Barely Significant
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“a trend toward significance”

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In the literature

a trend toward significancep = 0.051.0× alpha
In the unadjusted model, higher MDS-OAβ levels were significantly associated with a lower TBR in the frontal (β = −0.04, p = 0.02), central (β = −0.06, p = 0.02), and temporal lobes (β = −0.06, p = 0.01), with a trend toward significance in the parietal lobe (β = −0.05, p = 0.05).
However, findings from the Italian OBSERVANT Registry indicate that permanent atrioventricular block is less common in female than male TAVI patients (9.6% vs 17.2%), with a trend toward significance for female sex as a protective factor (p=0.05; OR: 0.61). 38 The results are even stronger in studies where CoreValve use predominates, such as the meta-analysis by Zhao et al . 31 One proposed explanation for the higher PPI incidence in men is the use of larger prostheses, as men generally have larger valve annuli.