having higher scores than older adults.
2.2% in male patients, p=0.021), and the BRAF mutation was higher (approaching significance) in right-sided CRC than left-sided CRC (10.5% vs. 3.4%, p=0.062).
In 77 individuals with FTLD spectrum diagnoses (29 MCI, 48 dementia), only TabCAT‐BHA (β = −1.341, P = 0.002) was significantly associated with the baseline CDR+NACC/FTLD, with plasma Aβ42/40 ratio approaching significance (β = −116.093, P = 0.062).
17; centro-parietal approaching significance: F (1, 28) = 3.79, p = . 062].
3b ). The supernatant assays further revealed a significant donor effect (ANOVA: F 47,76 = 3.90, p < 0.0001) and a receiver effect approaching significance (ANOVA: F 43,80 = 1.49, p = 0.062).
Plasma serotonin levels were higher in the OLIV group, approaching significance ( P = 0.0622).
The linear coefficient of 0.61155 (p < 0.001) signifies a strong linear effect, while the quadratic coefficient of −0.10510 suggests a marginal quadratic effect that is approaching significance (p = 0.0623).
A Wilcoxon matched pairs test showed a p-value that was approaching significance (p = 0.0625).
Although no pairwise comparison yielded statistical significance at the conventional α = 0.05 level, values approaching significance (e.g., p = 0.0625) were observed, particularly between HydroPredictor and SVM.
Because polyamine biosynthesis is altered in human ESCC ( 35 ), the result that the level of putrescine was reduced by 48% with a P value approaching significance ( P = 0.0625) ( SI Appendix , Fig.