Accordingly, there was a strong trend towards a longer time to diagnosis in patients who died compared to those who survived (8.8 ± 11.1 vs. 4.5 ± 6.8 days, p = 0.071).
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In the literature
[ 21 , 50 ] Among astrocyte‐enriched synaptogenic factors, Thbs1 (encoding TSP1, an established astrocyte‐secreted protein that promotes excitatory synaptogenesis [ 32 ] ) showed a strong trend toward lower expression in PERK cKO mPFC tissue ( P = 0.0715; Figure 6E ), although this did not reach statistical significance.
Furthermore, among advanced-stage patients, the sufficient-dose A-AVD group showed a strong trend toward improved PFS compared with the ABVD cohort (2-year PFS 91.7% vs. 65.8%; log-rank p = 0.072; Figure 2E ).
Additionally, there is a strong trend on relational alliance ( p = 0.072).
Despite a strong trend in the same direction, CTNNB1 mutations showed no statistically significant association with higher hazard ratio (HR) of PSA progression (HR 2.12, p = 0.072) [ 24 ].
Moreover, the intracortical injection of the control IgG1 or rCD300f-IgG1 into CD300f −/− mice showed a strong trend towards increasing the lesion volume when compared to WT mice injected with control IgGs (40 ± 4% increased lesioned hemisphere, p = 0.072 or 40 ± 3% increased lesioned hemisphere, p = 0.052 respectively) (Fig. 4 C), suggesting that the absence of CD300f is neurotoxic after a penetrating brain injury.
Patients with ER expression ≥90% showed a strong trend toward longer OS (49.0 vs. 41.0 months; p = 0.072).
In gemcitabine-treated early-onset disease, TP53 mutations were present in 86.7% of tumors, compared with 40.0% in non-treated early-onset tumors ( Table S5 ), representing a strong trend that did not meet statistical significance in this small subgroup ( p = 0.0726).
NOLT of AL showed a strong trend towards higher success rates than surgical management of AL (76.9 vs. 52.4%; p = 0.073) with no significant differences between early or late AL treatment.
Along, a strong trend of less severe post-operative complications in general ( p = 0.073), and borderline-significantly less cases of acute pancreatitis ( p = 0.057) and tAMP-related re-operations or re-interventions ( p = 0.057) in particular, were observed in the eVAC-CPI-group.
In addition, a significant decrease in countermovement jump was observed for CON (–6.7 ± 7.1%; ES = –0.57 ± 0.32; P = 0.003) and a strong trend for a decrease was identified for CGs (–4.2 ± 8.4%; ES = –0.31 ± 0.26; P = 0.073) following DHR.
Interestingly, we observed a strong trend towards a lower MMA ( p = 0.073), suggesting a higher amount of muscular fat deposition in patients with more advanced tumor stage ( Supplementary Materials Figure S2B ) as well as a significant stepwise reduction of the MMA in patients with an increasingly impaired ECOG PS ( Supplementary Materials Figure S2C ).
Surprisingly, the features of single spikes fired to a threshold 10-ms current pulse were no different between control and depolarized groups ( Figures 6 C and 6D; Table S1 ), despite a significant depolarization-induced drop in input resistance ( Evans et al., 2013 , Grubb and Burrone, 2010 , O’Leary et al., 2010 ; Table S1 ; Mann-Whitney test, p = 0.044, n = 68) that produced a strong trend toward elevated rheobase in the +15-mM KCl group ( Table S1 ; Mann-Whitney test; p = 0.073, n = 32).
In addition, 12 Gy × 3 reduced intratumoral pressure 1 day after XRT ( P = .0203), and had a strong trend of decreasing pressure on day 3 ( P = .073).
ANOVA conducted with the factors GROUP (Controls, MIA) and iTBS (pre, post) after sham- or verum-iTBS had been applied revealed no significant effect of factor GROUP but a significant effect of factor iTBS in case of sham-iTBS ( F (1,25) = 5.824, p = 0.025, η 2 = 0.209) and a strong trend in case of verum-iTBS ( F (1,25) = 3.569, p = 0.073, η 2 = 0.151).
38.5%, p = 0.008), and a strong trend toward improved pCR was observed (34.0% vs. 21.8%, p = 0.073).
Sp) and a strong trend ( p = 0.0739) toward a significant impact on the cortical bone parameters ( Figures 1H, I : Ct.
Additionally, a VAF ≥ 53% was a significant risk factor for OS ( P = 0.007) and showed a strong trend for PFS ( P = 0.074).
Physical triggers and malignancies were related to biventricular impairment (p = 0.004 and p = 0.026), showing higher dyssynchrony (p < 0.01), greater reduction of left ventricular function (p < 0.001) and a strong trend towards increased mortality (p = 0.074).
Patients with strong Ido1 expression in the neoplastic epithelial cells showed a strong trend ( p = 0.074) towards bad prognosis.
In unadjusted Kaplan–Meier pairwise comparisons, Q4 survival was significantly worse than Q2 ( p = 0.045) and showed a strong trend toward worse survival compared with Q1 ( p = 0.074).
In contrast, the mean number of links measured at DIVs 14 and 21 was lower than at DIVs 28 and 35, with a strong trend towards a significant increase between the younger and older ages (P = 0.074).
The t-test shows a significant effect for comprehenders (p = 0.003, df = 14, random rectangle MEAN = 15, SD = 10.64; fixed picture MEAN = 35, SD = 10.64) and a strong trend for non-comprehenders (p = 0.074, df = 8, random rectangle MEAN = 16.67, SD = 12.19, fixed picture MEAN = 33.33, SD = 12.19).
Additionally, an increase in respiratory rate demonstrated a strong trend, albeit with borderline statistical significance (OR: 1.099; 95% CI: 0.991–1.218; P = .074) (see Table 4 ).
Although there was a strong trend, previous surgery of the affected shoulder did not significantly increase the risk for iatrogenic nerve injury per se (RR 1.23, 95% CI 1.02–1.75; p = 0.074).