“a significant trend”

2 a ) further supported a significant trend toward higher ω values (indicative of relaxation of selection) in lungfish (Mann–Whitney U test, P < 0.01).

Patients with grade 2/3 neutropenia were significantly younger (mean age 48 years) than those with grade 4 neutropenia (mean age 52 years, P <0.002), and overall there was a significant trend for higher grades of neutropenia in older patients ( χ 2 for trend=6.87, P <0.01).

The improved parameter calculation and automated and objective quality assessment resulted in a significant trend ( p < 0.01) when applying the tolerant quality criteria, which translates into a NMCdi decrease of 4.3 percentage point (pp) per cmH 2 O of PEEP relative to a PEEP of 3 cmH 2 O.

As the main results of this study, pancreatic cancer cases showed a trend for a higher median of 8-OHdG as well as a significant trend when the level of 8-OHdG was categorized in Quartile scale [1.50 (1.09, 2.06) (P=0.01)].

Notably, a significant trend of increasing mortality was observed across SDoH categories, with higher mortality rates in the high SDoH group ( P < .01).

However, this better prognosis was time dependent with a significant trend toward late recurrence with ILC compared to IDC ( P < 0.01). 3 Rakha et al 4 showed that ILC has an indolent but progressive clinical course with nearly linear survival curves which cross those of IDC after approximately 10 years of follow up, thus eventually exhibiting a worse long-term outcome.

18 A significant trend was also observed when stratified by duration of employment ( P <0.01); for the workers employed 20–32 years, lung cancer risk was five times that expected (SMR=502, 95% CI 305–698).

We observed a significant trend ( p -value < 0.01).

In the AMI total score, referred to Q1 group, Q3 and Q4 groups were associated with reduced aOR of sarcopenia with a significant trend after adjusting for all covariates (aOR 0.69–0.71, both P < 0.01).

Plasma NGAL levels also increased progressively with AKI stage: 481.6 ng/mL (stage 1), 625.5 ng/mL (stage 2), and 760.2 ng/mL (stage 3), showing a significant trend ( P < 0.01).

The Cuzick extension of the Wilcoxon's rank sum test confirmed the presence of a significant trend of increasing MCM-2 and MCM-5 expression with increasing tumour stage ( P =0.0100 and 0.0300, respectively).

Similarly, there was a significant trend in all item scores (with the exception of environmental autonomy) across the cognitive subgroups (all p<0.01).

Compared to controls, S-losers had significantly lower plasma anti-HBc levels prior to HBsAg seroclearance, with a significant trend of declining plasma anti-HBc 8–5 years prior to HBsAg seroclearance (p < 0.01), while such trend was not observed in controls.

Results Patients at high altitudes showed a significant trend toward lower age (61.0 ± 10.2 vs. 64.8 ± 8.1, P = 0.010) and had a history of dyslipidemia, higher levels of inflammatory markers, erythrocytosis, and alcohol abuse.

When we grouped the patients according to their genotype and S-MBL above or below the median for their genotype (high/above [ n = 78], high/below [ n = 78], low/above [ n = 65], and low/below [ n = 66]), there was a significant trend among the four groups to predict survival free from cardiovascular event (log-rank test P = 0.01) ( Fig. 1 ).

Based on the biomarker values related to serum L-fucose levels in this study, a significant trend (P < 0.01) was observed with the progression of OSMF (C) ( Table 2 ).

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

In the >4 weeks treatment duration subgroup, meta-analysis indicated a nonsignificant trend for reduction in SBP between experimental and control groups [WMD = 0.55, 95% CI (−2.63, 3.72), P = 0.735]; however, in the subgroup with treatment duration ≤ 4 weeks, there was a significant trend for reduction between the two groups [WMD = −4.42, 95% CI (−6.29, −2.20) P < 0.01] ( Figure 7 , Supplementary Figure 10 ) .

The Global Moran’s I analysis showed a significant trend towards clustering (Moran’s Index = 0.29; z-value = 6.78; p -value < 0.01).

Similarly, the Social Vulnerability Index showed a significant trend for the percentage of those without a high school diploma (β = 0.02, p<0.01).

A significant trend towards a higher citation count with article age was observed (r = 0.832, p < 0.01) ( Figure 1 A).

There was a significant trend of increasing the production of TNF- α , IL-6, IL-1 β , and IL-10 in RAW 264.7 cells stimulated by 1 μg/mL LPS, as shown in Figure 5 ( p < 0.01).

The results of the meta-analysis demonstrated that there was a significant trend towards a lower risk of objective incidence [67%; risk ratio (RR), 0.33; 95% confidence interval (CI), 0.16–0.67; P<0.01] and subjective incidence (66%; RR, 0.34; 95% CI, 0.16–0.75; P= 0.01) of Frey syndrome in the SCMF group.

[ 63 ], conducted a case-control study in the USA and found a significant trend for increased breast cancer risk in post-menopausal women exposed to high PAH levels at birth ( P = 0.01), with ORs ranging from 1.94 to 2.42, suggesting a dose-response relationship.

Additionally, one-way ANOVA demonstrated a significant trend in elevated LAPTM4B expression with highest expression in current smokers and lowest in non-smokers ( P < 0.01).