“a clear trend”

Correlation of COX-2 expression with 5-year patient survival revealed no significant correlation with overall survival, although a clear trend was observed for reduced survival in patients with high COX-2 expression ( p = 0.2).

In the pPR group (TRG 1b/2), no statistically significant survival benefit was observed, although a clear trend toward improved outcomes with adjuvant chemotherapy was noted (OS: HR 0.62, DFS: HR 0.61, P = 0.2 for both).

We observed a significant ( p < 0.05) rise upon ADP stimulation (in total PPP) of miR-223-3p, miR-151a-5p, and miR-24-3p as well as a clear trend ( p < 0.2) towards upregulation for miR-199a-3p, miR-191-5p, miR-126-3p, miR-28-3p, miR-27b-3p, and miR-21-5p.

For IL13, another important regulator of inflammation with proinflammatory functions, there was a clear trend, albeit not statistically significant (p=0.222; Figure 4 ), for increased levels of mRNA in the MBL null group.

Kaplan–Meier survival analysis of AnxA6 with outcome in PDAC Kaplan–Meier survival analysis carried out using GraphPad PRISM revealed a clear trend towards high AnxA6 expression (IHC score 3+/4+) being associated with a poorer outcome in the 57 PDAC cohort ( P =0.2242); however, this failed to reach significance.

In the high-cytogenetic-risk group, although there was a clear trend favoring group 1, the OS difference was not statistically significant—1068 days for group 1, compared to 693 days in group 2 ( p = 0.246) ( Figure 10 ).

On the non-affected hand, the MDT did not significantly change, although there was a clear trend toward lower MDTs (1.28 ± 0.26 mN, p = 0.25).

The cumulative natural abortion rate showed a clear trend of UHOR group>UPOR group>NOR group ( P = .266). 3.2.

A clear trend was detected showing higher GPC for the T allele of TDsat2.i1.1 ( Supplementary Figure 8 , Supplementary Table 2 ; P-value = 0.30).The A-allele of the KASP marker TDsat2.e9.1 was greatly underrepresented; thus, its effect cannot be assessed using this panel. 3.4 sat2 is predominantly expressed in grains Comparative transcriptomics approaches are crucial in transferring biological information, particularly conserved gene functions from better-studied species ( Zuluaga et al., 2023 ).

Successful mechanical resynchronization after CRT-P implantation was demonstrated by a clear trend towards reduction in SPWMD from 153.3 ± 94.5 ms to 53.3 ± 15.3 ms (n = 3; p = 0.32; Figure 6D ), as well as a trend towards reduction in LVEMD ( Supplementary Figure S1 ).

However, when the same comparison was performed after separating major (intracranial, gastrointestinal or any other type of bleedings requiring blood transfusion) from minor bleedings, we found a significantly lower incidence in minor bleedings in favor of the NOACs (RR = 0.69 95% CI 0.56–0.85; p = 0.0003) ( Fig 5A ), while no statistically significant difference in the incidence of major bleedings was evident, despite a clear trend in favor of the NOACs-treated arm (RR = 0.82 95% CI 0.53–1.25; p = 0.36) ( Fig 6 ).

Effects of Parental Sequential Herbivory on Nitrogen and Protein Percentage of Progeny Plants Results from cotyledon nitrogen and protein estimation showed that overall nitrogen percentage did not differ significantly across treatments; however, a clear trend was observed (Figure 3a,b ; p = 0.367, p = 0.344).

There were no significant differences between control and CMS mice in the TST despite a clear trend (65.64 ± 4.17%, 70.50 ± 3.57%, respectively; p = 0.3720) (Fig. 1 E).

The female subgroup with heightened symptom severity at baseline showed a clear trend towards better outcomes in the ICIQ-OAB score (−1.0 (SD 2.08; n = 14) vs. −0.5 (SD 1.7; n = 26; p = 0.4172).

However, there was a clear trend towards gradually rising S-MK expression levels with advanced tumor stages as indicated in Fig. 5 (p = 0.42).

Partial Pressure and Production of N 2 O Additions of both salts did not produce a clear trend in N 2 O production with increased salinity ( p = 0.44).

Additionally, the mobility parameter in male NM does not appear to follow a clear trend, with there being no significant difference between controls of NC grade 2 (68 yo) and NC grade 3 (73 yo) ( p = 0.453542).

Whilst there appears to be a clear trend in the data, as indicated by the relative height of the histogram bars, these differences were not statistically significant (ANOVA, F (7,23) = 1.01, p = 0.46).

On the other hand, RBP motifs showing positive correlation with neurite localization did not show a clear trend of being associated with higher or lower stability of the mRNA ( P = 0.47, Wilcoxon's signed rank test).

However, these differences did not show a clear trend suggesting a significant association between SPE and skeletal class ( p = 0.479).

As for overall survival, a clear trend for longer OS was observed in patients with age < 65 years (HR = 0.93, 95% CI = 0.69-1.26, P = 0.64), ECOG score = 0 (HR = 0.89, 95% CI = 0.69-1.14, P = 0.36), or never smoked (HR = 0.72, 95% CI = 0.45-1.17, P = 0.18).

While not statistically significant, BLG-sensitized DR3 males showed a clear trend for hypothermia (sham DR3: 36.5 ± 0.2°C; BLG DR3: 34.5 ± 1.0°C; p = 0.7) ( Figure 2C ).

In contrast, DRB1*0802 (Table S2) as another common allele in the DRB1*08 group did not show a clear trend for positive or negative association ( n = 16, β = 0.18 ± 0.48, P > 0.70), neither did the less frequent allele DRB1*0801 ( n = 9, β = 0.74 ± 0.64, P = 0.249).

Overweight did not show a clear trend in urban women (p = 0.796), but percentages of normal women declined, especially since 2005 (p<0.001).

Major GI surgical procedures increased over the study period ( p < 0.01), whereas appendectomy and cholecystectomy did not demonstrate a clear trend ( p = 0.90).