“a pronounced trend”

The insomnia group exhibited a markedly higher predicted brain age compared to chronological age (uncorrected mean BAG = 8.10 years; age-adjusted mean BAG = 1.60 years; both p < 0.001), indicating a pronounced trend of advanced brain aging and accelerated decline.

The effects of sub-MICs on biofilm growth did not show such a pronounced trend.

As clearly illustrated in Figure 7 , there is a pronounced trend indicating the mobilisation and transport of Mn from the anode to the cathode.

We observed a pronounced trend in which APA events involving 3′ UTR shortening significantly outnumbered those showing 3′ UTR lengthening.

( 14 ) similarly observed in their bibliometric analysis of nursing AI trends that research focus has expanded from foundational education to medical record management and intelligent decision support, revealing a pronounced trend toward cross-domain integration.

The KA profiles had a pronounced trend toward up-regulation with a few down-regulated miRNAs detected.

In SK-BR-3 cells, the CYTOR-increasing drug-dependent effect did not reach statistical significance but demonstrated a pronounced trend.

Of particular interest, DLG1 and GDNF showed a pronounced trend of over-expression in LUSC (Fig. 14 ).

Through a detailed examination of five studies, we found a pronounced trend suggesting that uncontrolled DM significantly correlates with an increased risk of ED, while the influence of BMI on ED prevalence among diabetic men appeared to be less definitive.

The differences in the antibody titers induced through the different DNA- and protein-based vaccines did not reach statistical significance, although recombinant proteins showed a pronounced trend to induce higher antibody titers than vector DNAs at the dosages used here ( Figure 3A ).

As shown in Table 1 , Among the older adults residing in long term care facilities, a pronounced trend of aging is observed, with individuals aged 70 and above accounting for 61.03% of the total.

[ 81 ] establish that the EAI of soluble proteins depends on the hydrophilic-lipophilic balance, affected by pH, with a pronounced trend in basic pH.

The findings revealed a pronounced trend: every teacher reported at least one anxiety-accommodating behavior, with 71% indicating frequent use.

Although the results showed no significant differences ( P = 0.065) in 72-h survival rates, they indicate a pronounced trend toward reduced mortality with the interventions, underscoring a critical therapeutic benefit.

4, A and C ) show a pronounced trend of narrowing and deepening of the channel.

The visualization in Figure 5 highlights a pronounced trend in which a significant number of RGDs showcase consanguineous marriages, particularly first-cousin marriages.

By 2017, and more prominently in 2020, the local Moran’s I index reached 0.071, with a pronounced trend of provinces converging in the first quadrant.

It was identified in the present work that Lachnoclostridium exhibited a pronounced trend of enrichment in HTN-F, which is consistent with the findings of Moira D and colleagues, who also reported a positive correlation between Lachnoclostridium and SBP [ 35 ].

5a ) reveal a pronounced trend: the binary alloy’s hardness escalates with extended aging.

However, the trends varied between the age groups, and in the younger age groups, there was a pronounced trend of decreasing job insecurity with urbanisation status ( Fig. 2 c).

Conclusions There has been a notable increase in average screen time among adolescents since the onset of the pandemic, with the orphanage group exhibiting a pronounced trend.

Globally, a pronounced trend towards strong opioids—particularly in non-cancer patients—is described [ 13 , 14 ].

A pronounced trend was also observed in the ITT-VP population although differences did not reach the level of statistical significance.

Particularly in TXI mode 1, there was a pronounced trend of improved visibility in macroscopic type 0-IIc or 0-IIb lesions compared to type 0-IIa or IIa+IIc lesions.

It is necessary to conclude with an acknowledgement that, while this study does cast doubt on the general hypothesis of Reisz & Frobisch (2014) that the earliest herbivores showed a pronounced trend towards larger body size, one should be careful about expanding the inferences presented here to other clades.