On multivariable analysis, however, this effect only showed a strong trend (HR 2.11, 95% CI −0.10, 4.32; p = 0.061).
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Also, when SLIT participants who ceased to show a reaction to the CPT after 4 weeks of treatment were compared with placebo-treated participants, there was a strong trend towards lower RTSS 14 ( P = 0.061), RTSS 30 ( P = 0.081), and RTSS 60 ( P = 0.067) values for nonreactive SLIT participants (Table 5 ).
Mediastinal (N2) station sampling showed a strong trend toward more thorough dissection in the uRATS group (median 4 stations [IQR 3–4] vs. 3 [IQR 2–3]; p = 0.061; Figure 5 C).
While co-treatment failed to reach strictly defined statistical significance, it did produce a strong trend toward increased survival (p = 0.0611), and 50% (5/10) of the animals displayed CR compared with no animals (0/5) in the rRp450-alone-treated group.
Baseline LV characteristics GHD patients demonstrated a strong trend towards reduced LVMi (51.4 ± 3.2 vs. 60.0 ± 2.8 g/m 2 , p = 0.0615; Fig. 1 ) .
The five sites that remained associated with three different genes, two of which showed a significant difference in expression between samples from COPD and non-COPD donors ( OAT and GRIK2 ) and a third that displayed a strong trend ( p = 0.0618) toward differential expression ( TRPV3 ).
P value was calculated using 2X2 table for the presence or absence of dramatically expanded CAG repeats in cases and controls (5 versus 207 in cases and 0 versus 96 in controls) Although statistically not significant, the Fisher exact test suggests a strong trend with border line significance (p = 0.0619).
Brain MeSH levels were also not significantly different between experimental groups and sham-kindled mice, but there was a strong trend for a main effect of stimulation ( Figure 4 B; F (3,35) = 2.683, p = 0.062).
Furthermore, ITRCZ-Cht NPs exhibited a strong trend towards significance compared to plain ITRCZ regarding hepatocyte survival rate ( p = 0.062) and LDH activity ( p = 0.064).
When examining the time in the center of the open field (as a measure of anxiety), there was a strong trend in overall difference between groups (Kruskal–Wallis ANOVA: p = 0.062; saline: mean duration, 164.3 ± 2.8 s; dKA: mean duration, 151.9 ± 2.9 s; vKA: mean duration, 114 ± 4.4 s) and individual comparisons exposed a significant difference between the vKA and saline groups (Mann–Whitney test, p = 0.024) but not between the dKA and saline groups (Mann–Whitney test, p = 0.58; Fig. 4 c ).
Body composition For total body mass, both groups increased with training (p = 0.001) with a strong trend for NO to be significantly greater than PL (p = 0.062).
In this study, the combination of Depatux-M with temozolomide (TMZ) demonstrated a strong trend towards substantial benefit in overall survival compared to the chemotherapy arm (HR 0.71, p=0.062) ( 57 ).
In 1.75–2 g, a strong trend for lengthening was observed (+11.5%, p = 0.062).
There was a significant effect of time (P < 0.001) and a strong trend toward a significant time x group interaction (P = 0.062) for plasma PC ARA.
Dovitinib did not regulate TGFB1 gene expression, there was a strong trend towards downregulation of SEMA3A (Dovitinib vs. control: p = 0.062) ( Figure 8 A,B). 4.
Conversely, the oldest age group (50 or older) showed a strong trend toward higher odds of a Non-Positive CAB score, nearly twice those of the 18–25 group (OR = 1.92, 95% CI [0.97, 3.80], p = 0.062).
A strong trend for reduced biofilm formation was observed for the mutant lacking psrP-secY2A2 ( P = 0.062).
A strong trend toward a positive association was observed between antihypertensive medications and RSF ( P = 0.062).
The difference between groups at week 26 showed a strong trend towards statistical significance (p=0.062) by the unconditional z-pooled test, figure 1 A.
In KYNA there was no significant difference, but a strong trend p = 0.062 (0.69 ± 1.54 in the VitD group compared to −0.23 ± 1.31 in the PL group; Figure 4 a) was observed.
In an independent validation cohort of 258 R-CHOP treated patients with de novo DLBCL, elevated beta-2 microglobulin levels remained a significant poor prognostic factor for PFS (HR, 2.03; 95% CI, 1.23–3.32; p = 0.005) and exhibited a strong trend of association with worse OS (HR, 1.64; 95% CI, 0.98–2.75; p = 0.062).
Overall, there was a strong trend toward more cell proliferation or clone expansion associated mutations in CD59- cells than in CD59 + cells ( p = 0.062) (Supplementary Table S3 ).
In addition, there was a strong trend for significantly higher levels for WL compared to WS for vitamin B12 (p=0.062).
We further observed both a significant cell cycle phase arrest ( p = 0.040) and the promoting of cellular apoptosis ( p = 0.016) as well as a strong trend ( p = 0.062) for an inhibition of nuclear import of c-Myc.
Doppler measurements of blood flow across the mitral valve showed a detrimental increase in the myocardial performance index (MPI, a measure of combined systolic and diastolic function) in 10-week-old male SMGRKO mice ( P < 0.05), with a strong trend for an increase in MPI in females ( P = 0.062, Fig. 2 ).