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Heart failure and preserved ejection fraction: pathophysiology, clinical assessment, and management of exercise intolerance.

Eur Heart J · 2026 · PMC13286652 · PMID 41984824

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an overall trendno p-value reported
Therapeutic strategies that target only cardiac mechanisms have had limited success to date, but there is an overall trend in more positive trials of HFpEF interventions to augment EI in the last 5 years.

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