“a positive trend”

Additionally, scRNA-seq analysis of six LAM patients revealed that the proportion of CCL14+ endothelial cells (ECs) within the endothelial compartment exhibited a statistically significant positive correlation with the expression of inflammatory gene sets in immune cells ( r = 0.9429, p = 0.0127) and a positive trend with the expression of metastasis-associated gene signatures in LAM cells ( r = 0.7714, p = 0.1028) and T cell inhibitory signatures ( r = 0.7714, p = 0.1028) (Fig. 3 F–H).

In fact, the process of muscle degeneration according to aging is naturally intrinsic and a positive trend was found in the male group also ( p = 0.103).

For provinces in the Lombardy region where at least ten samples were available, there was a positive trend between the proportion of dogs that tested positive and the recorded burden of human disease (Spearman’s r = 0.771, p = 0.103) (Fig. 2 ) (Source data S2).

Correlation analysis suggested a positive trend (Spearman ρ = 0.771, P = 0.103; Extended Data Fig. 10c ).

Correlation of Circulating sEVs with Echocardiographic Parameters There was no significant correlation between the pre-OP levels of sEVs with aortic jet velocity ( Figure 4(a) , p = 0.1977) or shear stress ( Figure 4(b) , p = 0.4815), but a positive trend with the EOA ( Figure 4(c) , p = 0.1049).

A positive trend between high concentrations of HIF-1α and expression of p21 ( P = 0.105) was noticed, and there was a significant inverse association between Bcl-2 ( P = 0.025) and HIF-1α expression.

A positive trend was also observed for FGF19 levels ( ρ = 0.26, p = 0.106).

In contrast, while ANXA3 expression showed a positive trend, its correlation did not reach statistical significance ( r = 0.12, p = 0.106).

TNF-α had a positive trend (β = 0.723, p = 0.107), while IL-8 showed a negative trend (β = −0.791, p = 0.109).

Although this represents a positive trend, the difference was not statistically significant (χ2 = 2.60, p = 0.107).

In contrast, while the introduction of penicillin G in 1945 showed a positive trend of 3.0% annually, this change was not statistically significant ( p = 0·107, 95% CI -1·0–7·0).

In HFpEF there was a positive trend with regard to the combined event ( p = 0.107), with an ARR of 9% and an RRR of 15%.

In males, a significant positive correlation emerged between %LG and time spent on the open arms (n = 12, r = 0.690, p = 0.013; Figure 1A ), whereas in females this was only a positive trend (n = 11, r = 0.511, p = 0.108; Figure 1B ).

Although a positive trend was observed for the week variable (coefficient = 0.345, p = 0.108), it was not statistically significant, suggesting that seasonal patterns may have overshadowed the time-based effect.

For kin trials, we again found a positive trend for the intercept term (estimate = 0.248 ± 0.154 (SE), P = 0.109).

However, within patients with AUD there was a positive trend for a correlation between CHIME total and volumes of the left ( r = 0.242, p = 0.109) and right ( r = 0.254, p = 0.092) MD-TN.

The comparative analyses were also performed using only fish species with at least 3 individuals, and revealed a positive trend although not significant between total parasite abundance and spleen weight (p = 0.17) and a negative trend between parasite abundance and gonad weight (p = 0.11) in females.

Interestingly, we found only a positive trend of cytoplasmic ( p = 0.11, Kruskal–Wallis test) and membranous ( p = 0.13, Mann–Whitney U test) PSMA expression levels correlating with PSMA-PET positivity, which did not reach statistical significance.

The largest observed correlation was a positive trend between SOGS and posterior-temporal alpha coherence (T5–T6: r = 0.31, p = 0.11), but this did not reach significance.

Similarly, the PRL/FSH ratio showed a positive trend with nighttime SBP (r = 0.195, P = 0.110).

Last, we found a positive trend for the physical trainers between anterior cingulate cortex from T1 to T3 and VO 2 Max at maximal T2 ( p = 0.13) as well as a negative trend for the physical trainers between anterior cingulate cortex from T1 to T3 and RPE from T1 to T3 ( p = 0.11).

Regorafenib group showed significantly longer PFS than placebo group with no significant increase of severe toxicities, but OS improvement of regorafenib showed only a positive trend (5.8 vs. 4.5 months, HR = 0.74, P = 0.11).

Weighted linear regression between CR rate and mean Hb values, showed a positive trend, with the likelihood of response increasing at higher Hb values ( p = 0.11).

Platelet activation with CRP showed a positive trend ( p = 0.11) to further increased THP-1 cell migration.

In addition, there was a positive trend between change in SIS Strength and change in SIS ADL (ρ = 0.367, p = 0.111), although this did not reach significance.