“an unfavorable trend”

In contrast, an unfavorable trend in the incidence of coronary heart disease in young adults in the USA has been explained by considerable increases in abdominal obesity, diabetes, and hypertension ( Ford and Capewell 2007 ).

In fact, while mortality rates from other types of cancer are decreasing, pancreatic cancer is the only malignancy with an unfavorable trend[ 2 ].

In addition to instrumental methods for the diagnosis of cardiac fibrosis and diastolic dysfunction, an unfavorable trend in serum PIIINP levels was found.

In addition, there was an unfavorable trend in the period effect of hypertensive heart disease due to cold temperatures in North America.

Regarding βB application, an unfavorable trend was observed in the more severe KD subgroups (Figure 2 ).

22 In IFNα, although e13a2 transcript was associated with an unfavorable trend in outcomes and treatment responses, no data were sufficient to define the type of transcript as an independent prognostic factor.

When comparing compounds 3 , 4 and 5 , that carry 2, 3 or 4 methylene groups respectively, a steady increase in binding enthalpy is observed which was counterbalanced by an unfavorable trend in entropy.

In Italy, the proportion of women among all Doctoral graduates fell by over three percentage points between 2013 and 2024, an unfavorable trend that raises concern.

The impact of LDHA expression level was not statistically significant ( p = 0.16), but an unfavorable trend can be observed. 3.2.

When stratified by line of therapy, antibiotic use also showed an unfavorable trend among patients receiving first-line therapy, mixed line therapy under the random-effects model.

Conclusions To sum up, the results of our study indicate a growing trend for the use of testosterone and anabolic–androgenic steroids and an increasing trend for gaining knowledge about these substances and their possible side effects, which unfortunately goes hand in hand with an unfavorable trend towards self-diagnosis and self-treatment of these effects.

Conclusion Our study identified an unfavorable trend in the use of telehealth among Hispanic patients.

An unfavorable trend occurred in three patients before the end of the first trimester of life due to multi-organ failure.

SRD patients might display specificities regarding their healthcare requirements, as well as their short- and long-term prognosis: the intensivists concerns are to determine which characteristics are associated with ICU-mortality, and the internists need to identify which categories of patients will undergo an unfavorable trend after ICU discharge, in terms of long-term mortality, morbidity, and SRD evolution.

In China, shifts in lifestyle and economic development have contributed to an unfavorable trend in obesity rates.

CONCLUSION In recent years, there has been an unfavorable trend in the epidemiological indicators of CRC in various countries around the world.

Unfortunately, we observed an unfavorable trend in etiologies for alcohol consumption and NASH, which indicated that more targeted and specific strategies should be established to limit alcohol consumption and promote healthy lifestyles in high-risk countries, especially in middle-high SDI regions and Eastern Europe.

Other important findings include the overall increase in EC2 rates among Whites and Blacks over time and serous carcinoma among all groups ( Supplementary Table 1 ), which can only be described as an unfavorable trend.

Even more concerning are the data from recent years, reflecting an unfavorable trend in the country.

These research results show an unfavorable trend taking place, not only in the military environment [ 29 ].

The net cohort effect in the United States showed an unfavorable trend, mainly due to rising smoking rates and the emergence of an economic crisis.

However, in recent years, an unfavorable trend has been outlined, with hepatitis A continuing to occur in hyperendemic regions and emerging in areas of low endemicity [ 7 ].

The incidence of PCa in China is steadily increasing, and over the past 30 years, the disease burden caused by PCa has further escalated, indicating an unfavorable trend ( 2 ).

However, an unfavorable trend emerged in cohort groups born after 1968, which became more evident in female populations.

Additionally, within donors aged ≥65 y, the absence of an association (or even an unfavorable trend) between exact donor age and survival, or between donor age ≥70 versus 65-69 and survival, is reassuring, as it indicates that at least up to the maximum donor age of 76 in this study, there are no insurmountable survival disadvantages attributable to increased donor age that cannot be largely mitigated by careful donor selection.