“an overall trend”

There was an overall trend toward a higher percentage of patients reaching the primary end points in the CEST group, but the differences did not reach statistical significance.

The relaxation rates show an overall trend consistent with the considerably disordered conformation of PNT. 1 H– 15 N NOE values are all well below 0.5, indicating high flexibility of the backbone (Supplementary Figure S1 A).

Although partial overlap was observed between the HF and LF groups, an overall trend toward separation was noted, both in the positive and negative ion modes ( Figures 3A , B ).

The slightly greater dose density of both chemotherapeutic agents in the cisplatin + fluorouracil regimen in women with respect to men does not appear sufficient to account for an overall trend toward greater response benefit of chemotherapy in men that, as we will see later and as previously reported, does not translate into a survival benefit. 42 This lower ORR in females may have to do with a higher percentage of diffuse cancers that are less chemosensitive.

When looking specifically at risk preferences, a recent meta-analysis reveals a strong variability in the effects described in the literature, all converging toward an overall trend of slightly enhanced risk-seeking for others relative to one’s self ( Polman and Wu, 2020 ). 1.2.

Although not statistically significant, visually there does appear to be an overall trend in benefit of anticoagulation.

In the past 20 years, energy consumption for human activity and economic development in the YRB has been relatively large, showing an overall trend of fluctuating growth. 3.1.2.

Using a more stringent coding system, however, despite an overall trend for agreement, high levels of inconsistency were nevertheless detected, particularly in the readiness dimension (58% for adults and 66% for families).

Spearman’s correlation coefficient was used to determine tonicity of the calibration curves to find an overall trend within the data [ 23 ].

On both datasets, the model accuracy exhibits an overall trend of rising significantly first and then stabilizing as D increases, indicating that D plays a crucial role in determining the temporal feature extraction capability of EEG signals.

The results found that the total discharge and manure N and P loads in animal manure nutrient showed an overall trend of increasing first and then decreasing in the Yangtze River Delta in the soil from 1980 to 2018.

Further, constructs with increasing number of NPXY motifs (0–12) showed an overall trend of enhancing binding affinity in the PTB-less isoforms, although this trend is not linear, suggesting there is some specificity to the binding possibly associated with structure conformation (Fig. 5C ).

We are reporting global changes, which showed both up and downregulated genes, with an overall trend of more genes showing downregulation than upregulation (2897 total downregulated genes versus 1264 upregulated) even after removal of confounding Y-linked genes reported as downregulated in female cell lines ( Figs 2B and S4A , Supplemental Table 3 ).

Notably, lifestyle OBS was significantly negatively associated with female infertility risk in an overall trend both before and after the inflection point when lifestyle OBS was in the range of 2 [OR (95% CI) = 1.076 (1.036, 1.119)] to 5 [OR (95% CI) = 0.958 (0.935, 0.982)].

In any case, there is an overall trend towards better outcomes in cohort B.

As an overall trend, we can see that the competition outcome depends on the initial mixing ratio of the two species ( Fig. 1D ).

Across all measures, achievement was associated with an overall trend toward increased service utilization and health care costs for RA patients, but the increased service use was not evenly distributed across sites of care.

T-SCM cells demonstrated an overall trend of higher cell proliferation at 72 h across all donors than T-TM and T-EM ( Figure 3B ).

An overall trend is observed here – low top-L contact orders (top-L CO<20) tends to favour all contacts approach, while high top-L contact order (top-L CO>25) favours sequential contacts rather than all contacts approach.

4 ) show an overall trend of increase in accuracy in all species as the sample size is increased.

However, children aged 2 or 3 years (solid blue line) had a smaller decrease in volume, although there was still an overall trend for shrinkage.

Consistent observations have been described in clinical registries and pharmacovigilance analyses of combined antithrombotic therapy, indicating an overall trend toward increased bleeding and cytopenic risks relative to single agent use [ 57 ].

2 , with an overall trend of increasing age in less deprived deciles.

Freeze–thaw cycles reduce and then stabilize soil shear strength With the increase in the number of freeze–thaw cycles, the shear strength of the three soils showed an overall trend of decreasing and then stabilizing, which is consistent with the previous study 11 .

db/db mice with PAX6 replenishment displayed a long‐term improvement in hyperglycemia and elevated serum insulin level with an overall trend up to 5 months compared to db/db mice receiving AAV‐Ctrl (Fig 4A and B ).