High responders also showed a strong trend toward longer average daily duration of meditation (median: 11.8 minutes vs 7.9 minutes, P =0.079) and higher average exercise–NMES adherence (median: 85.9% vs 73.3%, P =0.109) than low responders ( Figure 4C and D ).
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Figure 4E ) a strong trend was also observed after overnight fasting (p = 0.079; Suppl.
HLA-A*24:02 + HLA-A*202:01 − patients showed a strong trend for improved OS than HLA-A*24:02−HLA-A*02:01 + patients (zero vs. seven deaths at four years postdiagnosis, respectively; Gehan-Breslow, p = 0.0794) ( Figure 2 c). 2.3.
A strong trend for its increase in the stressed non-treated group compared to that in the control group was found ( p = 0.0798, Tukey’s test).
The proportion of Gram-negative bacteria showed a strong trend toward being higher in the Summer group (50.7%, 34/67) compared to the Winter group (35.1%, 20/57) (X 2 = 3.068, p = 0.080) ( Figure 1 ).
Whilst for most products individual variation was too high to yield statistical significance, for both CSF3 and CXCL10, there was a significant ( p < 0.05 ) reduction upon mating with Rln −/− males, reflecting that seen at the mRNA level, as also a strong trend to reduction for CXCL1 ( p = 0.08).
suggested that multiple ACPA reactivities (≥2 vs 0–1) was a significant risk factor (odds ratio 2.1; 95% CI: 1.0, 4.4; P = 0.04) with a strong trend of prediction for arthritis development (HR: 1.7; 95% CI: 0.93, 3.16, P = 0.08) in the Risk-RA phase [ 23 ]; and we can in this study report a significant predictive value of presence of ACPA reactivity (≥1 vs 0) for arthritis (HR 8.0; 95% CI: 2.9, 22; P < 0.001).
More interestingly, patients with low miR-210 without necrosis show a strong trend that CON treatment may not be suitable (5-year OS was 55.3% for RT and 24.3% for RT+CON, log-rank P =0.08, HR 0.51, 95% CI 0.24–1.09; Figure 4B ).
1 ) show a strong trend for improved survival in the OE mice compared to WT (3 deaths from n = 30 OE mice vs. 9 deaths from n = 33 WT, P = 0.08), in particular, within the first 10 days post-surgery.
In three independent preparations, no difference in pERK1/2 abundance could be detected ( Fig 10A and 10B ), however, 20 nM prorenin caused a strong trend towards increased ERK1/2 phosphorylation (p = 0.08).
Despite this, there appeared to be a strong trend and it raises the possibility that the combination treatment may be more efficacious (66% vs 86%, p = 0.08) than administering methotrexate alone but we were underpowered to detect this.
After adjustment for baseline QoL scores, participants in the UC HAT arm had a strong trend toward decreased Seo index scores from baseline (mean –11.9, SD 6.6; P =.08).
A significant increase from baseline was observed at 3 h post-injection, with a strong trend to increased scores ( p = 0.08) observed at 6 h.
This effect was significant for Specific recognition, [ t (42) = 2.0, p < 0.05], and emerged as a strong trend for Overall recognition, [ t (42) = 1.8, p = 0.08].
Of note, we found a strong trend towards improvement of perfusion (0.80±0.04 LDI ratio (r/l), p = 0.08) ( Fig. 4A,B ) in the rAAV.APLN+Ang2 (d0-3) group, which co-incided with improved CMF-R (1.59±0.02) compared to rAAV.APLN only and improved PC-R (0.67±0.01), compared to rAAV.APLN+Ang2 ( Fig. 4C–E ).
Despite a strong trend, there was no significant difference between control fish and those treated with 1% alcohol ( P = 0.08, M = 19.77, SD = 13.32).
There was a strong trend for LDM DOX treatment to reduce wheel running activity between the PRE and POST periods compared to VEH (p = 0.08; Fig. 2 A,B) and this effect was significant in the DOX + SN group ( p < 0.05; Fig. 2 A,B).
Blinded analysis revealed that SCN10A −/− /CaMKIIδc +/T showed a strong trend towards a reduction of premature ventricular contractions (PVC) by ~93% compared to CaMKIIδc +/T (Fig. 6a, c , p = 0.08).
However, when we evaluated MMP-9 and MMP-2 activity in EDL homogenate (EDL muscles have a similar fiber type composition to TA muscles) via gelatin zymography, we found a strong trend for IRI+BGP treatment to increase MMP-9 activity relative to VEH ( p = 0.08; Figure 4 J,N) whilst also significantly reducing MMP-2 activity compared to VEH and IRI treatments ( p < 0.05; Figure 4 K,N).
There were no correlations ( P > 0.05) between age, Hb, and LVEF with V̇O 2peak or other CPET variables, although Hb showed a strong trend with V̇O 2peak ( r = 0.38; P = 0.08).
This correlation was significant according to Pearson’s test (NAc-sh, r = 0.64, p = 0.025; OB, r = 0.63, p = 0.027) and showed a strong trend according to Spearman’s test (NAc-sh, r = 0.52, p = 0.08; OB, r = 0.57, p = 0.06; Figure 4 J).
In agreement with earlier reports, we observed lower phagosome maturation following FcR-mediated phagocytosis in HIV infected persons compared to HIV negative subjects, although the difference was not significant but rather a strong trend ( p = 0.08 at 10 min and p = 0.06 at 120 min).
Cognitive status significantly moderated the association between plasma biomarkers and ERC volume for both p-tau181 (β = −0.39, p = 0.04) and NfL (β = −0.44, p = 0.03), with a strong trend for GFAP (β = −0.46, p = 0.08).
A strong trend was also observed in the 12-week training group (p = 0.08) compared to their matched 12-week sedentary control.
In another model of human disease, we found significantly higher levels of Thbs1 mRNA and a strong trend ( P =0.08) towards higher levels of TSP-1 protein in whole-lung lysates from newborn calves with chronic hypoxia-induced PH ( Fig. 5d and Supplementary Fig. 27 ).