For genotype LR80, DNA vaccination reduced the overall probability of fish shedding, with a suggestive trend of the reduction being larger in single compared to mixed infections ( Figure 4 C; interaction virus × vaccine; LR80: Z 1,551 = 2.48, p = 0.013; Table S3A ).
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“a suggestive trend”
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p=0.06
In the literature
Among endothelial cell morphology indices, only lower hexagonality at 6 months after penetrating keratoplasty showed a suggestive trend of higher graft failure ( p = 0.02) [ 67 ].
However, there was a suggestive trend toward an increase in daily smartphone use (OR 4.10, 95% CI 1.15-14.6; P =.03) and the number of smartphone use purposes (mean difference 0.58, 95% CI 0.12-1.05; P =.01) among participants in the intervention arm.
Additionally, there was a suggestive trend of correlation between disease duration exceeding 10 years and FC between the left lobule VIIb and the left calcarine (R = 0.43, p = 0.034).
For three of the SNPs, there was no pattern towards earlier onset for the predisposing allele (rs4932196 p = 0.24, rs58389158 p = 0.75, rs2877561 p = 0.97); however, for SNP rs9493627 in EYA4, there was a suggestive trend (p = 0.044) towards earlier onset with the number of risk alleles.
There was a suggestive trend of a higher incidence of being overweight and obesity among the children with only a single time point ( p = 0.05), but this association did not remain statistically significant after adjustment for multiple testing.
Indeed, in control conditions there is a suggestive trend for a decline in sociability over time (effect of trial = −65.03 ± 31.45, F 1,19 = 4.28, p = 0.052) whereas fish measured under the risk context exhibit no such habituation (effect of trial = −37.8 ± 32.6, F 1,19 = 1.34, p = 0.26).
3c ), with a suggestive trend for decreased TERT expression for the VNTR6-1-Long allele (β = − 16.97 TPM, p = 0.053; Fig. 3d ).
A significant trend with respect to commuting increase (P = 0.05) was found at ages 0-14, and a suggestive trend (P = 0.055)) at ages 0-4.
Additionally, IL 10 tm mice had decreased creatine kinase (p = 0.018: Panel B in S8 Fig ) and a suggestive trend for decreased blood glucose (p = 0.055: Panel A in S8 Fig ).
Intermediate ADNC, P = 0.001), and a suggestive trend between Intermediate and High ADNC ( P = 0.055).
Finally, in the analysis of the total MFI score, as shown in Supplemental Figure S4a and b, blood samples showed a suggestive trend toward an association with homocysteine degradation (Holm p = 0.057, FDR = 0.032), although this did not reach statistical significance.
approached significancep = 0.059
For Time there was a suggestive trend, which on removal of the outlying individual approached significance [ F (1,8) = 4.82, MSE = 0.08, p = 0.059], whereby TP pre-WBPD ( M = 3.16, SD = 0.59) increased post-WBPD ( M = 3.37, SD = 0.53), in line with the hypothesis.
However, we noticed that systemic MDA concentrations were significantly decreased following SCO administration in LOS pre-treated mice, as compared to the control group ( Figure 5 a, LOS + SCO versus Control, p = 0.043), and had a suggestive trend as compared to the injury-positive control (LOS + SCO versus SCO, p = 0.06), leading to the assumption that the angiotensin II receptors blockage could prevent SCO-induced lipid peroxidation traceable from the blood sera.
Furthermore, histomorphological assessment of plaques from the Athero-Express study cohort, encompassing parameters such as macrophage content, SMC content, collagen content, and calcification, revealed a suggestive trend towards heightened CCN2 expression in plaques exhibiting elevated levels of ACTA2 + SMC content ( P = 0.06), albeit not with other parameters ( Figure 7 E ).
After incorporating right-sided extravalvular damage into our enhanced model, the AUC increased to 0.67 (95% CI, 0.53-0.80), reflecting a suggestive trend toward improved discrimination ( P = .06).
• A few lines later (lines 229-230), the authors report a lack of significant correlations between introgressed allele frequency and logFC values (despite a suggestive trend for Denisovan-introgressed alleles at p=0.06 which they do not explicitly comment). • In the discussion, (lines 442-445) they mention evidence of constraint against differential activity at high IAF for Denisova variants (despite the statistical significance of this observation has not been formall
HCC had a lower ADC than benign lesions, with a suggestive trend (p = 0.06).
Before adjustment for multiple comparisons [ 25 ], increasing PTV is significantly associated with increasing risk of SF at 18- and 54-month while at 36-month the association shows a suggestive trend ( p = 0.06).
There was a suggestive trend towards stronger associations between IL-6 and MDD with increased mean age ( p = 0.06).
However, antipsychotic treatment was associated with a significantly increased overall risk of common AEs (RR = 2.33 [95% CI: 1.63,3.34], p < 0.001; NNH = 17 [95% CI: 11,25]; Supplementary Figure 8 ); this increased risk was particularly evident for arousal-related AEs (RR = 2.77, p = 0.005) and other common AEs (RR = 2.03, p = 0.003), with a suggestive trend for EPS-related AEs (RR = 2.56, p = 0.06).
DLL3 H-score (cutoff 150) showed a suggestive trend for poor DFS (p = 0.06, hazard ratio (HR) = 1.90, 95% CI 0.98–3.70), independently of the other parameters.
There was also a suggestive trend toward high survival to adulthood by pupae with high encapsulation rates ( df = 1, Χ = 3.6, p = .06; Figure 4 a; Table S1 ).
However, FP236383.12 , encoding a non-coding RNA, showed a suggestive trend of increased expression (log 2 FC = 1.863, log 2 FCSE = 0.389 p = 0.064; Figure 1 a and Table 2 ).
Thirdly, the body of evidence on job stress and dissatisfaction could not demonstrate a clear association with mental health problems but only a suggestive trend, with nine of the 11 comparisons showing harm (82%, 95%CI [48%;98%], p = 0.065) ( Table 2 ) [ 26 , 31 , 35 , 38 , 41 , 42 , 46 , 48 , 49 ].