“a strong trend”

Repeat kidney biopsies of four SjD-TIN patients at a median of 549 days after treatment initiation showed a strong trend (p = 0.077) towards improvement in tubulitis, indicating clinical effects of the prescribed treatment on SjD-TIN-activity (Fig. 4 a).

Prior tumor control ≥ 12 months showed a strong trend toward improved OS (β = 2.10, OR 8.20, 95% CI 0.80–165.68, p = 0.077).

However, consistent with the decreased BDH1 protein (Figure 1C ) and trend in decreased BDH1 enzyme activity (Figure 1E ), there was a strong trend for decreased KB utilization in isolated working hearts (Figure 1N , P =0.077).

Difference in PCSK9 levels, from baseline to 8 and 13 weeks, between the supplementation and placebo group showed a strong trend of PCSK9 decrease only in patients with favorable lipids changes in the supplemented group ( p = 0.077).

There was a strong trend toward longer survival for octogenarian nonsmokers compared with octogenarian ex-smokers/smokers (mean overall survival 21.2 vs 12.2 months; p =0.0770).

Regarding the effect of the type of device, in Cluster 2 “Assessed/Younger” phenotype, pre-admission use of a Spacer was associated with a strong trend towards an increased risk of errors ( p = 0.077), and pre-admission use of a DPI was associated with a modest, non-significant reduction in errors ( p = 0.11).

Further, those who reported higher levels of social WB during the CanWell program showed a strong trend towards being more likely to continue and exercise following the supervised exercise program ( P =0.077).

Importantly, GREs were significantly more enriched at GC-specific active STARR-seq sites in 697 cells compared to 0 h-specific active STARR-seq sites (Chi-square p = 1.3 × 10 −4 , 1.5-fold) and exhibited a strong trend for greater enrichment in Nalm6 cells (Chi-square p = 0.077, 1.6-fold).

The main findings of the current study reveal that a gluten-free (GF) meal is: (1) significantly ( p < 0.01) more thermogenic efficient compared to ultra-processed (PF; −41%) and unprocessed whole food (WF; −50%) meals, respectively; (2) WF meal consumption resulted in significantly ( p < 0.01) greater feelings of fullness compared to GF (+14.36%) and PF (+16.81%), respectively, and enhanced ( p < 0.05) palatability (taste of meal) compared to PF meal (+27.41%); and (3) there was a strong trend ( p = 0.077) for increased desire to eat following the PF compared to WF at 120 (+26.42%) and 180 (16.62%), respectively.

There was also a significantly lower expression of leptin in PAT compared to gWAT ( p < 0.05) and a strong trend towards a lower expression level of leptin in PAT compared to iWAT ( p = 0.0771).

Recovery was also significantly increased in irradiated mice if a recovery threshold of 100% was imposed ( P = .0230), and a strong trend was observed at 96% ( P = .0776) ( Table E2 ).

However, due to the crossover nature of the study, each individual served as their own control, and the effect size was big enough that a strong trend was observed for the 24‐h urinary excreted amount of CCM (fourfold increase, p = .0776) and half‐life (twofold increase, p = .0527).

Similarly, a significant diet effect was revealed for the AUC of 60 min of glucose tolerance test in absolute values and in percent to basal glucose level (F = 11.92, p = 0.0033 and F = 8.51, p = 0.0101, respectively) without significant genotype effect (F = 0.06, p = 0.805 and F = 0.809, p = 0.381) but with a strong trend for their interaction (F = 3.53, p = 0.078 and F = 3.57, p = 0.077, two-way ANOVA).

Metformin treatment also showed a strong trend towards enhanced posterior wall thickness compared to SD hearts ( p = 0.078).

Furthermore, there was a strong trend that higher non‐classical monocytes at sea level were found in participants who had AMS on day 1 at high altitude ( t (9.48) = −2.0, p = 0.078).

Middle cerebral artery M2 locations demonstrated a strong trend favoring endovascular coiling that did not reach statistical significance (WR = 2.50, 95% CI: 0.97–6.44, p = 0.078), likely due to limited sample size.

Enhanced ATGL protein levels in the mutants were accompanied by a strong trend (p=0.078) towards increased Atgl mRNA levels after fasting ( Figure 2D ). iBAT from fasted conditional mutant mice also showed a significant decrease in the mRNA levels of G0/G1 switch gene 2 ( G0S2 ), which encodes an inhibitor of ATGL activity ( Yang et al., 2010 ; Figure 2E ).

The average size of Myh3-positive objects was determined and it was found that the TA (A) exhibited a strong trend for a delay in the growth of Myh3-positive cells (P = 0.078), while the delay in growth in the gastrocnemius (GAS) (B) was statistically significant (interaction: P<0.05).

2.56 μg/ml [2.24-4.26]; p = 0.0351) as well as a strong trend towards lower levels of sCD40L (2.70 pg/ml [1.90-4.00] vs. 3.60 pg/ml [2.95-5.30]; p = 0.0782) (Figure 3B ).

Patients with anti‐Scl‐70 autoantibodies had a strong trend toward having progressive disease ( P = 0.0783), whereas patients with anti‐centromere (ACA), anti‐U1 or anti‐U2, and anti‐Th or anti‐To antibodies were associated with less progressive disease ( P = 0.1796 for each; Table 1 ).

This association in all patients with CHF was triggered by a strong trend in the cCHF subgroup (r = 0.53, p = 0.079) and was not significant in ncCHF patients (r = 0.13, p = 0.6).

They suggested that intravesical instillation chemotherapy might be a useful approach for reducing the risk of bladder recurrence, but their results only demonstrated a strong trend ( P = .079) rather than a significant difference.

The relationships between the PSO-based dietary pattern and placental weight and PDI scores were no longer statistically significant in the sensitivity analysis, although a strong trend remained (Adjusted P = 0.079 and Adjusted P = 0.085, respectively).

We also found an increase in CD11b + granulocytes (mean difference: 11.82, 95% CI: 0.207 – 23.43, two-tailed t-test p=0.0475) in GM-CSF-treated mice ( Figure 3D , Supplementary Figure S2D ), which was generally accompanied by a strong trend toward increased neutrophils (mean difference: 13.85, 95% CI: -2.555 – 30.26, two-tailed t-test p=0.079) vs placebo-treated mice ( Figure 3E , Supplementary Figure S2E ).

Figure 4E ) a strong trend was also observed after overnight fasting (p = 0.079; Suppl.