Intensified treatment with triplet chemotherapy (FOLFOXIRI) combined with panitumumab was evaluated in phase II trial VOLFI, a numerical trend towards improved OS was noted. 63 The panel prefers waiting for more solid and long-term data before approving this treatment option, currently, it is not recommended.
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“a numerical trend”
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p=0.09
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The region has 46 forest villages in total, with significantly fewer villages in these two small areas than in the neighboring HH-type third-level watershed agglomeration area and the non-significant third-level watershed area, resulting in a numerical trend of “low-lying” villages.
On day 4 PI, there was a numerical trend for an increased acetic acid percentage in the challenged groups (P treatment = 0.057), and at day 8 PI, the PRO group showed a higher acetic acid concentration compared to other inoculated piglets ( p = 0.004).
Gemini 2.5 Flash showed a numerical trend toward slightly higher overall performance, with higher mean scores for accuracy and completeness (accuracy: 4.60 ± 0.56; completeness: 4.70 ± 0.47).
Nonetheless, those patients who had ≥12 months of PFS during prior palbociclib‐based therapy only had a numerical trend towards PFS improvement compared with those patients who had less than 12 months of PFS during prior palbociclib‐based therapy (median PFS: 7.0 vs. 5.0 months, log‐rank p = 0.931).
There was no significant difference in rate of recurrent ischemic events at 90 days for patients who were DWI positive versus negative, though there was a numerical trend toward higher recurrence rate with DWI positivity.
In evaluating the ability of a wireless motility capsule to detect pharmacologic effects on gastric contractility, we found a numerical trend towards an increased number of contractions after administration of erythromycin and a decreased frequency of gastric contractions with the administration of morphine, particularly using 20 mmHg above baseline as the contraction threshold.
3 A) and a numerical trend for increasing STEMIs toward reopening.
Intra-operative hypotensive events occurred numerically more often under SA, in a direction compatible with the known hemodynamic profile of spinal anesthesia in older adults [ 34 ], although the adjusted difference did not survive BH-FDR correction ( Table 4 ), so this remains a numerical trend. 4.2.
Pulse rate remained largely unchanged with all three drugs, although azelnidipine demonstrated a numerical trend toward greater pulse-rate reduction.
There was a reduction in all dose groups from baseline to Week 6 in the percentage of patients experiencing IDC, with a numerical trend favoring the 100 and 200 U groups (Figure 3C ).
There was a numerical trend towards earlier diagnosis over time, with stage IIIA NSCLC diagnosed in 33.2% of the 2000–2002 cohort, versus 46.5% of the 2012–2013 cohort.
(2015) evaluated riluzole as an adjunct to serotonin reuptake inhibitors (SRIs) but failed to show statistically significant superiority over placebo despite a numerical trend favoring riluzole [ 28 ].
There was also a numerical trend toward reduction in respiratory failure and mortality with use of CD24Fc (22 vs. 28%), but these results were not significant, as the study was not powered for these outcomes.
The exploratory subgroup analysis suggested a numerical trend favoring paclitaxel-ramucirumab among patients who experienced neuropathy during first-line treatment.
AS alone resulted in weight loss comparable to sham and TBI alone, whereas the combination of TBI + AS showed a numerical trend toward nearly doubled weight loss compared with single AS or TBI exposure; however, this difference did not reach statistical significance (Fig. 4 A).
While the difference did not reach statistical significance, the DSP group showed a numerical trend toward shorter procedure times.
Unlike prior studies of untreated psychosis, 32 we did not see a higher neuromelanin-MRI signal in those with FES compared to healthy controls, but noted a numerical trend in the relevant voxels (eFigure 2 in Supplement 1 ). 27 Alongside the lack of power, it is possible that the limited effect of FES on neuromelanin-MRI signal is due to treatment effect.
This may explain the nonsignificant difference in GAPP <3, despite a numerical trend.
Although not statistically significant (p = 0.051), there was a numerical trend toward higher 30-day mortality in patients who received inappropriate initial antimicrobial therapy (OR, 7.22, 95%CI 0.74-107.88) (Table 5 ).
Although no statistical differences were observed for the appeal indices, a numerical trend may be seen (Table 1 ), and perhaps a larger sample size might yield an appreciable outcome.
The YS-90 showed a numerical trend toward the highest heat detection and pregnancy rates, rather than demonstrating the highest, suggesting a possible relationship between supplementation duration and reproductive success [ 37 ].
In the IMspire150 study, triple therapy showed a significantly better PFS in patients with elevated LDH as well as a numerical trend towards better outcomes in patients with a high tumor mutational burden [ 30 ].
There was a statistically significant increase (p=0.019) in Tregs in responders versus non-responders, in addition to a numerical trend for increased overall baseline CD3 T cells and CD8 T cells in responders.
However, a numerical trend was observed for OS in favor of Isa‐Kd compared with Dara‐Rd after matching adjustment. 3.4.