“an unfavorable trend”

However, an unfavorable trend emerged in cohort groups born after 1968, which became more evident in female populations.

In China, shifts in lifestyle and economic development have contributed to an unfavorable trend in obesity rates.

These consistent results demonstrate that an unfavorable trend of change in bone health in T2DM patients may be occurring in the United States.

In Italy, the proportion of women among all Doctoral graduates fell by over three percentage points between 2013 and 2024, an unfavorable trend that raises concern.

These research results show an unfavorable trend taking place, not only in the military environment [ 29 ].

In addition, there was an unfavorable trend in the period effect of hypertensive heart disease due to cold temperatures in North America.

However, the period effect for males shows an unfavorable trend over the period 2005-2014.

4.7% placebo) also suggested an unfavorable trend toward harm, although the difference was not statistically significant.

In contrast, an unfavorable trend in the incidence of coronary heart disease in young adults in the USA has been explained by considerable increases in abdominal obesity, diabetes, and hypertension ( Ford and Capewell 2007 ).

47 , 48 However, this study also found an unfavorable trend in the mortality of liver disease due to hepatitis B in women of childbearing age in Australasia, Eastern Europe, and High-income North America between 1990 and 2021.

It is worth noting that despite increasing fatigue life, the addition of the TOAS-derived bitumen shows an unfavorable trend with respect to applied strain.

Another study revealed an unfavorable trend towards a westernized diet in West Asia and in North Africa ( 48 ).

The reduced Young’s Modulus may indicate a ,,pseudo-plastic effect” for ceramic-polymer cements, while the compressive strength after modification showed an unfavorable trend.

There was a favorable trend of clinical improvement and mortality in patients on mechanical ventilation, but also an unfavorable trend in non-mechanically ventilated subjects ( Sanofi, 2020 ).

The pathogens were less susceptible to penicillins (55.8% and 49%) in both groups. Discussion Our results should be considered as an unfavorable trend towards an increase in the prevalence of resistant isolates.

A stratified Cox model yielded a HR of 1.60 (95% CI: 0.78, 3.27) in Arm A and 1.53 (95% CI: 0.75, 3.15) in Arm B compared to SOC, indicating an unfavorable trend for the abemaciclib arms. 3.4 Safety Treatment‐emergent adverse events (TEAEs) occurred in >99% of the treated patients ( n = 98).

Suicide mortality rates were decreasing significantly in all age groups in both sexes from 1991 to 2020: The only exception was for males in age group 40-49, with an unfavorable trend of suicide mortality by hanging in 1991-2011 period, with APC = +0.3% per year (95%CI: -0.9 to +1.4).

The incidence of PCa in China is steadily increasing, and over the past 30 years, the disease burden caused by PCa has further escalated, indicating an unfavorable trend ( 2 ).

However, most of these cryptic BGCs are not expressed under conventional culture conditions, which result in an unfavorable trend that the number of novel natural products from the genus Fusarium has been decreasing in the past decade.

Notably, both Complex 1 and Complex 6 exhibit favorable outcomes in terms of Coulombic interactions, whereas Complex 3 demonstrates an unfavorable trend in this regard.

There was an unfavorable trend regarding the 90-day outcomes for the over-80 patients treated for atrial fibrillation compared to patients of the same age group without atrial fibrillation.

Overall, these findings suggest an unfavorable trend in neurological outcomes and disability severity during follow-up among female patients.

Four out of eleven components showed an unfavorable trend for patients with BD compared to healthy controls: Fruit, meat, poultry, olive oil use were all leaning toward the lower scores for the BD patients.

When stratified by line of therapy, antibiotic use also showed an unfavorable trend among patients receiving first-line therapy, mixed line therapy under the random-effects model.

In most countries, there is an unfavorable trend towards their growth; therefore, technological approaches that reduce the harmful effects of fungal diseases are under investigation [ 5 , 6 , 7 ].