“an overall trend”

Our results may suggest an overall trend towards decreasing stigma towards mental illness in today's doctors. 4.4.

In the postoperative ≥12-week period, there was a subsequent decline from the initial improvement; however, an overall trend of improvement compared to baseline was observed.

The content of tightly bound water A 21 increased when moderate amounts of FI were added, showing an overall trend of first decreasing and then increasing.

Therapeutic strategies that target only cardiac mechanisms have had limited success to date, but there is an overall trend in more positive trials of HFpEF interventions to augment EI in the last 5 years.

The exchange of A to C revealed an overall trend towards high mutation frequency, reaching 1.44–1.65 kb −1 under 9 conditions.

The average annual PM2.5 concentration in the Yellow River Basin exhibited an overall trend of first increasing and then decreasing, with a rise from 31.80 μg/m 3 in 1998 to 32.47 μg/m 3 in 2019, marking a 0.67 μg/m 3 increase over the study period.

We calculated a two-tailed P value to assess whether there is an overall trend in the direction of rank correlation between 5′-mRNA folding energy and coding sequence length.

This showed that the increase is part of an overall trend and can in reality not be linked to the FD intervention, in spite of the fact that the health staff perceived it that way [unpublished findings].

Duration of follow-up The risk of developing type 2 diabetes showed an overall trend to increase with the duration of follow-up ( Fig. 3 ).

We anticipate few of these would have a directional effect on our estimates, with the notable exception of an overall trend towards greater sampling intensity.

For adults, age was non-significant, and neither sex nor socioeconomic status were associated with anaemia, with no evidence of an overall trend in odds with decreasing socioeconomic quintile.

We produced an overall trend test for the significance of mental well-being groups by including the groups as a continuous variable (from 1 to 4).

This indicates that while the pooled effect supports an overall trend of poor sleep in KHOA patients, caution is warranted in generalizing the exact magnitude of the effect.

As an overall trend in the TCA cycle, the gene transcription levels in the WP-containing medium were higher than those in other media.

These changes may be attributable to changes in variance with aging (Slieker et al., 2016 ), but they describe an overall trend to increasing variance that would not necessarily lead to a parabolic distribution.

Zonation in plasma B cells is similarly described between small and large intestines in humans, with previous studies describing a dominance of IgA1 isotype in small intestine versus IgA2 in the large intestine and an overall trend toward greater abundance of dimeric IgA plasma cells in the latter 111 .

There was an overall trend from less mature (undifferentiated) cells on day 0 to more mature (differentiated) micromass cultures on day 10 and towards mature articular chondrocytes, indicating a progressively different transcriptome during chondrogenesis.

6 43 To evaluate an overall trend, we added day 5 measurements as well.

demonstrated an overall trend toward improvement, with moderate improvement in subjective pain in 8 of the 10 patients who visited the rheumatology clinic following DAA therapy.

However, globally our expanded analysis includes additional members of the above immune pathways, demonstrating an overall trend toward up-regulation of pro-inflammatory cytokines.

Nevertheless, we find an overall trend that the Cα-H and N—H bond lengths are closer inter-nuclei distances ( Gruene et al., 2014 , Williams et al., 2018 ).

Thus, tortuous microvessel formation increased initially as part of an overall trend, but then decreased while overall microvessel length stabilized, suggesting that tortuous microvessels resolve into normal capillaries over time.

As an overall trend, the transcriptional response of neutrophils peaked after 60 min, independent of the Candida morphotype used for the infection (Fig. 1a and b , Additional file 3 : Figure S2A, Additional file 4 : TableST2).

Tracking the average quaternization per round in Figure 2 B, we observe an overall trend toward the target maximum (20%).

In addition, lifestyle OBS was significantly negatively associated with CircS risk in an overall trend both before and after the inflection point.