It is worth mentioning that the majority of (poly)phenols displayed a suggestive trend towards inverse associations with BW gain.
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There was also a suggestive trend of inverse association between a higher maximum BMI in a female’s adulthood and OS.
Contrary to the predictions of the problem individuals hypothesis, we did not find a reduction, but instead a suggestive trend of an increase, in conflict kills following periods with high conflict removal of bears.
Analyses for HbA1c and HOMA-IR are only shown for cancers that we found a statistically significant association with diabetes or a suggestive trend for a cancer previously associated with diabetes such as colorectal cancer.
When these findings are considered alongside results from the multi-ethnic STAR*D cohort, also including participants with MDD, in which no significant associations were observed in Caucasian or African American participants, but a suggestive trend was present in Latinos ( 37 ), the overall pattern is consistent with a population-specific modulation of antidepressant response rather than a universal pharmacogenetic effect.
There was a suggestive trend toward benefit in the primary (Skindex-16) and secondary outcome measures (PHQ-4 and PETS) when looking at the mean differences.
Although no significant association was found between this SNP and the overall risk of AIT, a suggestive trend was observed between rs1126797 genotypes and thyroid volume in affected individuals.
Conversely, in the context of longer-distance ultra-marathon races, where the demands on aerobic and psychological endurance are heightened, there is a suggestive trend that athletes aged 45 years or over might exhibit enhanced performance.
Investigating smoking cessation behaviors, there was a suggestive trend for association between age acceleration and recent smoke cessation only within females compared to males in the multivariate model.
Although any report of night shift work was not associated with atopy risk (OR ever nightshifts = 1.13; 95% CI = 0.97–1.31), we observed a suggestive trend of increased risk of atopy in offspring associated with longer duration of maternal night shift work (OR ≥6yrs night work = 1.27; 95% CI = 0.99–1.63; P trend = 0.07).
This study documents the high detection rate of G2P[4] strain in Brazil after RV vaccine introduction, as widely presented in previous studies 8 , 32 ; however, also reveals a suggestive trend to be replaced by new RV strains (i.e.
For alcohol exposure, none of the main effects found for groups matched for SES met significance, although a suggestive trend for cerebellum volume remained.
Specifically, among African Americans, there was a suggestive trend where ω-3 supplementation seemed to lower the risk of adenomas, hinting at a connection between ω-3 fatty acids and immune system adjustments.
In contrast, specificity was high, reaching 95.8% (95% CI 78.9%‒99.9%) in the total sample, and 100.0% in both the Gilbert and control groups, a suggestive trend that the CNN may be effective in correctly classifying non-dense breasts, though the preliminary nature of these results still necessitates further validation with larger cohorts.
2 E), the positive associations did not reach statistical significance but showed a suggestive trend.
Here, we uncovered a striking signature of selection at β A 21 in Ancash, and a suggestive trend in Lima.
However, there is a suggestive trend of higher cell-associated HIV-1 RNA values in patients of cluster 3 ( Figures 3C, D ).
There was a suggestive trend of lower chances of conceiving with greater adherence to the pooled FPS dietary pattern in Singapore.
On the other hand, there was a suggestive trend indicating that patients with high methylation levels of NKX6-1 might have an increased risk of developing MGL compared to those with lower methylation levels ( p = 0.062, Fig. 3 B), corresponding to a 1.7-fold increase in risk (HR = 1.73, 95% CI 0.80–3.75, p = 0.162, Table 2 ), which reached statistical significance considering the optimal cutoff value ( p = 0.021, Fig. 3 C, aHR = 2.01, 95% CI 0.93–4.33, p = 0.074, Table 2 ).
Treatment increased hemoglobin levels, with a suggestive trend toward greater effect among those with inflammation, supporting the potential utility of HIF-PHIs in complex anemia management.
Some other prospective cohort study showed a suggestive trend of reduced glaucoma risk with higher intake of folate (vitamin B-9) i.e., compared with the lowest quintile of cumulatively averaged total folate intake, the MVRR of exfoliation glaucoma or glaucoma suspect for the highest quintile (Q5; ≥ 654 μg/day) was 0.75 (95% Confidence Interval [CI]: 0.54–1.04; p for linear trend = 0.02) ( 17 ).
Meta-analyses have found that cemented stems are associated with significantly fewer intra- and postoperative periprosthetic fractures compared to cementless options. 3 Registry data support a 59% relative risk reduction with cemented stems. 4 In our study, we observed a clear inverse trend between preoperative YAM and intraoperative fracture risk, especially in underweight patients (BMI < 18.5 kg/m 2 ), with a suggestive trend despite not reaching statistical significance.
In our multivariable model, we observed a suggestive trend with higher risks among survivors receiving etoposide within the HSCT with TBI group.
However, such a difference was not observed, not even a suggestive trend (Supplementary Figure 4 ).
In those who did, there was a suggestive trend for median OS to be longer in patients expressing higher levels of PD-L1; however, there was a borderline statistically significant difference in PFS curves according to the duration of index nivolumab treatment (p = 0.046).