“a suggestive trend”

We further explored this correlation in each group, finding that it was not statistically significant in either alone but showed a suggestive trend of p = 0.066, and higher effect size, in the ULA group ( N = 52, r = 0.256, p = 0.066) rather than in the control group ( N = 31, r = 0.147, p = 0.431).

However, Neflamapimod treatment led to significantly reduced cerebrospinal fluid (CSF) levels compared to placebo, particularly in T-tau [difference (95% CI): -18.8 (-35.8, -1.8); P=0.031] and p-tau181 [-2.0 (-3.6, -0.5); P=0.012], with a suggestive trend for neurogranin [-21.0 (-43.6, 1.6); P=0.068].

While this trend was not significantly evident for dNLR, there was a suggestive trend (P=0.07) indicating lower efficacy in predicting clinical outcomes with the dNLR variable.

Fibroblasts from relatively long-lived species of birds were, similarly, found to be resistant to death induced by cadmium, paraquat, and MMS, with a suggestive trend ( P = 0.07) in resistance to H 2 O 2 .

There was a suggestive trend for increasing risk of mortality with higher intakes of saturated fat ( P =0.07).

However, there was a suggestive trend ( p < 0.07, two-tailed) for the control house ( M = 3.57, SD = 3.10) to contain more mirrors than the target house ( M = 1.00, SD = 1.41).

In terms of the PK of the first dose (before adjustment), the carriers of variant allele GSTA1 * B had a higher half-life, a higher C max , a higher AUC 0 –inf , a lower CL, and a suggestive trend of a lower Vd ( p = 0.071).

Nevertheless, MFI values exhibited a noteworthy progressive increase over the experimental periods ( p < 0.001), with a suggestive trend ( p = 0.074) for the interaction between the diet and period.

Despite a non-significant difference, there was a suggestive trend in mortality reduction for the SC+/cash group compared to cash-only group ( p = 0.076).

pylori infection; in fact, there was a suggestive trend in the opposite direction (ICD-10 B98: OR = 1.07; 95% CI: 0.99 to 1.16; P = 0.08; Backman et al. 2021 ).

For regression, SHANK3 showed a negative effect (p = 0.05) and the interaction term showed a suggestive trend (p = 0.082).

In addition, H89 administration alone did not alter PKA RIIβ expression; but a suggestive trend toward a decrease was noted (14.81 ± 7.8%, p = 0.087, not shown).

Results Distribution of the CARD8 p.C10X mutation (rs2043211) in the CD families and in control populations Allelic frequencies were not significantly different between the CD patients, the unaffected subjects (p=0.89) of the 39 CD families, the subjects from French control families and from the CEU panel of the HapMap version 3 release R2 (Table 1 ), but displayed a suggestive trend of association as analyzed by the CLUMP software (p=0.09).

After adjustment for age, nicotine use, and antipsychotic dose expressed in chlorpromazine equivalents, these differences remained statistically significant in serum ( p = 0.015) and showed a suggestive trend in plasma ( p = 0.09) [ 26 ].

No significant correlations were found between other personality traits ( Fig 2A and 2B ), even though there was a suggestive trend for a negative correlation between emergence times and our measure of sociability in males ( r p = -0.27, 95% CI [-0.73; 0.05], P = 0.09, n = 42).

Among all the HTN subtypes, reverse-dipper subtype was most significantly related to increased CSVD burden (OR = 1.725; 95% CI = 1.129–2.633; P = 0.012), whereas non-dipper subtype indicated a suggestive trend (OR = 1.387; 95% CI = 0.949–2.028; P = 0.091).

Subjects with high-risk MMs, characterized by the presence of HRCAs, had a suggestive trend toward worse OS compared with those with standard-risk MMs (HR, 1.7; 95% CI, 0.9-3.1; P = .1).

Additionally, those with a history of lower GI disorders showed a suggestive trend toward lower initial pain ( p < 0.1).

In the analysis of LC, none of the examined covariates reached statistical significance; however, there was a suggestive trend favoring higher radiation doses (> 54 Gy), which was associated with a reduced hazard of local recurrence (HR: 0.549, 95% CI: 0.258–1.164; p = 0.118).

There was also a suggestive trend for CD patients with NOD2 variant alleles and pediatric-onset towards osteoporosis (p=0.12, Figure 1 ; and by multivariate analysis p=0.07) and low BMD (Z-score below −1 p=0.10; Table 2 ).

Although with a suggestive trend, the association of two SNPs was not significantly correlated with anti-PLA2R levels ( P = 0.163 for rs2187668 and P = 0.184 for rs28383345) [ Table 5 ].

There was a suggestive trend for increased litter size in FMT-EF mice ( P value ~ 0.1726; Fig. 4c ).

With regards to EGFR TP53 comutations, there was a suggestive trend towards higher prevalence in women (42/69, 60.87% vs. 15/33, 45.45%, p= 0.2007; q= 0.2007) in HR+ NSCLC.

Genetic redundancy could also be predicted to influence the phenotypic outcome of mutating single genes, and there is a suggestive trend consistent with this idea in our dataset (Fisher's exact test, p-value = 0.2117), with 6/7 non-Mendelian alleles classified as singletons in the maize genome (86%), compared to 14/25 singletons in genes harboring Mendelian alleles (56%) (Tables 1 and 2 ).

SHOX2 methylation in plasma correlated significantly with tissue levels (Spearman’s p = 0.36, P = 0,007), while SEPT9 showed a suggestive trend (Spearman’s p = 0.25, P = 0.067).