“a favorable trend”

Despite therapeutic effects observed in phase II clinical trials ( Sermet-Gaudelus et al., 2010 ; Wilschanski et al., 2011 ), ataluren treatment only demonstrated a favorable trend, albeit not significant, to improve ppFEV 1 of CF patients carrying a nonsense CFTR mutation in at least one allele in a phase III clinical trial ( Kerem et al., 2014 ).

Although adherence to the AGA guidelines for osteoporosis prevention was overall poor in our cohort, we observed a favorable trend of increasing adherence to the guidelines since 2003.

In contrast, flowering traits (female and male flowering, FF and MF), plant height (PH), and ear height (EH) exhibited negligible gains across all indexes, indicating limited selection pressure or unfavorable correlations with the main selection target (grain yield) suggesting a favorable trend toward more compact plants, which is desirable in tropical environments for lodging resistance and mechanical harvesting.

Finally, from the simulation outcomes for delays, it can be concluded that the time taken for information to traverse from a source to a destination showcases a favorable trend with time, indicating an optimized and expedited data dissemination process.

The results indicated a favorable trend of relieving leucopenia when Shenqifuzheng + NP regimen, Shenmai + NP regimen, Shengmai + NP regimen, Shenfu + NP regimen, Kangai + NP regimen and Delisheng + NP regimen were applied.

However, patients receiving LR showed a favorable trend in 2-year DFS (HR=1.40, 95% CI: 1.16–1.69) and 5-year DFS (HR=1.37; 95% CI: 1.05–1.77), although these results are not conclusive due to underpowered significance.

When evaluated as a continuous variable, number of MBD ED encounters pre- vs post-enrollment showed a favorable trend for the intervention but did not reach statistical significance (OR = −0.24, P = 0.06 for the combined study results).

SOD also showed a favorable trend (SMD = 1.02; 95% CI: −0.84 to 2.88), although with wide variability and a lack of statistical significance.

5 Furthermore, ExTRa Mapping enabled more accurate AF rotor identification, resulting in a favorable trend toward improved outcomes beyond conventional PVI.

A reduced incidence of a severe LARS with rates of 9% in the TNT and 22% in the non-TNT-group ( p = 0.23) showed a favorable trend of functional outcome in the TNT group.

7 The authors reported no differences between the treatment and control groups for cardiovascular events, cardiovascular deaths, or total mortality, but immediately added that “a favorable trend for all these end-points occurred in some younger age groups.” In contrast, Ramsden and colleagues now suggest the possibility of increased risk of death in older adults among the participants given more linoleic acid. 2 The findings of the two teams of authors do not differ fundamentally, but their interpretation does.

Moreover, a prior study showed that changing from adjuvant cisplatin and 5-fluorouracil to induction cisplatin and capecitabine caused a favorable trend of increasing efficacy with less toxicity in LA-NPC [ 8 ].

These findings indicate that main dishes and soups are the key protein sources in long-term care hospital meals, and the high inclusion of fish represents a favorable trend.

Moreover, interventions involving aerobic exercise and dietary restriction seemed to show a favorable trend concerning to WM. 4.1.

A favorable trend was seen for all pre-defined outcome variables which indicates that the lifestyle advice delivered via SMS may have contributed to the improvement.

In the ADAURA trial, patients with stage IB demonstrated a favorable trend in 5-year OS (94% vs 88%, hazard ratio [HR], 0.44; 95% CI, 0.17-1.02). 6 However, the magnitude and consistency of the benefit of adjuvant targeted therapy (ATT) in this subgroup remain ambiguous when compared with adjuvant chemotherapy (ACT) or placebo, particularly in terms of OS. 9 Emerging data

Since the results in humans for rhBMP-2 application for bone regeneration in MRONJ show a favorable trend, more studies with larger sample sizes, uniform methodology, and prolonged follow-up are required to confirm these findings.

Therefore, our results are best interpreted as showing a favorable trend rather than definitive evidence of complication reduction.

While some studies have reported an increased rate of infection in older patients, others have observed a favorable trend with increasing age.

Although exercise-based CR had no statistical effect in decreasing left ventricular end-systolic dimension (LVESD) and left ventricular end-diastolic volume (LVEDV), it showed a favorable trend in relation to both.

Although a favorable trend in hepatitis B mortality was observed between 1990 and 2019, a recent analysis indicated that this pace of decline remains insufficient, as persistent gaps in diagnosis and treatment continue to fuel the burden of advanced liver disease. 3 , 4 Consequently, China faces formidable challenges in achi

The risk of death was substantially lower among patients with dMMR/MSI-H disease (HR 0.32; 95% CI 0.17–0.63), while a favorable trend toward improved overall survival was observed in the pMMR/MSS population (HR 0.79; 95% CI 0.60–1.04) ( Powell et al., 2024 ).

In the CKDB-322 group, triglyceride levels showed a favorable trend, decreasing by −17.48 ± 61.32 mg/dL, while the placebo group experienced an increase of 12.33 ± 53.06 mg/dL.

Instead, a descriptive analysis of the data revealed distinct trends: DPE appeared to offer a favorable trend for tumor control in extremity tumors.

20.4) and a favorable trend in OS compared with those who continued systemic therapy alone, validating the role of surgery as a consolidative treatment in responders [ 107 ].