A significant trend was found across age groups for local side effects from dose 1 ( P < 0.01) where the 20- to 29-year-old and 30- to 39-year-old groups tended to report more side effects than other age groups ( Fig. 5D ).
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We then searched for KEGG-based pairs whose spatial correlations follow a trends, and found that 17% of the pairs exhibit a significant trend (257/1496, FDR corrected p -value<0.01, F-test from fitting a linear regression model, as compared with the constant model).
A significant trend toward a higher Etest MIC result was observed among these results for the two compounds (p < 0.01).
There was a significant trend for White patients to be more readily offered CAR-T than their non-White counterparts (offered CAR-T: 29% vs 6%; P <0.01), with BsAbs also more likely offered to White patients (offered BsAbs: 21% vs 8%; P =0.096).
From the pooled data we derive that the overall force/CSA is higher among the C57BL/10 mice compared to mdx (ANOVA, p < 0.01) independent of temperature, and there is a significant trend toward increasing force with increasing temperature (ANOVA, p < 0.01) for the overall data set.
Utilizing a slope model of individual regression lines for each subject to determine the consistent change in indexed stroke volume over the course of exposure, there was a significant trend of an increase in stroke volume over time ( p < 0.01) Supplementary Fig. 4 .
Based on 24 cases only, a significant trend towards an increased number of patients with thyroiditis was observed among females (3.3% in 1993-1997 to 5.0% in 2008-2013, p < 0.01) ( Table 1 ).
A significant trend toward increased number of resistant strains over time was observed only in GC_91 isolates ( r 2 = 0.607; p < 0.01; Table 4 ).
[ 63 ], conducted a case-control study in the USA and found a significant trend for increased breast cancer risk in post-menopausal women exposed to high PAH levels at birth ( P = 0.01), with ORs ranging from 1.94 to 2.42, suggesting a dose-response relationship.
Comparison of the distribution of SCAI SHOCK stages revealed a significant trend towards a higher proportion of stages D (64.7% vs. 25.0%, P < 0.01) among the 1‐year non‐survivors.
Multiple data comparisons were performed using the Tukey method, with differences considered significant when p ≤ 0.05 and highly significant when p ≤ 0.01; values of 0.05 < p < 0.1 were considered a significant trend. 3.
The sensitivity analysis results revealed a significant trend across UACR tertiles and ACM among participants aged <80 and with no CVD history, respectively ( p < 0.01 for trend). 3.3 ROC analysis of UACR predictive value for ACM in DM The ROC analysis results demonstrated the UACR prognostic value for ACM.
In terms of lung cancer, sensitivity analysis using adjusted estimates only showed a significant trend towards a higher incidence of lung cancer among HF patients [HR, 1.68 (95% CI: 1.13–2.49), P = 0.01] (see Supplementary material online , Figure S9 ).
7 a), while protein breakdown demonstrated a significant trend (p = 0.01, Fig. 7 b).
This was a significant trend at the 10% level ( X 2 = 6.523, p = 0.0106).
We next compared the frequency of TOX expressing T EM cells over time and observed a significant trend toward increasing cell frequency among patients with non-sustained MRD negativity and prior HDM-ASCT (Wilcoxon rank-sum test P = 0.011, Fig. 3b ).
Binary logistic regression analysis showed a significant trend of association between TNK treatment and lower END risk [odds ratio (OR) = 0.069, 95% confidence interval (CI): 0.009–0.545, p = 0.011].
Sensitivity Analyses (1) In patients with complete SUA data, we also found a reduced risk of AMI associated with lower SUA levels among allopurinol current users (AOR <6 mg/dL = 0.70; 95% CI: 0.53–0.91; AOR 6–7 mg/dL = 0.88; 95%CI:0.63–1.24; AOR >7 mg/dL = 1.03; 95%CI:0.76–1.40) showing a significant trend ( p = 0.011) ( Table 3 ); (2) the exclusion of hypertension from the adjusted model had no impact in the AOR estimates. 4.
Survival On survival analysis, there was a significant trend of the worst OS of advanced-stage patients based on FIGO 2009 ( P = 0.011 ) ( Figure 2A ) and FIGO 2018 staging ( P = 0.02 ) ( Figure 2B ), respectively.
The relationship between FS and FNPA was explored, and a significant trend was noted with FNPA scores in this population; however, a limited range of FS scores may have affected this finding ( β = 0.534, CI 0.126, 0.941; p = .011).
A significant trend across the BMI Z-score categories was found for the perceived difficulties in walking and jumping only in the hospital group ( p = 0.011 and p = 0.013, respectively) ( Figure 1 and Figure 2 ).
Hence, 15 patients were included in this subanalysis, showing a significant trend for longer time intervals for reaching no detectable levels of Em-18 across tertiles of SUVratio (p = 0.011); the median time to reach no detectable levels of Em-18 was 3.8 years (95% CI 2.4–n.a.).
To determine whether PEMT expression decreased with increasing severity of hepatic fibrosis, we examined RNA-sequencing-derived expression data among different fibrosis stages, and observed a significant trend in decreasing PEMT levels with cirrhosis < incomplete cirrhosis < bridging fibrosis (β = −1.185; p = 0.011).
There was a significant trend with regard to sex; females presented as significantly more anxious ( P = 0.011), whereas males presented as significantly more depressed ( P = 0.037) ( Figure 4 B).
A significant trend was observed in the subscale Enjoyment of Food and Emotional Overeating in children with obesity ( p = 0.011 and p = 0.008), abdominal obesity ( p = 0.031 and p = 0.017), and cardiometabolic risk ( p = 0.036 and p = 0.049) in the non-EBF group, compared to those who were EBF up to 6 months of age.