“a clear trend”

The control group had no significant change or a clear trend in the caspase‐9 (at 1 h −6.12%, at 6 h −2.58%, at 24 h −5.86%, p ‐value > 0.99) or caspase‐3 gene expression (at 1 h after first treatment +6.47%, at 6 h −1.21%, and at 24 h −3.15%, p ‐value 0.96), and bcl2l1 increased in the control group ( p ‐value > 0.99, at 1 h +18.97%, at 6 h +25.72%, at 24 h +10.84%).

Because the results do not show a clear trend, the uncertainty at 95% confidence interval is estimated as (12) U C p = 1 . 5 ( max C p C p , base - min C p C p , base ) = 1 . 4 % .

However, we could observe a clear trend that patients who received chemoradiation had more favorable prognosis compared with those treated with radiation alone.

Consistent with this theory, when these mice were treated beginning at seven weeks old, we did not detect such a clear trend of improvement in motor deficits (data not shown).

The Trk inhibitor landscape was however rapidly moving from exploratory tool inhibitor (such as GW441756 ) to more relevant drug leads and there was a clear trend in preclinical work and patent literature towards what has now become one of the most explored chemotypes, specifically imidazo[1,2- b ]pyridazine and pyrazolo[1,5-a]pyrimidine-based inhibitors ( Figure 4 ).

However, a clear trend to higher thicknesses was found in the ASD group, at all macular subfields and at inferior peripapillary sectors, with such differences as over 10 microns at the macular central subfield ( Figure 6 ), over 13 and 10 microns at clock-hour 6 and 5 sectors, respectively ( Figure 7 ), and over eight microns at inferior peripapillary quadrant ( Figure 8 ).

There was a clear trend of increasing RT over time ( P for trend <0.01).

A clear trend was noticeable in the decrease of resistance and reactance values with the age of the studied children, which had a significant impact on the results of obtained body composition components.

A clear trend to a lower incidence of VAP episodes was observed in patients randomized to AG group.

A clear trend of the code blob reuse dropping and then saturating after some time is visible, which is significant because it indicates that the code created in the hackathon events continue to bear some value even after 2 years have passed after the event.

A clear trend toward decreased survival of the a‐capsular kpsM mutant compared with the wild‐type was noted, with a 2‐log difference (Figure 3b ).

While the possibility of cation interaction cannot be excluded, these data demonstrate a clear trend with increasing layer separation.

Effect of flow rate on concentration profile and sensor response time The multiphysics simulations reveal a clear trend in the transport of niclosamide (NA) to the nanocomposite electrode surface under varying volumetric flow rates ( Q ) in a microfluidic channel.

77.6%, P = 0.02124), it demonstrated a clear trend favouring immunotherapy.

While the AMS Autonomous subscale showed significant differences across physical activity levels and categories of sleep quality in the Kruskal–Wallis tests, these results did not follow a clear trend, and no significant correlations emerged when sleep duration or MET–minutes/week were considered as continuous variables.

Although in this simulation a fully equilibrated final state is not achieved within the very long simulation time span, due to the slowness of folding kinetics, we find clear evidence of a partially folded state, with only about 20% of fully unfolded duplexes remaining and with nematic order parameter S ≈0.5, which shows a clear trend towards greater values as the system evolves toward full equilibration.

These results demonstrate a clear trend where increased AuNP concentration leads to higher resistance, negatively affecting charge transport.

Furthermore, a clear trend was observed, namely, that more features are susceptible to inter-scanner/observer variability than intra-scanner/observer variability.

Figure 3 I shows that the response surface did not exhibit a clear trend of increasing values as the amount of soybean lecithin increased.

Introduction With recent development of mobile intelligence, it has seen a clear trend that robots will come into interact with humans in industries, health care, medical applications, etc.

The DNA content showed a clear trend toward reduction as a result of storage in PBS‐Alg‐MC but not in Plasma‐Alg‐MC.

Previous research generally show a negative relationship between property price and distance from city center, but this dataset does not show a clear trend, thus any such relationship should be evaluated cautiously without a fitted regression line or statistical summary.

The Dia-ProSeal samples indicated a clear trend in cell viability with time ( Fig. 4c ).

There was a clear trend toward increasing acetyl tubulin over the course of the experiment, with a statistically significant ~1.6-fold increase observed on day 5.

Therefore, the main differences between plots with an average level of management and those with a high level of management are higher overall plant richness and a clear trend towards greater biodiversity among native, melliferous, weed, and species responsible for regulating and maintaining ecosystems.