Real-World Predictors of Survival in CDK4/6 Inhibitor-Treated Metastatic Breast Cancer: The Significance of ER Expression Level and Treatment Naivety.

Curr Oncol · 2025 · PMC12732278 · PMID 41440236

Europe PMC DOI

hedged sentences

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

a trend towards significancep = 0.072so close (0.05 < p ≤ 0.1)

Although ER expression ≥90% showed only a trend towards significance in univariate analysis (49.0 vs. 41.0 months; p = 0.072) ( Figure 8 ), it was included in the multivariate model based on our pre-specified hypothesis.

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a strong trendp = 0.072so close (0.05 < p ≤ 0.1)

Patients with ER expression ≥90% showed a strong trend toward longer OS (49.0 vs. 41.0 months; p = 0.072).

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