In sum, published studies do not provide convincing evidence of an association between serum PFOA and increased IHD mortality, aside from a suggestive trend among the most highly exposed workers with a 10-year lag.
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“a suggestive trend”
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p=0.06
In the literature
At 18 month (n=197), the offspring born to obese mothers had lost five points in language composite scores and the previous differences in language and cognition was replaced by a suggestive trend of lower gross motor scores in the overweight, obese, and diabetic groups.
In between-intervention comparisons, nivolumab had HRs of 1.44 (95% CrI: 1.00-2.06) versus bevacizumab and 1.31 (95% CrI: 1.06–1.63) versus rindopepimut, indicating a suggestive trend of relatively poorer survival (Figure S3).
Additionally, a suggestive trend toward improvement in MMSE scores was observed in a subgroup analysis of 1,717 participants (pooled standardized mean difference = 0.76, 95% CI: 0.06 to 1.46, t 18 = 2.27, p = 0.04).
The BMI ≥28 × TG ≥1.7 mmol/L interaction term did not reach statistical significance but also showed a suggestive trend (HR = 0.644, 95% CI: 0.381–1.089, P for interaction = 0.105).
However, a suggestive trend was observed in the atlas-based approach (see Supplementary text 4 and Supplementary Fig. 6 ), which shows a sensitivity ratio for V6 of about 20% that is consistent across the 3 animals.
In a study carried out in neonates with NAS, the addition of auricular acupressure beads did not result in a different clinical course, though there was a suggestive trend towards less pharmacological support needed in the acupressure group [ 42 ].
affinis from 27 populations spanning nine degrees of latitude in North America showed a suggestive trend contradicting Bergmann’s rule.
Yet, the results show a clinically significant correlation between LBW and EPB, and a suggestive trend toward increase preterm delivery, highlighting the necessity of perinatal planning and focused surveillance in this high-risk population.
After adjustment for age and sex, higher proportions of EA were estimated for the HICs (New Zealand and the UK) compared with the middle-income country (Brazil) and the low-income countries (Uganda and Ecuador), with a suggestive trend.
However, there was a suggestive trend towards reduced ischemic stroke incidence among females post-HP eradication, though this did not reach statistical significance.
Discussion In the NHANES cohort spanning 1999–2006 with follow-up through late 2019, we observed a suggestive trend toward an association between endometriosis and all-cause mortality.
In both the continuous and categorical eGDR subgroup analyses, although the interaction with diabetes status was not statistically significant, we observed a suggestive trend indicating that eGDR may have a stronger predictive effect on WMH volume in non-diabetic individuals than in those with diabetes. 3.4 Sensitivity analyses Multiple sensitivity analyses consistently supported the robustness of our findings.
Therefore, we conclude that although there was a suggestive trend towards an association, neither rs6885224 in 5p15.2 nor rs634990 in 15q14 showed significant differences in allele and genotype frequencies between the high myopia and control groups.
Nonetheless, a suggestive trend toward more rapid and pronounced ulcer healing was observed in the gentamicin-sponge during the second half of the study (from 3 to 5 weeks) [ 26 ]. 2.2.
We find no evidence of increased autosomal SV burden for probands when compared to unaffected siblings yet observe a suggestive trend toward an increased SV burden on the X chromosome among affected females.
In a study of neonates with Neonatal Abstinence Syndrome (NAS), the addition of auricular acupressure beads did not result in a different clinical course, though there was a suggestive trend toward less pharmacological support in the acupressure group [ 71 ]. 4.1.12.
Therefor, in the intergroup comparisons of changes in upper airway indicators, the digital device is superior to traditional treatment in improving the minimum cross-sectional area of the upper airway, with a suggestive trend toward better outcomes in total airway volume and oropharyngeal volume.
For both stages, P -values between the Bonferroni threshold and 0.05 were considered as a suggestive trend.
We acknowledge that this does not reach conventional statistical significance (α = 0.05) and should be interpreted as a suggestive trend requiring confirmation.
Additionally, a suggestive trend for association with reduced testicular volume was observed among young men, and with lower serum FSH among infertility patients.
The positive association below DI-GM = 3 (adjusted OR = 1.455, p = 0.064) should be interpreted as a suggestive trend rather than a statistically confirmed risk elevation, potentially reflecting limited statistical power or residual confounding; prospective studies are required for confirmation.
In adjusted models, a suggestive trend across tertiles was observed for IL‐1β (trend p ‐value 0.01).
When looking at continuous differences in HDI, we observed a suggestive trend in the effect especially for congenital abnormalities, preterm birth and SGA ( Supplementary Figure S4 ).
This was despite a suggestive trend of a reduction in the number of fish shedding for mixed infections compared to single infections in experiment 2 ( Fig 2B ).