“a favorable trend”

The number of patients with CD274 amplification evaluated in the present study is the largest to date, and a favorable trend for TTNT and response rate in patients treated with ICIs was observed for the CD274 -amplified group compared with the matched CD274 -non-amplified group.

Although the addition of PPIA may show a favorable trend, it does not appear to confer a clear additive benefit beyond that achieved by MDZ alone.

5 Our findings, which indicate a favorable trend for survival outcomes, 1 support the use of pCR as a surrogate endpoint for survival outcomes in gastric cancer, particularly in the context of perioperative immunotherapy.

Upon exclusion of patients who died for reasons unrelated to TNBC at each time point, a favorable trend in breast cancer-specific survival was observed ( Table 2 ).

Conclusion: There is a favorable trend towards using conduits as prophylaxis of symptomatic neuroma formation since the nerves in which they were used showed fewer clinical signs of neuroma formation six months after surgery.

Over the following days, a favorable trend in the patient’s condition was observed with improved general medical condition and reduced pain syndrome.

Regarding PFS, a favorable trend was recorded in cases of younger patients with methylated MGMT and without residual tumor volume but without statistically significant values.

Nonetheless, a favorable trend was observed.

Although the differences between the two groups were not statistically significant, these data demonstrated the success of the surgery and a favorable trend in postoperative recovery.

Introduction Despite a favorable trend over the last two decades, neonatal sepsis is still a major cause of morbidity, mortality, and antibiotic use among neonates, with an incidence of 1–4 per 1000 live births rising up to 12–17% in very low birth weight infants (VLBWi) [ 1 ].

For positive well-being outcomes (e.g., vitality, quality of life), green exercise also showed a favorable trend, although the effect was not statistically significant (SMD = −0.48, 95% CI: −1.08 to 0.13) ( Supplementary Figure S5 ).

This group showed a favorable trend to a higher mean age, but this difference was not statistically significant (p = 0.06).

Consistent with this, a 12-week mHealth program incorporating multiple behavior-change strategies showed a favorable trend toward improved PSQI scores [ 72 ], and an earlier systematic review reported that telecounseling may improve sleep difficulties as part of broader comorbidity management, although the evidence base was small [ 54 ].

The subsequent OptiTROP-Breast02 phase III trial demonstrated efficacy in previously treated HR+/HER2− metastatic breast cancer, with sac-TMT achieving a median PFS of 8.3 months versus 4.1 months with chemotherapy (HR 0.35; 95% CI, 0.26–0.48; p < 0.0001), along with a favorable trend in overall survival. 43 Biomarkers of response and resistance Identification of biomarkers to guide ADC selection has become increasingly important considering increasing number of agents available.

The experimental arm was associated with a favorable trend toward improved EFS versus RCT and placebo, but the difference did not reach statistical significance ( 20 ).

The Luo group also exhibited a favorable trend, suggesting the intervention positively enhances gut microecological function and restores core microbial composition.

Abstract Introduction In a previous report, we demonstrated a favorable trend for supplementation with antithrombin (AT) concentrate at a dosage of 3,000 IU/day over 1,500 IU/day for the treatment of sepsis-associated disseminated intravascular coagulation (DIC) in patients with an AT activity of 70% or less.

Notably, the risk for heart failure was observed to further decrease from the 1980s into the 1990s, suggesting a favorable trend.

With a few exceptions (ACE inhibitors, antidiabetics, and statins), no pharmacological treatment showed a favorable trend (i.e., higher frequency in survivors); whereas, patients treated with aldosterone antagonists were significantly more frequent ( p < 0.001) in non-survivors (30.0% vs. 13.8%).

Follow-up at six months and beyond showed a favorable trend in visual function in 27/34 eyes.

The FP regimen demonstrated a favorable trend (HR = 0.68; 95% CI: 0.25–1.87), though not statistically significant, suggesting a need for further validation.

In the long-term (>100 months) the Kaplan–Meier-graph of TBI and ICH/aSAH patients showed a favorable trend compared to patients with CP after ischemia.

In addition, we also found a favorable trend of SBP decreasing in the intervention groups, although the mean difference change in SBP was borderline-significant.

Five RCTs recruiting 269 cases with DED provided usable data on Schirmer’s test scores, 25 , 28 , 30 , 34 , 36 and pooled results showed no significant difference between the two groups, but a favorable trend for CsA over ATs (WMD 0.45, 95% CI −2.25 to 3.15).

Our findings showed a statistically significant improvement in UCVA for the overall cohort, with the PKP subgroup achieving significance, while the LKP subgroup showed a favorable trend.