“a strong trend”

In an independent validation cohort of 258 R-CHOP treated patients with de novo DLBCL, elevated beta-2 microglobulin levels remained a significant poor prognostic factor for PFS (HR, 2.03; 95% CI, 1.23–3.32; p = 0.005) and exhibited a strong trend of association with worse OS (HR, 1.64; 95% CI, 0.98–2.75; p = 0.062).

E-E groups ate less during 24h and showed a strong trend towards a decrease during night (p=0.062), compared to V-E A groups.

Doppler measurements of blood flow across the mitral valve showed a detrimental increase in the myocardial performance index (MPI, a measure of combined systolic and diastolic function) in 10-week-old male SMGRKO mice ( P < 0.05), with a strong trend for an increase in MPI in females ( P = 0.062, Fig. 2 ).

We further observed both a significant cell cycle phase arrest ( p = 0.040) and the promoting of cellular apoptosis ( p = 0.016) as well as a strong trend ( p = 0.062) for an inhibition of nuclear import of c-Myc.

A Fisher’s exact test demonstrated a strong trend toward statistical significance for this disparity (p = 0.0621).

With the data collected in the anamnesis, we found that mothers of infants in the ankyloglossia’s group reported significantly more pain complaints (64% versus 22%, p= 0.0094), and there was a strong trend towards more reported long feedings (43% versus 16%, p=0.0623).

However, there was a strong trend ( P = 0.0625) toward increased bacteremia in mice inoculated with LasB compared to EF3030 alone ( Fig. 3B ).

However, a strong trend towards more extensive Safranin-O-stained regions was observed in the P188 constructs ( p = 0.0625) ( Figure 2 f), indicating enhanced proteoglycan deposition.

Results showed that female mice exhibited a strong trend for an increase in PR breakpoint [ t (14) = 1.63, p = 0.0627; Figure 4H ] as well as corresponding significant increases in PR session duration [ t (14) = 2.1, p = 0.027] and number of headpokes per session [ t (12) = 2.02, p = 0.033; Figures 4I , J ].

6.0 ± 11.0; p = 0.015) as well as a strong trend in the total length of stay ((in days) 13 ± 12 vs. 15 ± 28; p = 0.063).

Interestingly, a highly dissociative pattern was obtained for the two-way interaction effects: PD Diagnosis showed a strong trend for an interaction with Goal Ambiguity ( F (1,56) = 3.61, p = .063) but not with Search Depth ( F (1,56) = .03, p = .868), whereas SD Impairment showed a significant interaction with Search Depth ( F (1,56) = 20.74, p <.001) but not with Goal Ambiguity ( F (1,56) = .18, p = .672).

After six weeks of administration, the β-diversity profiles of fecal microbial composition in subjects showed a strong trend toward significant difference between the TWK10 and TWK10-hk groups (PERMANOVA, P = 0.063), based on NMDS analysis with unweighted UniFrac metric ( Figure 3 B).

In the rituximab monotherapy group, significant decreases were observed only after two doses of SUV max , SUV mean , MAV, CT rim and CT cc ( p = 0.028–0.046) with a strong trend towards improvement also in SUV peak ( p = 0.063), while after application of only one dose there was no significant response ( p = 0.109-1.000).

At the 100 ms ISI, there was a strong trend for reduced sensitivity to the disruptive effects of AMPH in METH-treated mice of both sexes (Figures 3C,D , AMPH × METH treatment interaction p = 0.063).

The COMT Val108/158Met genotype demonstrates a strong trend towards predicting the range of the NRG1α-induced adhesion response with risk homozygotes having decreased variation in cell adhesion even in normal subjects (p = 0.063).

At the two-year follow-up, there was a strong trend toward fewer TLRs in the de novo group (5.3%) compared to the ISR group (10.2%) ( p = 0.063) ( Table 3 and Figure 1 ).

The CGI-S showed a trend toward improvement over placebo in the arbaclofen group ( p = 0.063) but this was the only measure showing a strong trend, and given the multiple comparisons, this result alone is difficult to interpret as meaningful.

Regarding Salmonella isolation, granivorous diets were significantly protective compared to carnivorous/scavenger diets (OR = 0.14, p = 0.004), while non-wild (anthropized) habitats showed a strong trend toward increased risk (OR = 12.29, p = 0.063), as reported in Supplementary Materials, Table S10 .

HPV negativity and high abundance of B cell/CD8 + T cell interactions in the tumor nests did not reach statistical significance, but there was a strong trend ( p = 0.063, HR = 0.29, 95% CI = 0.08–1.06 and p = 0.068, HR = 0.11, 95% CI = 0.01–1.17; respectively).

In the multivariate analysis, high NK activity showed a strong trend toward improved overall survival (HR, 0.52; 95% CI, 0.26–1.04; p = 0.063).

Costs associated with the transfusion of blood products were significantly higher in patients with target attainment (€90.60 and €12.70, P = 0.023), with a strong trend toward higher RRT costs in this patient category (0 and 0, P = 0.063).

However, there was a strong trend for proven CMV colitis as a risk factor for steroid-refractory UC based on univariate analysis (OR, 2.47; 94% CI, 0.95–6.40; P = .063).

Cross-generalization between stimulus and template neural patterns Training the population tuning-curve weights on template orientations around the time of stimulus onset (–150 to +300 ms) showed a strong trend toward generalizing to stimulus decoding shortly after onset ( Figure 5A , 52–124 ms, corr. p = 0.063).

However, there was a strong trend for total cover ( F 1,4 = 6.499, P = 0.063) and spinifex cover ( F 1,4 = 7.464, P = 0.052) to be greater in areas where grazing intensity had been historically light rather than heavy.

No significant difference was observed in the frequency of cells expressing the classical immune checkpoint PD-1, although a strong trend in the CD8 + T cell compartment was observed (Fig. 2 f, P = 0.063, Welch’s t-test).