Barely Significant
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“a trend towards significance”

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In the literature

With regard to OS, a trend towards significance in favor of patients with an PMA ≥ 0.36 and ACM=0 (median OS not reached; 1-year OS 86.0%, 2-year OS 68.6%) in comparison with patients with an EGFR PMA < 0.36 and ACM ≥ 1 (median OS 4.0 months, 95% CI 1-18; 1-year OS 50.5%, 2-year OS 25.0%) was found (p0.06), with a HR of 4.01 (95% CI 0.78-20.59, p=0.10) (Figure 3 , Panel D).
At multivariate analysis among PD-NC a systolic blood pressure (SBP) > 140 mmHg was the stronger predictor of MCI (adjHR 4.04; 95% CI 1.41–11.3) while the presence of MCI at baseline (adj HR 7.55; 95% CI 1.76–32.3) and a severe WMLs burden (adj HR 2.80; 95% CI 0.86–9.04) were the strongest predictors of PDD, even if this latter association has a trend towards significance.