Barely Significant
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“a strong trend”

5,726 sentences · 5,726 papers · 7,352 search hits before verification · confirmed specimen

Sighted at

p=0.077

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

a strong trendP = 0.081.6× alphagold
suggested that multiple ACPA reactivities (≥2 vs 0–1) was a significant risk factor (odds ratio 2.1; 95% CI: 1.0, 4.4; P = 0.04) with a strong trend of prediction for arthritis development (HR: 1.7; 95% CI: 0.93, 3.16, P = 0.08) in the Risk-RA phase [ 23 ]; and we can in this study report a significant predictive value of presence of ACPA reactivity (≥1 vs 0) for arthritis (HR 8.0; 95% CI: 2.9, 22; P < 0.001).
a strong trendp = 0.081.6× alphagold
Of note, we found a strong trend towards improvement of perfusion (0.80±0.04 LDI ratio (r/l), p = 0.08) ( Fig. 4A,B ) in the rAAV.APLN+Ang2 (d0-3) group, which co-incided with improved CMF-R (1.59±0.02) compared to rAAV.APLN only and improved PC-R (0.67±0.01), compared to rAAV.APLN+Ang2 ( Fig. 4C–E ).
a strong trendp = 0.081.6× alphagold
However, when we evaluated MMP-9 and MMP-2 activity in EDL homogenate (EDL muscles have a similar fiber type composition to TA muscles) via gelatin zymography, we found a strong trend for IRI+BGP treatment to increase MMP-9 activity relative to VEH ( p = 0.08; Figure 4 J,N) whilst also significantly reducing MMP-2 activity compared to VEH and IRI treatments ( p < 0.05; Figure 4 K,N).