“a favorable trend”

The yearly survival rates of the patients, along with the appropriateness of prescriptions and DDDs of polymyxins exhibiting a favorable trend, are depicted in Figure 1 .

Conclusions In conclusion, results from the first study to examine the impact of three weeks of non-shellfish derived glucosamine supplementation against a placebo in a randomized, crossover fashion in healthy men and women revealed significant improvements in functional outcomes such as stomach bloating in addition to a favorable trend towards improvements in ratings of constipation and hard stools.

The group that received this treatment showed a favorable trend in median survival (16.6 vs. 10.9 months); however, it was not statistically significant ( P = 0.755).

In our study, receipt of radiotherapy was independently associated with better survival, and longer chemotherapy duration showed a favorable trend in exploratory analysis.

The median RFS was 21.7 months in the CY+ group and 30.6 months in the CY− group, showing a favorable trend in the CY− group but no statistically significant difference ( p = 0.357) (Figure 2A ).

Other interventions, such as TEII (SMD = 0.48) and TWDT (SMD = 0.37), also showed trends of being showed a favorable trend to the control group, but with wider confidence intervals and greater uncertainty.

Although GLP-1RA prescription was not significantly associated with a reduced risk, it demonstrated a favorable trend (HR, 0.65; 95% CI: 0.37–1.14).

Overall, the IVTA group showed a favorable trend with fewer inflammatory recurrences and structural complications, thus suggesting a protective role of intraoperative IVTA against postoperative adverse events [ Table 6 ].

Iba et al demonstrated a favorable trend for AT supplement at a dosage of 3000 IU/day over 1500 IU/day for the treatment of sepsis-associated DIC. 13 In the treatment of Septic DIC, it may be necessary to adjust the optimal dose, taking into account not only the difference in source of infection, but also the severity of the patient’s illness and the status of coagulation-fibrinolytic disruption.

From the scant evidence that emerged about the treatment of cocaine use, it was not possible to highlight a favorable trend for dynamic or non-dynamic treatments for both outcome use and outcome participation.

LDL cholesterol presented a favorable trend (CI: −22.79 to 3.46), although not statistically significant.

While a favorable trend toward prolonged PFS was observed for the entire cohort with LR, the benefit reached statistical significance only in type II PVTT.

Although intervention within 24 h showed a favorable trend in severe cases, it did not significantly improve outcomes compared with 24–72 h. status released display-pdf yes is-in-collection-domain yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Revised 2025 Apr 23; Received 2025 Mar 9; Accepted 2025 May 9; Issue date 2025 Aug. 1.

Subgroup analysis showed benefit with CTLA-4 inhibitors (HR = 0.75; 95 % CI: 0.64-0.89; I 2 = 66 %) and a favorable trend with PD-1 inhibitors (HR = 0.72; 95 % CI: 0.51-1.03; I 2 = 87 %), though not statistically significant.

Establishing generalizable treatment algorithms for these patients remains challenging, but our data suggest a favorable trend toward the use of internal endomedullary fixation coated with PMMA.

13 ), it can be observed that from 1985 to 2020, the area of RSEI with sen > 0 accounted for 46.51% in the BTHSH region, suggesting that the eco-environment in this region demonstrated a favorable trend over the time series, and the area with sen < 0 accounted for 53.88%.

The results suggest a continuing decline in the global burden of KC among both males and females, indicating a favorable trend (Fig. 5 ).

However, the 5-year survival rate rises to 60% when surgical and radiation therapy are combined, indicating a favorable trend when surgery is added [ 136 ].

Although the difference did not reach statistical significance, a favorable trend toward improved wound closure was observed in the GPP@VP NIR group.

Biochemically, the 12-week rhythmic walking intervention led to significant reductions in TC, LDLC, TG, and the TG/HDLC ratio, with a favorable trend in the TC/HDLC ratio.

The pooled analysis for all-cause mortality showed a favorable trend (OR 0.63), however the confidence interval (0.33–1.20) crossed unity, indicating the data remains underpowered to confirm statistical significance for mortality as a stand-alone endpoint.

In this study, the music intervention was also associated with a favorable trend toward lower rates of PONV (27.6% vs. 47.9%) and insomnia (23.4% vs. 41.6%); however, these differences did not reach statistical significance.

Our analysis did not find a significant difference between RD and LF groups, although a favorable trend was observed in LF patients in terms of VAS scores for back pain.

Moreover, the improvement in RL min is accompanied by a reduction in the matching thickness, which is a favorable trend for high‐temperature EMW absorbers.

Although we failed to show a statistically significant reduction in alcohol use, we did show a favorable trend, and reduction in alcohol use was not the primary outcome of this small proof-of-concept pilot trial.